Results 171 to 180 of about 111,661 (295)

The Interplay Between Ca²⁺ Homeostasis, Endoplasmic Reticulum Stress, and the Unfolded Protein Response in Human Diseases. [PDF]

Cells
Ranzato E, Martinotti S.
europepmc   +1 more source

Unfolding Plant Defence: Endoplasmic Reticulum Stress Signalling at the Plant‐Pathogen Interface

Plant Biotechnology Journal, EarlyView.
ABSTRACT The endoplasmic reticulum (ER) stress response, a conserved proteostasis network, has emerged as a central hub that reprograms plant immunity during pathogen attack. This review synthesises how plants harness ER‐stress signalling to mount multilayered defences and how pathogens have evolved counterstrategies to subvert these pathways.
Zhe Meng, Shuqin Zheng, Federica Brandizzi, Yiran Liu, Chunlei Li, Congcong Ai, Yujiao Wang, Jiadong Qi, Xiuguo Zhang   +8 more
wiley   +1 more source

Allergic Inflammation Triggers the Unfolded Protein Response and <i>Ormdl3</i> Expression in Rat Adipocytes, While miR-665 Inhibition Selectively Modulates the IRE1/XBP1 Pathway and IL-6 Secretion. [PDF]

Int J Mol Sci
Nowakowska-Lewicka J, Langwiński W, Wojciechowicz T, Skrzypski M, Narożna B, Kachel M, Sakrajda K, Stachowiak Z, Szczepankiewicz A.   +8 more
europepmc   +1 more source

One day of environment‐induced heat stress causes injury to the murine kidney

Experimental Physiology, EarlyView.
Abstract Environment‐induced heat stress (EIHS) results from sustained body temperature elevation owing to prolonged exposure to heat and humidity. We hypothesized that EIHS would cause kidney injury and cellular dysfunction. To test this hypothesis, female C57 mice were exposed to EIHS (n = 14; 37.6°C, 42.0% relative humidity) or thermoneutral (TN ...
Melissa Roths, Alyona Michael, Zachary J. Schlader, Joshua T. Selsby   +3 more
wiley   +1 more source

Metabolite import by SLC33A1 is required for ATF6 activation during endoplasmic reticulum stress. [PDF]

Life Sci Alliance
George G, Harding HP, Kay R, Ron D, Ordoñez A.   +4 more
europepmc   +1 more source

Climate change and agriculture: A selection of Cirad's expertise [PDF]

, 2015
CIRAD-PERSYST-UPR AIDA - FRA
core  

Canonical and non‐canonical functions of proteins regulating mitochondrial dynamics in mammalian physiology

The Journal of Physiology, EarlyView.
Abstract figure legend Mitochondria are highly dynamic organelles that continuously remodel their architecture through coordinated cycles of fusion and fission. This review examines the four key GTPases that orchestrate mitochondrial dynamics in mammals: MFN1, MFN2, OPA1, and DRP1.
Rémi Chaney, Vincent Marcangeli, Krystel Desjardins, Shima Taherkhani, Gilles Gouspillou   +4 more
wiley   +1 more source

Chemical modulation of the unfolded protein response reveals an antiviral role for the PERK pathway in human coronavirus 229E infection. [PDF]

RSC Chem Biol
Pellizzari-Delano IE, Tooley TH, Mondal D, Jani K, Gallardo-Flores CE, Colpitts CC.   +5 more
europepmc   +1 more source

Navigating Unconditional Positive Regard: Counsellors' Perspectives on Client Disclosures of Child Sexual Abuse Offending

Counselling and Psychotherapy Research, Volume 26, Issue 2, June 2026.
ABSTRACT Objective This study explores counsellors' perceptions of working with clients who disclose thoughts regarding, or experience of perpetrating, sexual abuse of a child. Counselling of such clients is often framed as emotionally draining, distressing and a challenge for the core conditions of a productive therapeutic relationship, specifically ...
Abigail Pustkowski, Sarah J. Manso, Amy E. Burton   +2 more
wiley   +1 more source

Early life stress-induced depression reveals distinct region-specific modulation of unfolded protein response genes in the prefrontal cortex and hippocampus of rats. [PDF]

Front Psychiatry
Griffin AK, Roy B, Dwivedi Y.
europepmc   +1 more source