Results 171 to 180 of about 75,497 (305)

The UPR in cell death and inflammation

, 2023
Cancer cells can adapt under cellular stresses, activating several signaling mechanisms for diverse outcomes. In this PhD thesis, I explored these mechanisms by which cancer cells regulate their pro-survival and pro-death responses in multiple conditions.
openaire   +2 more sources

Contrasting mechanisms driving the northward expansion of African raptors in Europe

Journal of Zoology, EarlyView.
Recent climate warming and landscape changes are enabling African raptors to reach Europe through contrasting mechanisms. Using species distribution models, we show that the Atlas Long‐legged Buzzard expands northward following climatic suitability, whereas African vultures reach Europe despite low climatic favourability through socially mediated ...
A.‐R. Muñoz, S. López‐Ramírez, J. M. García‐Carrasco, R. Real   +3 more
wiley   +1 more source

Perk Is Dispensable for Smooth Muscle Cell Phenotype Switching in Atherosclerosis. [PDF]

Arterioscler Thromb Vasc Biol
Zhu LY, Xue C, Bashore AC, Cui J, Yao S, Sachs N, Wettich J, Coronel J, Garcia EJ, Khalid S, Saleheen D, Li M, Maegdefessel L, Reilly MP.   +13 more
europepmc   +1 more source

Hypoxia induces beta cell death by inhibiting the adaptive UPR.

, 2015
Background and aims: Hypoxia is implicated in the loss of functional beta cell mass in type 2 diabetes and with islet transplantation, although the mechanisms are unknown. The adaptive unfolded protein response (UPR) is required for endoplasmic reticulum
Bensellam, Mohammed, Jonas, Jean-Christophe, Chan, J., Laybutt, D. Ross, Maxwell, E., 51st Annual Meeting of the European Association for the Study of Diabetes   +5 more
core  

Modeling the UPR in neurodegenaration

Frontiers in Neuroinformatics, 2016
Theocharopoulou Georgia, Bobori Catherine   +1 more
openaire   +1 more source

Redefining Endometrial Decidualization: The Central Role of the ER Stress-Immune-Metabolic Axis. [PDF]

Int J Mol Sci
Karaoğlan Ö, Tap Ö, Ürünsak İF.
europepmc   +1 more source

Conserved symbiosis‐associated genes in the cycad Encephalartos natalensis suggest co‐option for cyanobacterial symbiosis

New Phytologist, EarlyView.
The heterocyst‐rich Encephalartos natalensis cyanobacterial zone in coralloid root suggests co‐option of conserved symbiosis‐associated genes. This figure was created in BioRender (BioRender.com/https://BioRender.com/n3qveqc). Summary Plant‐cyanobacterial symbioses have evolved independently at least four times across land plants, yet their underlying ...
Cassandra Schoeman, Danielle Roodt, Amy Mc Menamin, Oliver Bezuidt, Choaro Dithugoe, Desré Pinard, Eshchar Mizrachi   +6 more
wiley   +1 more source

Exercise Exerts Antidepressant Effects via Endoplasmic Reticulum Stress Modulation: Molecular Mechanisms and Research Progress. [PDF]

Biology (Basel)
Zhou XY, Liu YW, Zhong CH, Xu R, Guan K, Li HN, Huang JT, Xue K, Wang Y, Chen XH.   +9 more
europepmc   +1 more source

Innovations in Obesity Treatment: Beyond Adipose Tissue Dysfunction

Obesity Reviews, EarlyView.
Obesity drives chronic inflammation, insulin resistance, type 2 diabetes, and cancer development through adipocyte dysfunction. Addressing this multisystemic disorder requires integrated strategies beyond diet and exercise, such as thermogenesis activation via menthol or capsinoids and appetite control through GLP‐1/GIP agonists and neuromodulation to ...
Jesica Martínez‐Godfrey, Irene Pomares‐Bri, Paula de Juan‐Maciá, Mariló Olivares‐Vicente, Enrique Barrajón‐Catalán, Vicente Micol, Enrique Roche, María Herranz‐López   +7 more
wiley   +1 more source

Unfolded protein response in bronchopulmonary dysplasia: mechanisms, pathways, and therapeutic implications. [PDF]

Front Cell Dev Biol
Yu H, Guo Y, Wang X, Guo W, Zhang Y.
europepmc   +1 more source