Results 161 to 170 of about 165,169 (375)

Decoding RNA–Protein Interactions: Methodological Advances and Emerging Challenges

Advanced Genetics, EarlyView.
This review provides a comprehensive comparison of RNA‐ and protein‐centric methodologies for investigating RNA–protein interactions, emphasizing their respective advantages, limitations, and suitable applications. It highlights recent technological innovations, outlines strategic method selection criteria, and addresses key challenges.
Wenkai Yi, Jian Yan
wiley   +1 more source

THE UPTAKE OF GUANINE, URACIL, LYSINE AND GLYCINE BY ASCITES CELLS PRETREATED WITH AZASERINE AND 6-THIOGUANINE [PDF]

, 1963
David H. Adams
openalex   +1 more source

Sizing and concentration analysis of cfDNA using Biabooster technology: Results from a prospective plasma‐based collection of 77 patients with locally advanced unresectable esophageal cancer

International Journal of Cancer, EarlyView.
What's New? This study introduces a novel approach for detecting locally advanced esophageal carcinoma using cell‐free DNA (cfDNA) analysis through a highly sensitive fragmentome assay. Unlike traditional sequencing‐based methods that are limited by the absence of specific mutations in esophageal tumors, our method offers an alternative by quantifying ...
Anouchka Modesto, Sophie Gibert, Caroline Delmas, David Tougeron, Amaury Paumier, Alexandre Taillez, Samuel Le Sourd, Delphine Argo Leignel, Philippe Ronchin, Ariane Darut Jouve, Véronique Vendrely, Olivier Riou, Jérôme Martin‐Babau, Thomas Leroy, Laurent Quéro, Naïma Hanoun, Pierre Cordelier, Veronica Pezzella, Jean Pierre Delord, Rosine Guimbaud, Elizabeth Moyal, Catherine Seva   +21 more
wiley   +1 more source

Mitochondrial dysfunction: Related diseases, influencing factors, and detection

Interdisciplinary Medicine, EarlyView.
Mitochondrial dysfunction is implicated in the pathogenesis of numerous diseases, including neurological disorders, cancers, and cardiovascular conditions, through mechanisms such as mitochondrial DNA mutations, dysregulation of mitochondrial network dynamics, and impaired mitophagy.
Zhaojin Li, Shiyu Li, Wanying Chen, Ziyu Zhang, Chun Pan, Peng Lei, Cheng Cheng, Junyou Zhu, Hanxiao Sun, Zhenning Dai   +9 more
wiley   +1 more source

15 Decreased Incorporation of Uracil-2-C14 in the RNA Fraction of Mouse Fibroblast Cultures Grown with Pancreatic Diabetic Insulins [PDF]

, 1967
Claude Roy, Ronald W. Gotlin, Dennis Shapcott, Donough OʼBrien   +3 more
openalex   +1 more source

Noncanonical Nucleotides in the Genome Around the Maternal‐Zygotic Transition

Journal of Experimental Zoology Part B: Molecular and Developmental Evolution, EarlyView.
In this paper, Kazzazi et al. provide a comprehensive review of the dynamics of nonconventional nucleotides in the genome during early developmental stages, hypothesizing a potential role for these nucleotides in the activation of the zygotic genome. ABSTRACT From the very moment of fertilization and throughout development, the cells of animal embryos ...
Latifa Kazzazy, Dávid Mező, Kinga K. Nagy, Viktória Perey‐Simon, Judit Tóth, Angéla Békési, Beáta Vértessy, Máté Varga   +7 more
wiley   +1 more source

Uptake and Incorporation of Thymine, Thymidine, Uracil, Uridine, and 5-Fluorouracil into the Nucleic Acids of Bacillus subtilis [PDF]

, 1965
Walter F. Bodmer, Susan Grether
openalex   +1 more source

Role of Adjuvant Chemotherapy in Distal Cholangiocarcinoma

Journal of Hepato-Biliary-Pancreatic Sciences, EarlyView.
ABSTRACT Background Recent studies addressing the role of adjuvant chemotherapy (AC) in cholangiocarcinoma (CCA) have been published; however, there are challenges in generalizing the findings due to different prognostic characteristics depending on tumor location and resectability.
Yoon Soo Chae, Youngmin Han, Go‐Won Choi, Younsoo Seo, Inhyuck Lee, Won‐Gun Yun, Hye‐Sol Jung, Wooil Kwon, Joon Seong Park, Jin‐Young Jang   +9 more
wiley   +1 more source

Synthesis and Biological Activities of Some Metal Complexes of 2-Thiouracil and Its Derivatives: A Review

Compounds
The thionamide antithyroid agents were discovered largely through observations carried out by various researchers in the 1940s that found that sulfhydryl-containing substances were goitrogenic in animals. Prof. Edwin B.
Petja Emilova Marinova, Kristina Dimova Tamahkyarova   +1 more
doaj   +1 more source

THE CATABOLISM OF URACIL IN VIVO AND IN VITRO

, 1954
Robert J. Rutman, A. Cantarow, K. E. Paschkis   +2 more
openalex   +1 more source