Results 21 to 30 of about 165,169 (375)

Uracil-Induced Down-Regulation of the Yeast Uracil Permease [PDF]

Journal of Bacteriology, 1999
ABSTRACT In Saccharomyces cerevisiae the FUR4 -encoded uracil permease catalyzes the first step of the pyrimidine salvage pathway. The availability of uracil has a negative regulatory effect upon its own transport.
Karin Séron, Christiane Volland, Rosine Haguenauer-Tsapis, Marie-Odile Blondel   +3 more
openaire   +3 more sources

Photo-Induced Coupled Nuclear and Electron Dynamics in the Nucleobase Uracil

Frontiers in Physics, 2021
Photo-initiated processes in molecules often involve complex situations where the induced dynamics is characterized by the interplay of nuclear and electronic degrees of freedom.
Lena Bäuml, Thomas Schnappinger, Matthias F. Kling, Matthias F. Kling, Regina de Vivie-Riedle   +4 more
doaj   +1 more source

5,5-Dichloro-6-hydroxydihydropyrimidine-2,4(1H,3H)-dione: molecular and crystal structure, Hirshfeld surface analysis and the new route for synthesis with Mg(ReO4)2 as a new catalyst

Acta Crystallographica Section E: Crystallographic Communications, 2020
The molecular and crystal structures of the title compound, C4H4Cl2N2O3, were investigated by single-crystal X-ray diffraction and a Hirshfeld surface analysis.
Anton P. Novikov, Sergey N. Ryagin, Mikhail S. Grigoriev, Alexey V. Safonov, Konstantin E. German   +4 more
doaj   +1 more source

Uracil-containing DNA in Drosophila: stability, stage-specific accumulation, and developmental involvement. [PDF]

PLoS Genetics, 2012
Base-excision repair and control of nucleotide pools safe-guard against permanent uracil accumulation in DNA relying on two key enzymes: uracil-DNA glycosylase and dUTPase.
Villő Muha, András Horváth, Angéla Békési, Mária Pukáncsik, Barbara Hodoscsek, Gábor Merényi, Gergely Róna, Júlia Batki, István Kiss, Ferenc Jankovics, Péter Vilmos, Miklós Erdélyi, Beáta G Vértessy   +12 more
doaj   +1 more source

Theoretical Study of Light-Induced Crosslinking Reaction Between Pyrimidine DNA Bases and Aromatic Amino Acids

Frontiers in Bioengineering and Biotechnology, 2022
Low-lying electronic excited states and their relaxation pathways as well as energetics of the crosslinking reaction between uracil as a model system for pyrimidine-type building blocks of DNA and RNA and benzene as a model system for aromatic groups of ...
Attila Bende, Alex-Adrian Farcaş, Alex-Adrian Farcaş, Valer Toşa   +3 more
doaj   +1 more source

Mechanisms of base selection by human single-stranded selective monofunctional uracil-DNA glycosylase [PDF]

, 2009
hSMUG1 (human single-stranded selective monofunctional uracil-DNA glyscosylase) is one of three glycosylases encoded within a small region of human chromosome 12. Those three glycosylases, UNG (uracil-DNA glycosylase), TDG (thymine-DNA glyscosylase), and
Agus Darwanto, Akbari, Alcantara, Barrett, Bennett, Bethod, Boorstein, Bryantsev, Cerny, Clough, Cui, Cybulski, Daniel K. Rogstad, Di Noia, Di Noia, Dunning, Fujimoto, Gait, Guerniou, Hansch, Haushalter, Hobza, Jacob A. Theruvathu, James L. Sowers, Jang, Kavli, Kelly, Kendall, Krokan, Krokan, La Francois, Lawrence C. Sowers, Liu, Marten, Masaoka, Matsubara, Matsubara, Matsudaira, Mendes, Morgan, Neddermann, Nilsen, Nilsen, Pearl, Perezjorda, Privat, Rao, Rogstad, SantaLucia, Sibghat-Ullah, Slupphaug, Sousa, Sowers, Sowers, Sugiyama, Tannor, Tod Pascal, Waters, Wibley, William Goddard, Zhao, Zhao, Zhao, Zielenkiewicz   +63 more
core   +3 more sources

Study of the structures and energetics of LiI-water-uracil anionic complexes

Xi'an Gongcheng Daxue xuebao, 2022
Anion effect and anion-cation correlation mechanism are generally not considered in the interaction between metal ions and bases. Thus the geometric structure and electronic structure of the LiI-water-uracil anionic complexes were studied by density ...
LI Renzhong, XU Xiaoyang, HUANG Jian
doaj   +1 more source

Synthesis and Evaluation of Some Uracil Nucleosides as Promising Anti-Herpes Simplex Virus 1 Agents

Molecules, 2021
Since herpes simplex virus type 1 (HSV-1) infection is so widespread, several antiviral drugs have been developed to treat it, among which are uracil nucleosides.
Samir Mohamed Awad, Shima Mahmoud Ali, Yara Essam Mansour, Samar Said Fatahala   +3 more
doaj   +1 more source

Excited States of Proton-bound DNA/RNA Base Homo-dimers: Pyrimidines [PDF]

, 2014
We are presenting the electronic photo fragment spectra of the protonated pyrimidine DNA bases homo-dimers. Only the thymine dimer exhibits a well structured vibrational progression, while protonated monomer shows broad vibrational bands. This shows that
Adesokan A. a, Ahlrichs R., Alata I., Alata I., Alata I., Alata I., Andersen L. H., Bakker J. M., Berdakin M., Berdakin M., Bouchoux G., Boyarkin O. V., Brøndsted Nielsen S., Chakraborty S., Christophe Jouvet, Claude Dedonder-Lardeux, Delchev V. B., Dopfer O., Duncan M. A., Fonseca Guerra C., Fridgen T. D., Féraud G., Féraud G., Gehring K., Grégoire G., Gustavo A. Pino, Géraldine Féraud, Góra R. W., Hattig C., Kamrath M. Z., Kamrath M. Z., Kang H., Kang H., Kang H., Kleinermanns K., Le Barbu-Debus K., Lepere V., Lieblein A. L., Marian C., Matias Berdakin, Mercier S. R., Patzer A., Pino G. A., Rajabi K., Saigusa H., Salpin J.-Y., Schermann J.-P., Schirmer J., Scuderi D., Scuderi D., Sobolewski A. L., Solcà N., Wang X. B., Yang B., Yang B., Škríba A.   +55 more
core   +4 more sources

Inhibition of acetylcholinesterase and butyrylcholinesterase with uracil derivatives: kinetic and computational studies

Journal of Enzyme Inhibition and Medicinal Chemistry, 2019
Acetylcholinesterase (AChE) and Butyrylcholinesterase (BuChE) inhibitors are interesting compounds for different therapeutic applications, among which Alzheimer’s disease.
Hüseyin Çavdar, Murat Senturk, Murat Guney, S. Durdağı, Gülru Kayık, C. Supuran, D. Ekinci   +6 more
semanticscholar   +1 more source