Results 21 to 30 of about 149,629 (313)

Study of the structures and energetics of LiI-water-uracil anionic complexes

open access: yesXi'an Gongcheng Daxue xuebao, 2022
Anion effect and anion-cation correlation mechanism are generally not considered in the interaction between metal ions and bases. Thus the geometric structure and electronic structure of the LiI-water-uracil anionic complexes were studied by density ...
LI Renzhong, XU Xiaoyang, HUANG Jian
doaj   +1 more source

Photo-Induced Coupled Nuclear and Electron Dynamics in the Nucleobase Uracil

open access: yesFrontiers in Physics, 2021
Photo-initiated processes in molecules often involve complex situations where the induced dynamics is characterized by the interplay of nuclear and electronic degrees of freedom.
Lena Bäuml   +4 more
doaj   +1 more source

Theoretical Study of Light-Induced Crosslinking Reaction Between Pyrimidine DNA Bases and Aromatic Amino Acids

open access: yesFrontiers in Bioengineering and Biotechnology, 2022
Low-lying electronic excited states and their relaxation pathways as well as energetics of the crosslinking reaction between uracil as a model system for pyrimidine-type building blocks of DNA and RNA and benzene as a model system for aromatic groups of ...
Attila Bende   +3 more
doaj   +1 more source

Synthesis and Evaluation of Some Uracil Nucleosides as Promising Anti-Herpes Simplex Virus 1 Agents

open access: yesMolecules, 2021
Since herpes simplex virus type 1 (HSV-1) infection is so widespread, several antiviral drugs have been developed to treat it, among which are uracil nucleosides.
Samir Mohamed Awad   +3 more
doaj   +1 more source

Uracil mustard revisited [PDF]

open access: yesCancer, 1999
A patient with diffuse large cell lymphoma who had a complete response lasting 35 years following a 3-day course of uracil mustard stimulated a recall review of patients treated with this oral alkylating agent.Records of patients treated with uracil mustard between 1958 and 1970 were reviewed.
B J, Kennedy   +2 more
openaire   +2 more sources

Synthesis of new alkyl derivatives of N(1)-(2’-bromo-1’,1’-difluoro-2’-chloroethyl)uracil with potential antitumor activity

open access: yesAktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2020
The most common ways of their chemical modification are used namely, electrophilic and nucleophilic substitution reactions during the purposeful search for active substances among pyrimidines with aromatic properties.
O. V. Velchynska
doaj   +1 more source

Viruses with U-DNA: New Avenues for Biotechnology

open access: yesViruses, 2021
Deoxyuridine in DNA has recently been in the focus of research due to its intriguing roles in several physiological and pathophysiological situations. Although not an orthodox DNA base, uracil may appear in DNA via either cytosine deamination or thymine ...
Kinga K. Nagy   +2 more
doaj   +1 more source

Mechanisms of base selection by human single-stranded selective monofunctional uracil-DNA glycosylase [PDF]

open access: yes, 2009
hSMUG1 (human single-stranded selective monofunctional uracil-DNA glyscosylase) is one of three glycosylases encoded within a small region of human chromosome 12. Those three glycosylases, UNG (uracil-DNA glycosylase), TDG (thymine-DNA glyscosylase), and
Agus Darwanto   +63 more
core   +3 more sources

Pyrimidine salvage in Toxoplasma gondii as a target for new treatment

open access: yesFrontiers in Cellular and Infection Microbiology, 2023
Toxoplasmosis is a common protozoan infection that can have severe outcomes in the immunocompromised and during pregnancy, but treatment options are limited.
Hamza A. A. Elati   +6 more
doaj   +1 more source

Synthesis of Some N1-Benzyl -6-(thio and alkyl or aryl thio) Uracil derivatives [PDF]

open access: yesKirkuk Journal of Science, 2013
New series of N1-Benzyl -6-(thio derivatives) Uracils have been prepared by reaction of 6-chloro uracil [F3] with benzyl chloride in dimethyl sulphoxide in presence of sodium carbonate to yield N1-Benzyl-6-chloro uracil [F4].Heating of [F4] in ethanol ...
Mohsin Omer Mohammad
doaj   +1 more source

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