Results 51 to 60 of about 137,731 (206)
Urine metabolomic analysis to detect metabolites associated with the development of contrast induced nephropathy. [PDF]
, 2016 ObjectiveContrast induced nephropathy (CIN) is a result of injury to the proximal tubules. The incidence of CIN is around 11% for imaging done in the acute care setting.
Diercks, Deborah B +3 more
core +1 more source
What the difference between Thymine and Uracil? [PDF]
arXiv, 2009 The wobble hypothesis does not discriminate between uracil and thymine. Methylation could favor further stabilization of uracil in the keto form. Thymine is present in keto form only and can pair up but with adenine. Uracil can easily construct the enol form; that is why it forms the U-G pair.
arxiv
Novel inhibition of archaeal family-D DNA polymerase by uracil. [PDF]
, 2013 International audienceArchaeal family-D DNA polymerase is inhibited by the presence of uracil in DNA template strands. When the enzyme encounters uracil, following three parameters change: DNA binding increases roughly 2-fold, the rate of polymerization ...
Connolly, Bernard A +4 more
core +2 more sources
Enol form of uracil in the GU "wobble" pair. NMR evidence [PDF]
arXiv, 2012 GU "wobble" pair may contain either the enol form of uracil and the keto form of guanine or the enol form of guanine and the keto form of uracil. A direct proof of uracil existence in enol form can be obtained by using NMR spectroscopy. In HNN-COSY experiments the GU pair imitates the GC pair due to the enolization of uracil.
arxiv
, 2016 Fine-tuned regulation of the cellular nucleotide pools is indispensable for faithful replication of Deoxyribonucleic Acid (DNA). The genetic information is also safeguarded by DNA damage recognition and repair processes.
Altschul +48 more
core +2 more sources
arXiv, 2015 Fine-tuned regulation of the cellular nucleotide pools is indispensable for faithful replication of DNA. The genetic information is also safeguarded by DNA damage recognition and repair processes. Uracil is one of the most frequently occurring erroneous base in DNA; it can arise from cytosine deamination or thymine-replacing incorporation.
arxiv
Plasmid-based lacZalpha assay for DNA polymerase fidelity: application to archaeal family-B DNA polymerase [PDF]
, 2009 The preparation of a gapped pUC18 derivative, containing the lacZalpha reporter gene in the single-stranded region, is described. Gapping is achieved by flanking the lacZalpha gene with sites for two related nicking endonucleases, enabling the excision ...
Bebenek +28 more
core +2 more sources
Thermochemistry of uracil and thymine revisited
The Journal of Chemical Thermodynamics, 2015 Peer ...
Vladimir N. Emel’yanenko +3 more
openaire +5 more sources
Secondary structure prediction of protein constructs using random incremental truncation and vacuum-ultraviolet CD spectroscopy [PDF]
arXiv, 2014 A novel uracil-DNA degrading protein factor (termed UDE) was identified in Drosophila melanogaster with no significant structural and functional homology to other uracil-DNA binding or processing factors. Determination of the 3D structure of UDE will be a true breakthrough in description of the molecular mechanism of action of UDE catalysis, as well as
arxiv
Reasons underlying certain tendencies in the data on the frequency of codon usage [PDF]
arXiv, 2009 The tendencies described in this work were revealed in the course of examination of adenine and uracil distribution in the mRNA encoding sequence. The study also discusses the usage of codons occupied by the amino acid arginine in the table of the universal genetic code.
arxiv