Comment on “Ring-breaking electron attachment to uracil: Following bond dissociations via evolving resonances” [J. Chem. Phys. 128, 174302 (2008)] [PDF]
We point out that the assignment of pi* resonances to calculated features in a recent paper by Gianturco et al. [J. Chem.
McKoy, Vincent, Winstead, Carl
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Synthesis of Uracil-Iodonium(III) Salts for Practical Utilization as Nucleobase Synthetic Modules
Iodonium(III) salts bearing uracil moieties have recently appeared in the literature, but their structural scope and utilization are limited because of their hygroscopic characteristics.
Naoko Takenaga +6 more
doaj +1 more source
Uracil arises in cellular DNA by cytosine (C) deamination and erroneous replicative incorporation of deoxyuridine monophosphate opposite adenine. The former generates C → thymine transition mutations if uracil is not removed by uracil-DNA glycosylase ...
Marina Alexeeva +13 more
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Synthesis of 1,4-Disubstituted Mono and Bis-triazolocarbo-acyclonucleoside Analogues of 9-(4-Hydroxybutyl)guanine by Cu(I)-Catalyzed Click Azide-Alkyne Cycloaddition [PDF]
A series of novel mono-1,2,3-triazole and bis-1,2,3-triazole acyclonucleoside analogues of 9-(4-hydroxybutyl)guanine was prepared via copper(I)-catalyzed 1,3-dipolar cycloaddition of N-9 propargylpurine, N-1-propargylpyrimidines/as-triazine with the ...
Engels, Joachim W. +2 more
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Thymine-Modified Nanocarrier for Doxorubicin Delivery in Glioblastoma Cells
Brain tumor glioblastoma is one of the worst types of cancer. The blood–brain barrier prevents drugs from reaching brain cells and shields glioblastoma from treatment.
Albina Y. Ziganshina +10 more
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Non-Empirically Tuned Range-Separated DFT Accurately Predicts Both Fundamental and Excitation Gaps in DNA and RNA Nucleobases [PDF]
Using a non-empirically tuned range-separated DFT approach, we study both the quasiparticle properties (HOMO-LUMO fundamental gaps) and excitation energies of DNA and RNA nucleobases (adenine, thymine, cytosine, guanine, and uracil).
Foster, Michael E., Wong, Bryan M.
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Integration of DNA into bacterial chromosomes from plasmids without a counter-selection marker. [PDF]
Most bacteria can only be transformed with circular plasmids, so robust DNA integration methods for these rely upon selection of single-crossover clones followed by counter-selection of double-crossover clones.
Cartman, ST +6 more
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Chicken MBD4 Regulates Immunoglobulin Diversification by Somatic Hypermutation
Immunoglobulin (Ig) diversification occurs via somatic hypermutation (SHM) and class switch recombination (CSR), and is initiated by activation-induced deaminase (AID), which converts cytosine to uracil.
Ryan Costello +2 more
doaj +1 more source
The molecular and crystal structures of the title compound, C4H4Cl2N2O3, were investigated by single-crystal X-ray diffraction and a Hirshfeld surface analysis.
Anton P. Novikov +4 more
doaj +1 more source
Cell Lysis in S. pombe ura4 Mutants Is Suppressed by Loss of Functional Pub1, Which Regulates the Uracil Transporter Fur4. [PDF]
Schizosaccharomyces pombe Δura4 cells lyse when grown on YPD medium. A S. pombe non-essential gene deletion library was screened to determine suppressors of the lysis phenotype.
Kohei Nishino +4 more
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