Results 201 to 210 of about 107,812 (233)

Synthesis of 5-styryl derivatives of uracil nucleosides and nucleotides.

Tetrahedron Letters, 1979
Abstract Uracil nucleosides and nucleotides undergo a palladium catalyzed coupling reaction with styrenes to yield the respective 5-substituted derivatives.
Mathias P Mertes
exaly   +2 more sources

Synthesis and potency of novel uracil nucleotides and derivatives as P2Y2 and P2Y6 receptor agonists [PDF]

Bioorganic and Medicinal Chemistry, 2008
The phosphate, uracil, and ribose moieties of uracil nucleotides were varied structurally for evaluation of agonist activity at the human P2Y(2), P2Y(4), and P2Y(6) receptors. The 2-thio modi.
Kenneth A Jacobson, Loredana Cappellacci, Sonia de Castro   +2 more
exaly   +4 more sources

Enzymatic formation of uracil and azauriail nucleotides in Streptococcus faecalis

Biochemical Pharmacology, 1966
Robert E Handschumacher, R E Handschumacher   +1 more
exaly   +3 more sources

The orphan receptor GPR17 identified as a new dual uracil nucleotides/cysteinyl-leukotrienes receptor

EMBO Journal, 2006
Nucleotides and cysteinyl-leukotrienes (CysLTs) are unrelated signaling molecules inducing multiple effects through separate G-protein-coupled receptors: the P2Y and the CysLT receptors.
Paolo Ciana, Claudia Verderio, Maria Letizia Trincavelli   +2 more
exaly   +3 more sources

Palladium-catalyzed coupling reactions of uracil nucleosides and nucleotides

Journal of the American Chemical Society, 1980
Mathias P Mertes
exaly   +2 more sources

Glomerular uracil nucleotide synthesis

American Journal of Physiology-Renal Physiology, 1988
The biosynthesis of basement membrane material requires the sugar derivatives of uridine 5'-triphosphate (UTP) for protein glycosylation. Uridine and orotate utilization for the biosynthesis of uracil ribonucleotides was studied in isolated rat glomeruli incubated in vitro. At a 1 microM concentration total orotate utilization was 9.6 +/- 1.8 pmol.min-
P, Cortes, F, Dumler, N W, Levin
openaire   +2 more sources

Acidity of a Nucleotide Base:  Uracil

The Journal of Physical Chemistry A, 2004
Experiment and calculations are used to show that the gas-phase acidity of uracil is comparable to that of HCl. The gas-phase acidity of uracil (denoted here by U) was bracketed by proton-transfer measurements involving Uand various reference acids (denoted here by A) of known gas-phase acidity.
Thomas M. Miller, Susan T. Arnold, A. A. Viggiano, Amy E. Stevens Miller   +3 more
openaire   +1 more source

P2 Receptors Activated by Uracil Nucleotides - An Update

Current Medicinal Chemistry, 2006
Pyrimidine nucleotides, including UTP, UDP and UDP-glucose, are important signaling molecules which activate G protein-coupled membrane receptors (GPCRs) of the P2Y family. Four distinct pyrimidine nucleotide-sensitive P2Y receptor subtypes have been cloned, P2Y2, P2Y4, P2Y6 and P2Y14. P2Y2 and P2Y4 receptors are activated by UTP (the P2Y2, and the rat
Andreas, Brunschweiger, Christa E, Müller   +1 more
openaire   +2 more sources

Bromination of nucleotides. Coulometric determination of cytosine, thymine, and uracil compounds

Analytical Chemistry, 1975
exaly   +3 more sources

Recognition of an Unnatural Difluorophenyl Nucleotide by Uracil DNA Glycosylase

Biochemistry, 2004
The DNA repair enzyme uracil DNA glycosylase (UDG) utilizes base flipping to recognize and remove unwanted uracil bases from the genome but does not react with its structural congener, thymine, which differs by a single methyl group. Two factors that determine whether an enzyme flips a base from the duplex are its shape and hydrogen bonding properties.
Yu Lin, Jiang, Lynda M, McDowell, Barbara, Poliks, Daniel R, Studelska, Chunyang, Cao, Gregory S, Potter, Jacob, Schaefer, Fenhong, Song, James T, Stivers   +8 more
openaire   +2 more sources