Results 81 to 90 of about 38,184 (196)
Urate and p-aminohippurate transport in rat renal basolateral vesicles
, 1985 We examined the transport of urate in basolateral membrane vesicles from the rat kidney and determined the relationship between the transport of urate and p-aminohippurate (PAH).
H. Shelat, E. J. Weinman, A. M. Kahn
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MarR homologs with urate-binding signature [PDF]
, 2011 Bacteria that associate with living hosts require intricate mechanisms to detect and respond to host defenses. Part of the early host defense against invading bacteria is the production of reactive oxygen species, and xanthine oxidase is one of the main ...
Anne Grove +3 more
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ABCG2 polymorphisms in gout: insights into disease susceptibility and treatment approaches
Pharmacogenomics and Personalized Medicine, 2017 MC Cleophas,1,2 LA Joosten,1–3 LK Stamp,4 N Dalbeth,5 OM Woodward,6 Tony R Merriman7 1Department of Internal Medicine, 2Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, the Netherlands; 3Department of ...
Cleophas MC +5 more
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The FEBS Journal, EarlyView.Using 1H NMR metabolomics, we measured polar and lipid metabolites from human blood neutrophils from people with frailty (n = 31, mean age 84Y), people with rheumatoid arthritis (n = 16, mean age 55Y), robust older (n = 24, mean age 66Y) and healthy younger people (n = 21, mean age 22Y).
Genna Ali Abdullah +5 more
wiley +1 more source
Urate reabsorption in proximal convoluted tubule of the rat kidney
, 1976 Urate reabsorption was examined in the rat utilizing clearance and in vivo microperfusion techniques. In control rats, the fractional excretion of urate averaged 12.5 +/- 1.3% of the filtered load, with 60-70% of perfused urate reabsorbed at 2 mm of ...
EJ Weinman +3 more
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Comment on: use of blood biomarkers to screen for obstructive sleep apnea
Nature and Science of Sleep, 2018 Burton Abrams Zeger-Abrams Inc., Elkins Park, PA, USAThe recently published paper in Nature and Science of Sleep1 describes a combination of blood biomarkers for obstructive sleep apnea (OSA) screening which is shown to have better sensitivity and ...
Abrams B
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Treatment strategies for interstitial granulomatous dermatitis: Systematic review and expert opinion
Journal of the European Academy of Dermatology and Venereology, EarlyView.Systematic review of 108 studies with a total of 182 patients with interstitial granulomatous dermatitis (IGD). IGD was frequently associated with systemic conditions or drug exposure. Management includes careful medication review and prompt withdrawal of potential triggers. Corticosteroids (systemic and topical) were commonly effective, while biologic
Francesco Bellinato +4 more
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LABOUR, EarlyView.ABSTRACT This study examines a neglected aspect of industrial relations: workplace disputes in which workers are incidentally made idle because of strike actions of others. These spillover effects have received little systematic attention despite potentially accounting for a substantial share of the employment consequences of industrial conflict.
Robert A. Hart, Carl Singleton
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The Journal of Physiology, EarlyView.Abstract figure legend The calcium‐activated chloride (ClCa) channel TMEM16A (also known as ANO1) plays critical roles in ion transport, neurotransmission and smooth muscle contraction. Dysregulation of TMEM16A channel activity contributes to the development and progression of various diseases.
Hisao Yamamura +4 more
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Journal of Rheumatic DiseasesHyperuricemia is highly prevalent in patients with chronic kidney disease (CKD) due to reduced renal urate clearance, which leads to an increased incidence of gout in this population.
Yoon-Jeong Oh +3 more
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