Results 71 to 80 of about 5,281 (177)
Battle of the strategies: diet versus drug therapy for gout
Современная ревматологияThe best results in combating gout are achieved through a combination of diet and drug therapy. Urate-lowering therapy, which includes febuxostat, has been shown to be more effective and convenient than diet when it comes to achieving and maintaining ...
O. V. Zhelyabina +2 more
doaj +1 more source
Practical application of national clinical guidelines for the management of gout (preliminary data)
Современная ревматология, 2020 The 2018 national guidelines for the management of gout provide a consistent scheme for urate-lowering drugs; however, the possibility of achieving uric acid (UA) targets in its use has not been studied.Objective: to evaluate the effectiveness and safety
M. N. Chikina +2 more
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The NLRP3 Inflammasome: Mechanisms of Activation, Regulation, and Therapeutic Opportunities
MedComm, Volume 7, Issue 3, March 2026.Diverse diseases converge on NLRP3. We depict a discovery‐to‐clinic track: high‐throughput/phenotypic screens, structure‐guided design, and modality innovation (allosteric inhibitors, interface blockers, degraders) deliver third‐generation, disease‐tailored NLRP3 control.
Chan Zou +5 more
wiley +1 more source
Zhongguo shuxue zazhi[Objective] To evaluate the efficacy and safety of the single-use hemoperfusion device (UA230) in treating refractory gout (RG) via plasma perfusion. [Methods] Thirty-four RG patients aged 18-65 years were recruited and randomly divided into a control ...
LI Ying +6 more
doaj +1 more source
New Zealand Journal of Botany, Volume 64, Issue 1, March 2026.Central Asia harbors a rich yet understudied assemblage of wood‐inhabiting Hymenochaetoid fungi. This review delivers the first comprehensive synthesis of 43 poroid species representing 18 genera documented across montane forests, steppes, and xeric habitats.
Yusufjon Gafforov +16 more
wiley +1 more source
Treatment approaches and adherence to urate-lowering therapy for patients with gout
Patient Preference and Adherence, 2017 Thanda Aung,* Gihyun Myung,* John D FitzGerald Division of Rheumatology/Department of Internal Medicine, University of California, Los Angeles, Los Angeles, CA, USA *These authors contributed equally to this work Abstract: Gout is the most common ...
Aung T, Myung G, FitzGerald JD
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Nephrology, Volume 31, Issue 3, March 2026.The study investigated allopurinol dosing practises and serum urate concentrations in gout patients with kidney failure following commencing dialysis. Results showed allopurinol dose was most commonly 100 mg, unadjusted upon commencing dialysis. However, serum urate concentrations significantly declined as patients commenced dialysis with more than 50%
Noha Kamel +6 more
wiley +1 more source
Drug Design, Development and Therapy, 2017 Graeme Jones,1 Elena Panova,1 Richard Day2 1Menzies Institute for Medical Research, University of Tasmania, Hobart, TAS, Australia; 2University of New South Wales, Medicine, St Vincent’s Hospital, Sydney, NSW, Australia Abstract: The aim of this ...
Jones G, Panova E, Day R
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Treatment of Gout in Patients with CrCl ≤30 mL/min and/or on Hemodialysis: A Review
RheumatoGout is highly prevalent in patients with chronic kidney disease (CKD) and end-stage renal disease (ESRD), owing to impaired uric acid excretion. However, treating gout in this population is challenging due to concerns about medication safety and ...
Fares Saliba +10 more
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Impact of pegloticase on patient outcomes in refractory gout: current perspectives
Open Access Rheumatology: Research and Reviews, 2018 Rita N Cunha,1 Renata Aguiar,1 Filipa Farinha2 1Rheumatology Department, Centro Hospitalar do Baixo Vouga, Aveiro, Portugal; 2Centre for Rheumatology, University College London, London, UK Abstract: Gout is currently the most frequent cause of ...
Cunha RN, Aguiar R, Farinha F
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