Results 11 to 20 of about 2,310,068 (246)

Urea Cycle and Arginine Metabolic Changes in COVID-19 Patients

open access: yesEurasian Journal of Emergency Medicine, 2023
Aim:Metabolic changes begin after the invasion of an infectious microorganism and continue to develop as a series of interrelated events. Arginine is important in infectious diseases due to lymphocyte proliferation, nitricoxide production by macrophages,
Sedat Özbay   +7 more
doaj   +2 more sources

Profile of sodium phenylbutyrate granules for the treatment of urea-cycle disorders: patient perspectives

open access: yesPatient Preference and Adherence, 2017
Luis Peña-Quintana,1–3 Marta Llarena,2 Desiderio Reyes-Suárez,2 Luis Aldámiz-Echevarria4 1Pediatric Gastroenterology, Hepatology, and Nutrition Unit, Universitario Materno-Infantil Hospital de Canarias, University of Las ...
Peña-Quintana L   +3 more
doaj   +3 more sources

Hydrogen from urea: a novel energy source [PDF]

open access: yes, 2011
This research presents a viability assessment of using urea as an energy vector. Urea is attractive in comparison to the chemicals previously considered for supplying hydrogen since it is non-toxic, non-flammable and stable at room temperature and ...
Rollinson, Andrew Neil
core   +6 more sources

Supporting your practice: Compounding sodium benzoate oral liquid for urea cycle disorders

open access: yes, 2021
Urea cycle disorders (UCD) are rare inherited metabolic disorders with an incidence estimated to be 1: 35,000 births. UCDs are caused by the dysfunction of any of the six enzymes (namely, carbamoyl phosphate synthetase I, N-acetylglutamate synthetase ...
Haywood, Alison, Glass, Beverley
core   +1 more source

Extension of Generic Amyloid Hypothesis to Metabolites of Urea Cycle and Uric Acid pathway [PDF]

open access: yes, 2022
Herein, we report the aggregation properties of metabolites of urea cycle and uric acid pathway. The aggregation/ self-assembly properties of these metabolites were studied extensively via microscopic techniques.
Monisha, Patel   +5 more
core   +1 more source

Nicotinamide prevention in diabetes-induced alterations in the rat liver

open access: yesEndocrine Regulations, 2023
Objective. The study was performed to elucidate whether nicotinamide (NAm) can attenuate the diabetes-induced liver damage by correction of ammonia detoxifying function and disbalance of NAD-dependent processes in diabetic rats.
Kuchmerovska Tamara   +5 more
doaj   +1 more source

The Role of Urea Cycle Functional Studies in Preclinical Research. [PDF]

open access: yesJ Inherit Metab Dis
Inborn errors of metabolism affecting the urea cycle are rare severe conditions caused by impaired nitrogen detoxification, leading to hyperammonemia and neurological morbidity across a broad clinical spectrum.
Breuillard N   +5 more
europepmc   +2 more sources

Genetics of enzymatic dysfunctions in metabolic disorders and cancer

open access: yesFrontiers in Oncology, 2023
Inherited metabolic disorders arise from mutations in genes involved in the biogenesis, assembly, or activity of metabolic enzymes, leading to enzymatic deficiency and severe metabolic impairments.
Mélanie Mahé   +3 more
doaj   +1 more source

Urinary phenylacetylglutamine (U-PAGN) concentration as biomarker for adherence in patients with urea cycle disorders (UCD) treated with glycerol phenylbutyrate

open access: yesMolecular Genetics and Metabolism Reports, 2015
Urinary phenylacetylglutamine (U-PAGN) concentrations in spot urine samples were analyzed as a dosing biomarker during glycerol phenylbutyrate (GPB) dosing in 68 healthy adults and 66 adult and pediatric patients with urea cycle disorders who ...
M. Mokhtarani   +11 more
doaj   +1 more source

Protein and calorie intakes in adult and pediatric subjects with urea cycle disorders participating in clinical trials of glycerol phenylbutyrate

open access: yesMolecular Genetics and Metabolism Reports, 2016
Background: Little prospectively collected data are available comparing the dietary intake of urea cycle disorder (UCD) patients to UCD treatment guidelines or to healthy individuals.
Debra Hook   +10 more
doaj   +1 more source

Home - About - Disclaimer - Privacy