Results 31 to 40 of about 2,310,068 (246)

Ornithine Transcarbamylase Deficiency in Iranian Children [PDF]

Iranian Journal of Public Health, 2003
Ammonia is a toxic material for mammalians. It is detoxificated and converted to urea in the urea cycle in liver. Each defect in the urea cycle cause increase in blood ammonia level.
HR Joshaghani, M Jalali, T Zaman   +2 more
doaj   +1 more source

Hepatocyte-Specific Knock-Out of Nfib Aggravates Hepatocellular Tumorigenesis via Enhancing Urea Cycle

Frontiers in Molecular Biosciences, 2022
Nuclear Factor I B (NFIB) has been reported to promote tumor growth, metastasis, and liver regeneration, but its mechanism in liver cancer is not fully elucidated. The present study aims to reveal the role of NFIB in hepatocellular carcinogenesis. In our
Li Zhou, Qing-Liang Wang, Lin-Hong Mao, Lin-Hong Mao, Si-Yuan Chen, Zi-Han Yang, Xue Liu, Yu-Hua Gao, Xiao-Qin Li, Zhi-Hang Zhou, Song He   +10 more
doaj   +1 more source

Plasma urea cycle metabolite levels and the risk of moyamoya disease

Frontiers in Neuroscience, 2023
Background and purposeUrea cycle metabolites are expected to be the biomarkers for cerebrovascular diseases. However, the effects of circulating urea cycle metabolites on the risk of MMD and its subcategories remain unclear.
Xiaofan Yu, Xiaofan Yu, Xiaofan Yu, Xiaofan Yu, Xiaofan Yu, Peicong Ge, Peicong Ge, Peicong Ge, Peicong Ge, Peicong Ge, Yuanren Zhai, Yuanren Zhai, Yuanren Zhai, Yuanren Zhai, Yuanren Zhai, Wei Liu, Wei Liu, Wei Liu, Wei Liu, Wei Liu, Qian Zhang, Qian Zhang, Qian Zhang, Qian Zhang, Qian Zhang, Xun Ye, Xun Ye, Xun Ye, Xun Ye, Xun Ye, Xingju Liu, Xingju Liu, Xingju Liu, Xingju Liu, Xingju Liu, Rong Wang, Rong Wang, Rong Wang, Rong Wang, Rong Wang, Yan Zhang, Yan Zhang, Yan Zhang, Yan Zhang, Yan Zhang, Jizong Zhao, Jizong Zhao, Jizong Zhao, Jizong Zhao, Jizong Zhao, Jizong Zhao, Dong Zhang, Dong Zhang, Dong Zhang, Dong Zhang, Dong Zhang, Dong Zhang   +56 more
doaj   +1 more source

L-arginine metabolism in mitochondria isolated from the liver of Antarctic fish Notothenia rossii and Notothenia neglecta

Brazilian Archives of Biology and Technology, 2006
The arginase tissue distribution, the biochemical properties of the argininolytic system and the subcellular localization of the enzymes carbamoylphosphate synthetase, ornithinecarbamoyl transferase, glutamine synthetase and arginase in Antarctic fish, N.
Edson Rodrigues, Ana Cristina Miguez Teixeira Ribeiro, Metry Bacila   +2 more
doaj   +1 more source

Structural analysis and molecular substrate recognition properties of Arabidopsis thaliana ornithine transcarbamylase, the molecular target of phaseolotoxin produced by Pseudomonas syringae

Frontiers in Plant Science, 2023
Halo blight is a plant disease that leads to a significant decrease in the yield of common bean crops and kiwi fruits. The infection is caused by Pseudomonas syringae pathovars that produce phaseolotoxin, an antimetabolite which targets arginine ...
Maciej Nielipinski, Agnieszka J. Pietrzyk-Brzezinska, Alexander Wlodawer, Bartosz Sekula   +3 more
doaj   +1 more source

ABOUT PATHOPHYSIOLOGICAL THERAPY OF ASTHENIA IN CHILDREN BY CITRULLINE MALATE DRUGS

Медицинский совет, 2017
The article provides information about frequency of the asthenic syndrome in the pediatric practice. The optimal therapeutic approach solving a number of tasks is offered: elimination of the liver overload by nitrous slag, elimination of urea from ...
O. A. Gromova, I. N. Zakharova, I. Y. Torshin, T. R. Grishina, O. A. Limanova   +4 more
doaj   +1 more source

Effects of Dufulin on Oxidative Stress and Metabolomic Profile of Tubifex

Metabolites, 2021
Dufulin is a highly effective antiviral pesticide used in plants. In this study, a seven-day experiment was conducted to evaluate the effects of Dufulin at five different concentrations (1 × 10−4, 1 × 10−3, 1 × 10−2, 0.1, and 1 mg/L) on Tubifex.
Yile Yu, Yuxin Zhu, Jing Yang, Wentao Zhu, Zhiqiang Zhou, Renke Zhang   +5 more
doaj   +1 more source

The Neighboring Subunit Is Engaged to Stabilize the Substrate in the Active Site of Plant Arginases

Frontiers in Plant Science, 2020
Arginine acts as a precursor of polyamines in plants in two known pathways, agmatine and ornithine routes. It is decarboxylated to agmatine by arginine decarboxylase, and then transformed to putrescine by the consecutive action of agmatine iminohydrolase
Bartosz Sekula
doaj   +1 more source

Urea Finishing Process: Prilling versus Granulation [PDF]

, 2014
Solid urea is the largest nitrogen fertilizer product which is produced in two forms of granules and prills. Although the chemical properties of both prills and granules remain similar, their different physical and mechanical properties are ...
Naderi, Sina, Naderi, S., Hassanpour, Ali, Abbas, R., Hassanpour, A., Šupuk, Enes, Abbas, Rafid, Supuk, E., Rahmanian, Nejat, Supuk, E, Hassanpour, A, Rahmanian, N, Abbas, R, Naderi, S   +13 more
core   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source