Results 11 to 20 of about 1,080,434 (247)
Inhibition of Urease by Hydroquinones: A Structural and Kinetic Study [PDF]
AbstractHydroquinones are a class of organic compounds abundant in nature that result from the full reduction of the corresponding quinones. Quinones are known to efficiently inhibit urease, a NiII‐containing enzyme that catalyzes the hydrolysis of urea to yield ammonia and carbonate and acts as a virulence factor of several human pathogens, in ...
Luca Mazzei +2 more
core +7 more sources
Kinetics and Mechanism Study of Competitive Inhibition of Jack-Bean Urease by Baicalin [PDF]
Baicalin (BA) is the principal component of Radix Scutellariae responsible for its pharmacological activity. In this study, kinetics and mechanism of inhibition by BA against jack-bean urease were investigated for its therapeutic potential.
Lirong Tan +10 more
doaj +2 more sources
Inhibition of ruminal urease [PDF]
Rumen bacteria elaborate an enzyme, urease. Urease is capable of breaking down urea to ammonia and carbon dioxide. Rumen bacteria then incorporate the ammonia into new amino acids and bacterial protein. Thus, urea can be used as a non-nitrogen source
B.E. Brent +3 more
openaire +3 more sources
INVESTIGATION AND OPTIMIZATION OF REACTIVATION OF UREASE BIOSENSOR FOR HEAVY METALS INHIBITION ANALYSIS [PDF]
Research was aimed at the optimization of the urease biosensor for analysis of heavy metals and determining the opportunities of its reactivation. A differential pair of gold interdigitated electrodes deposited on a ceramic substrate was used as the ...
S. R. +5 more
doaj +2 more sources
BackgroundTreatment of Helicobacter pylori (H. pylori) infections is challenged by antibiotic resistance. The urease enzyme contributes to H. pylori colonization in the gastric acidic environment by producing a neutral microenvironment.
Hanaa Shaalan +3 more
doaj +2 more sources
Zerumbone Inhibits Helicobacter pylori Urease Activity [PDF]
Helicobacter pylori (H. pylori) produces urease in order to improve its settlement and growth in the human gastric epithelium. Urease inhibitors likely represent potentially powerful therapeutics for treating H.
Hyun Jun Woo +4 more
doaj +3 more sources
Fluoride inhibition of Sporosarcina pasteurii urease: structure and thermodynamics
Urease is a nickel-dependent enzyme and a virulence factor for ureolytic bacterial human pathogens, but it is also necessary to convert urea, the most worldwide used fertilizer, into forms of nitrogen that can be taken up by crop plants. A strategy to control the activity of urease for medical and agricultural applications is to use enzyme inhibitors ...
Benini, S. +3 more
openaire +4 more sources
Inhibition of Urease by Penicillin [PDF]
IN treating patients with penicillin, our interest has been attracted to the problem of assay of the drug. Difficulties in this connexion are attached to clinical as well as laboratory studies, since it would be of considerable assistance in formulating principles for therapy to be able to measure small, sub-bacteriostatic quantities in the circulating
JOSEPH C. TURNER +2 more
openaire +1 more source
Inhibitory Effect and Mechanism of Urease by Water-extracted Polyphenols in Dandelion
Water-extracted polyphenols in dandelion have been reported to possess a high potential for inhibit urease. Dandelion powder with whole grass was used to screen the main water-extracted polyphenols in dandelion with inhibiting urease, and study the ...
Ping WU, Yanni LI, Hui ZOU, Yilun CHEN
doaj +1 more source

