Results 31 to 40 of about 1,080,434 (247)

Coptisine-induced inhibition of Helicobacter pylori: elucidation of specific mechanisms by probing urease active site and its maturation process

open access: yesJournal of Enzyme Inhibition and Medicinal Chemistry, 2018
In this study, we examined the anti-Helicobactor pylori effects of the main protoberberine-type alkaloids in Rhizoma Coptidis. Coptisine exerted varying antibacterial and bactericidal effects against three standard H.
Cailan Li   +11 more
doaj   +1 more source

Irreversible Inhibition of Jack Bean Urease by Pyrocatechol [PDF]

open access: yesJournal of Enzyme Inhibition and Medicinal Chemistry, 2003
Pyrocatechol was studied as an inhibitor of jack bean urease in 20 mM phosphate buffer, pH 7.0, 25 degrees C. The inhibition was monitored by an incubation procedure in the absence of substrate and reaction progress studies in the presence of substrate. It was found that pyrocatechol acted as a time- and concentration dependent irreversible inactivator
Kot, Mirosława, Zaborska, Wiesława
openaire   +3 more sources

Inhibition of the urea‑urease reaction by the components of the zeolite imidazole frameworks‑8 and the formation of urease‑zinc‑imidazole hybrid compound [PDF]

open access: yes, 2022
In the past decade, much effort has been devoted to using chemical clock-type reactions in material design and driving the self-assembly of various building blocks. Urea-urease enzymatic reaction has chemical pH clock behavior in an unbuffered medium, in
Miele Ylenia   +22 more
core   +3 more sources

Role of ureolytic activity in Bacillus cereus nitrogen metabolism and acid survival [PDF]

open access: yes, 2008
The presence and activities of urease genes were investigated in 49 clinical, food, and environmental Bacillus cereus isolates. Ten strains were shown to have urease genes, with eight of these strains showing growth on urea as the sole nitrogen source ...
Abee, T., Mols, J.M.
core   +1 more source

DETERMINATION OF THE OPTIMUM CONDITIONS FOR UREASE INHIBITTION EXTRACTED FROM SOME LOCAL PLANTS

open access: yesThe Iraqi Journal of Agricultural science, 2021
In the current study, four types of plants commonly used namely Soybean, chickpea, bean, pea were obtained and screened for urease activity, among this plants, chickpea was chosen with maximum enzymatic activity, and it had the highest productivity of ...
Hussein & et al.
doaj   +1 more source

Molecular docking, synthesis, kinetics study, structure–activity relationship and ADMET analysis of morin analogous as Helicobacter pylori urease inhibitors

open access: yesBMC Chemistry, 2019
Background Urease are responsible for several pathogenic states in human as well as in animals and its inhibition is utmost urgent. Clinically used drugs are associated with many side effects; recently several researches have shown that flavonoids have ...
Ritu Kataria, Anurag Khatkar
doaj   +1 more source

α-glucosidase and urease inhibition assays of four solvent extracts of T. neotaliala.

open access: yes, 2022
α-glucosidase and urease inhibition assays of four solvent extracts of T. neotaliala.
Huma Rao (9389397)   +6 more
core   +1 more source

Synthesis of novel cyanoacetamides derivatives and their urease inhibition studies [PDF]

open access: yes, 2015
The present study reports a convenient approach for the synthesis of cyanoacetamide based derivatives (7-27) via two-step process involving Knoevenagel reaction, followed by three component reaction to avail desired compounds.
Nasim, Faiz-ul Hassan   +4 more
core   +1 more source

Inhibition of urease activity in soils

open access: yesSoil Biology and Biochemistry, 1971
Studies to evaluate more than 100 compounds as inhibitors of urease activity in soils showed that dihydric phenols and quinones were the most effective organic compounds tested and that silver and mercury salts were the most effective inorganic compounds.
J.M. Bremner, L.A. Douglas
openaire   +4 more sources

Stabilizing Functional Nucleic Acids for Real‐Sample Diagnostics

open access: yesAngewandte Chemie, EarlyView.
Functional nucleic acids enable programmable real‐sample diagnostics, but often lose function in complex biological matrices. This review highlights four stabilization levers—chemical, topological, architectural, and microenvironment/interface engineering—that preserve aptamer and DNAzyme performance in saliva, serum, urine, and stool, reframing ...
Soyeon Lee   +4 more
wiley   +2 more sources

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