Results 21 to 30 of about 1,080,434 (247)

Urease-Immobilized PEI Cryogels for the Enzymatic Hydrolysis of Urea and Carbon Dioxide Uptake

open access: yes, 2022
Here, the immobilization of the urease enzyme within polyethyleneimine (PEI) cryogels (Urease@PEI cryogel) is reported during the synthesis via the entrapment method. The immobilization yield of the enzymes within PEI cryogels was determined as >85%, and
Nurettin Sahiner (3624755)   +3 more
core   +1 more source

Inhibition of urease by some new synthesized 1,2,4-triazol derivatives: Inhibition mechanism and molecular docking [PDF]

open access: yes, 2019
Urease is a metalloenzyme that catalyzes the hydrolysis of urea to ammonia and carbon dioxide. This ammonia secretion may cause significant increase in pH and is responsible for negative effects of urease activity in human health and agriculture.
ÇOLAK, AHMET   +4 more
core   +3 more sources

Synthesis, spectroscopic characterization and pharmacological evaluation of oxazolone derivatives [PDF]

open access: yesJournal of the Serbian Chemical Society, 2013
A series of 4-aryl methylidene-2-phenyl/methyl-5-(4H)-oxazolone derivatives (2-7) have been synthesized using the reported method by condensation of aldehydes with N-benzoyl / N-acetyl glycine in the presence of zinc oxide as a catalyst and acetic ...
Fareed Ghulam   +7 more
doaj   +1 more source

Explaining Urease Specificity Towards Nickel: A Re-Analysis of Its Proposed Mechanism [PDF]

open access: yes, 2020
Urease is a binuclear metalloenzyme selective towards nickel, exhibiting a remarkable rate enhancement of the catalytic reaction. The accepted mechanism for urease describes the coordination of urea to both nickel centers in an O,N bridged mode ...
Caio Bezerra de, Castro   +2 more
core   +1 more source

Exploring the potential of propanamide-sulfonamide based drug conjugates as dual inhibitors of urease and cyclooxygenase-2: biological and their in silico studies

open access: yesFrontiers in Chemistry, 2023
Derivative synthesis has been a crucial method for altering the effects of already-approved medications, especially to lessen adverse effects and enhance results.
Saghir Ahmad   +9 more
doaj   +1 more source

The results of urease inhibition assay of meropenem and its derivatives.

open access: yes, 2022
The results of urease inhibition assay of meropenem and its derivatives.
Mohsin Abbas Khan (14305173)   +5 more
core   +1 more source

Synthesis of N-(6-Arylbenzo[d]thiazole-2-acetamide Derivatives and Their Biological Activities: An Experimental and Computational Approach

open access: yesMolecules, 2016
A new series of N-(6-arylbenzo[d]thiazol-2-yl)acetamides were synthesized by C-C coupling methodology in the presence of Pd(0) using various aryl boronic pinacol ester/acids.
Yasmeen Gull   +9 more
doaj   +1 more source

Characteristics of thirteen soils used in urease inhibition assay using plant extracts.

open access: yes, 2021
Characteristics of thirteen soils used in urease inhibition assay using plant extracts.
Rashid Mahmood (10717140)   +2 more
core   +1 more source

Screening and Identification of Herbal Urease Inhibitors Using Surface Plasmon Resonance Biosensor [PDF]

open access: yesResearch Journal of Pharmacognosy, 2021
Background and objectives: Urease, that catalyzes the hydrolysis of urea, has received substantial attention for its impact on living organisms’ health and human life quality.
Mahmood Biglar   +6 more
doaj   +1 more source

Inhibition of Urease by Disulfiram, an FDA-Approved Thiol Reagent Used in Humans

open access: yesMolecules, 2016
Urease is a nickel-dependent amidohydrolase that catalyses the decomposition of urea into carbamate and ammonia, a reaction that constitutes an important source of nitrogen for bacteria, fungi and plants.
Ángel Gabriel Díaz-Sánchez   +8 more
doaj   +1 more source

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