Results 21 to 30 of about 5,112,493 (265)
SGLT2 Inhibition and Uric Acid Excretion in Patients with Type 2 Diabetes and Normal Kidney Function
American Society of Nephrology. Clinical Journal, 2022 Visual Abstract Background and objectives Sodium-glucose transporter 2 (SGLT2) inhibitor–induced uric acid lowering may contribute to kidney-protective effects of the drug class in people with type 2 diabetes. This study investigates mechanisms of plasma
Danii L. S. Suijk +12 more
semanticscholar +1 more source
Association of Uric Acid–Lowering Therapy With Incident Chronic Kidney Disease
JAMA Network Open, 2022 Key Points Question What is the association of uric acid–lowering therapy with the development of new onset chronic kidney disease (CKD)? Findings In this cohort study of 269 651 patients with estimated glomerular filtration rate of at least 60 mL/min/1 ...
Waleed Hassan +9 more
semanticscholar +1 more source
Children, 2023 Background: Studies have shown that serum uric acid levels and uric acid-related ratios, such as uric acid-to-albumin ratio (UAR), uric acid-to-creatinine ratio (UCR), uric acid-to-high-density lipoprotein cholesterol (HDL cholesterol) ratio (UHR), and ...
Okan Dikker +4 more
doaj +1 more source
Engineering Escherichia coli for diagnosis and management of hyperuricemia
Frontiers in Bioengineering and Biotechnology, 2023 Uric acid disequilibrium is implicated in chronic hyperuricemia-related diseases. Long-term monitoring and lowering of serum uric acid levels may be crucial for diagnosis and effective management of these conditions.
Gozde Gencer +6 more
doaj +1 more source
The Good, the Bad and the New about Uric Acid in Cancer
Cancers, 2022 Simple Summary The concentration of uric acid in blood is sex-, age- and diet-dependent and is maintained close to its maximal solubility, indicating that it plays some important role.
S. Allegrini +4 more
semanticscholar +1 more source
Uric Acid in Inflammation and the Pathogenesis of Atherosclerosis
International Journal of Molecular Sciences, 2021 Hyperuricemia is a common metabolic syndrome. Elevated uric acid levels are risk factors for gout, hypertension, and chronic kidney diseases. Furthermore, various epidemiological studies have also demonstrated an association between cardiovascular risks ...
Y. Kimura, D. Tsukui, H. Kono
semanticscholar +1 more source
Revista da Associação Médica Brasileira, 2021 OBJECTIVE Non-alcoholic fatty liver disease, which is characterized by lipid being deposited into hepatocytes, affects nearly one in three adults globally. Inflammatory markers were suggested to be related with hepatic steatosis.
Mehmet Ali Kosekli +7 more
semanticscholar +1 more source
Serum uric acid in smokers [PDF]
المجلة العراقية للصيدلة, 2010 Objectives: To demonstrate the possible effect of smoking on serum uric acid level. Methods: The study was conducted during the period from March to June 2008 in Mosul city as a case control study.
Bassam E Hanna +2 more
doaj +1 more source
Scientific Reports, 2021 Uric acid has both antioxidant and pro-oxidant properties in vitro by scavenging and production of reactive oxygen species (ROS). This cross-sectional study examined whether uric acid possesses effects on oxidative stress under physiological conditions ...
Masafumi Kurajoh +13 more
semanticscholar +1 more source
Biomedicines, 2023 Several studies have showed that hyperuricemia is related to the development of ischemic heart disease (IHD). There is also growing evidence indicating that hyperuricemia may contribute to the progression of IHD as a pathogenic factor.
Sung-Bum Lee +4 more
doaj +1 more source