Results 31 to 40 of about 5,112,493 (265)

The Role of the Intestine in the Development of Hyperuricemia

open access: yesFrontiers in Immunology, 2022
Gout is a common inflammatory arthritis caused by the deposition of sodium urate crystals in the joints. Hyperuricemia is the fundamental factor of gout.
Hui Yin   +5 more
doaj   +1 more source

Hyperuricemia causes pancreatic β-cell death and dysfunction through NF-κB signaling pathway. [PDF]

open access: yesPLoS ONE, 2013
Accumulating clinical evidence suggests that hyperuricemia is associated with an increased risk of type 2 diabetes. However, it is still unclear whether elevated levels of uric acid can cause direct injury of pancreatic β-cells.
Lu Jia   +11 more
doaj   +1 more source

Serum uric acid level predicts the progression of amyotrophic lateral sclerosis following treatment with edaravone

open access: yesRedox Report, 2022
Introduction Uric acid and edaravone might exert a neuroprotective effect in amyotrophic lateral sclerosis (ALS) by reducing oxidative stress. We analyzed whether the treatment effect of edaravone is pronounced in patients whose uric acid level increased
Hee Jo Han   +4 more
doaj   +1 more source

Are Uric Acid Level and Uric Acid/Creatinine Ratio Reliable Biomarkers for Idiopathic Parkinson’s Disease Severity?

open access: yesHaseki Tıp Bülteni, 2020
Aim:It has been proposed that elevated levels of uric acid (UA) has a protective effect against the development of Idiopathic Parkinson’s Disease (IPD), however, since IPD has been found to be more common in gout patients, their relationship became ...
Vasfiye Burcu Albay, Mesude Tütüncü
doaj   +1 more source

Correlation of Serum Uric Acid and Serum Uric Acid/Creatinine Ratio Levels with Adverse Pregnancy Outcomes in Late Pregnancy [PDF]

open access: yesZhongguo quanke yixue
Background The disorder of serum uric acid metabolism during pregnancy is associated with adverse pregnancy outcomes, while few studies have analyzed and compared the correlation of serum uric acid and serum uric acid/creatinine ratio levels with adverse
ZHAO Ru, HAN Chen, HUANG Zeyu, WANG Qian, HU Jun, GE Zhijuan, BI Yan, SHEN Shanmei
doaj   +1 more source

Glucose Transporter 9 (GLUT9) Plays an Important Role in the Placental Uric Acid Transport System

open access: yesCells, 2022
Background: Hyperuricemia is a common laboratory finding in pregnant women compromised by preeclampsia. A growing body of evidence suggests that uric acid is involved in the pathogenesis of preeclampsia.
Benjamin P. Lüscher   +4 more
doaj   +1 more source

Uric Acid and Cardiovascular Disease: An Update From Molecular Mechanism to Clinical Perspective

open access: yesFrontiers in Pharmacology, 2020
Uric acid (UA) is the end product of purine nucleotide metabolism in the human body. Hyperuricemia is an abnormally high level of UA in the blood and may result in arthritis and gout.
Wei Yu, Jidong Cheng
semanticscholar   +1 more source

Estimation of urinary stone composition by automated processing of CT images [PDF]

open access: yesUrological Research (2009) epub ahead of print, 2009
The objective of this article was developing an automated tool for routine clinical practice to estimate urinary stone composition from CT images based on the density of all constituent voxels. A total of 118 stones for which the composition had been determined by infrared spectroscopy were placed in a helical CT scanner.
arxiv   +1 more source

Optical monitoring of hemodialysis using noninvasive measurement of uric acid in the dialysate

open access: yesScientific Reports, 2023
The aim of this study was to present a methodology for predicting changes in uric acid concentrations in the blood of chronically hemodialyzed patients based on an optical measurement of the intensity of selected wavelengths in the dialysate.
Wojciech Żyłka   +8 more
doaj   +1 more source

J-Shaped Relationship of Serum Uric Acid with Unfavorable Short-Term Outcomes among Patients with Acute Ischemic Stroke

open access: yesBiomedicines, 2022
(1) Background: The role of uric acid in stroke outcomes remains inconclusive. (2) Methods: We retrospectively enrolled 3370 patients with acute ischemic stroke. (3) Results: Uric acid level was higher in men than in women.
Chih-Yang Liu   +5 more
doaj   +1 more source

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