Results 71 to 80 of about 5,236,042 (380)
Uric acid, an important screening tool to detect inborn errors of metabolism: a case series
BMC Research Notes, 2017 Background Uric acid is the metabolic end product of purine metabolism in humans. Altered serum and urine uric acid level (both above and below the reference ranges) is an indispensable marker in detecting rare inborn errors of metabolism.
Eresha Jasinge +10 more
doaj +1 more source
Uric Acid is independently associated with diabetic kidney disease: a cross-sectional study in a Chinese population. [PDF]
PLoS ONE, 2015 Association between hyperuricaemia and chronic kidney disease has been studied widely, but the influence of uric acid on the kidneys remains controversial.
Dandan Yan +10 more
doaj +1 more source
Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes
Advanced Functional Materials, EarlyView.Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth +2 more
wiley +1 more source
Effect of Atorvastatin Alone and in Combination with Aspirin on Uric Acid Handling of Normal Rats
Proceedings, 2021 Introduction: Low doses of aspirin and statins are usually given in conjunction to patients with coronary artery disease. Aspirin at low doses is known to cause hyperuricemia in these patients which can further worsen their condition, while statins can ...
Usman Aslam +4 more
doaj +1 more source
Uric acid enhances longevity and endurance and protects the brain against ischemia [PDF]
, 2020 Among mammals, there is a positive correlation between serum uric acid (UA) levels and life span. Humans have high levels of UA because they lack a functional urate oxidase (UOX) enzyme that is present in shorter lived mammals.
Argüelles Castilla, Sandro +6 more
core +1 more source
Kidney Stone Dissolution By Tetherless, Enzyme‐Loaded, Soft Magnetic Miniature Robots
Advanced Healthcare Materials, EarlyView.Wireless magnetic robots are developed for kidney stone dissolution. The robots navigate through a urinary tract model from bladder and ureter to renal pelvis with the help of external magnetic fields. The filaments are loaded with urease enzyme which catalyzes urea to carbon dioxide and ammonia, thereby increasing pH to basic regime and supporting ...
Afarin Khabbazian +15 more
wiley +1 more source
Progress in research on uric acid metabolism pathway
Linchuang shenzangbing zazhi, 2019 Uric acid is a product of sputum metabolism, and its crease is caused by increase in uric acid production and a decrease in uric acid excretion. The main metabolic pathway of uric acid is present in the kidney, and secondly in the intestine; and the ...
HU Xiao-hua, ZHANG Li-ming
doaj
Simple and Rapid Method for the Determination of Uric Acid-Independent Antioxidant Capacity
Molecules, 2011 Determination of the relative contribution of uric acid level increases to the total measured antioxidative activity could be very useful for testing antioxidative products and their effect on human health.
Darko Modun +3 more
doaj +1 more source
Roll‐To‐Roll Production of Smart Dressings for Wound Monitoring
Advanced Healthcare Materials, EarlyView.This study presents a roll‐to‐roll manufactured smart wound dressing capable of visually monitoring key wound biomarkers, including pH, humidity, and temperature. By integrating colorimetric sensors into flexible dressing substrates, the device offers real‐time, equipment‐free insights for infection detection and wound management, representing a ...
Ziheng Wang +14 more
wiley +1 more source
Rheumatology, 2010 Uric acid (UA) is the end product of purine metabolism in humans due to the loss of uricase activity by various mutations of its gene during the Miocene epoch, which led to humans having higher UA levels than other mammals. Furthermore, 90% of UA filtered by the kidneys is reabsorbed, instead of being excreted.
Bonifacio Álvarez-Lario +1 more
openaire +3 more sources