Results 171 to 180 of about 114,454,660 (263)

Efficacy and Safety of Oral Non‐Statin Lipid‐Lowering Therapies in Dyslipidaemia: A Systematic Review and Network Meta‐Analysis

Endocrinology, Diabetes &Metabolism, Volume 9, Issue 6, November 2026.
A network meta‐analysis of 43 randomized trials showed that oral combination therapies, particularly obicetrapib plus ezetimibe and bempedoic acid plus ezetimibe, achieved the greatest LDL‐C reduction with reassuring safety profiles, supporting their use as effective oral alternatives for patients with dyslipidaemia. ABSTRACT Introduction Dyslipidaemia
Tamer Hodrob, Reem J. Saad, Aya Hamdy, Mariam Saleh Alheneedy, Ahmed Mohamed Shehata Abdelfattah Elsayed, Elsaghir Ghazy, Hazem Ayesh   +6 more
wiley   +1 more source

The role of the gut microbiota-uric acid metabolism axis in high-altitude hyperuricemia: dysregulation mechanisms, pathway associations and therapeutic perspectives. [PDF]

Front Microbiol
Shi C, Li L, Ge W, Gao Y, Li Y, Li W, Liu J.   +6 more
europepmc   +1 more source

Multiwalled Carbon Nanotube/Carbon Paste‐Modified Graphite Sheet Electrode Using Uric Acid as a Naturally Occurring Redox‐Active Molecule for Aptamer‐Mediated Signal Transduction

Electroanalysis, Volume 38, Issue 11, November 2026.
This study examines the use of uric acid (UA), a naturally occurring redox‐active molecule, as a reporter for aptamer‐mediated electrochemical signal transduction. Five graphite‐sheet electrode configurations were compared, with the multiwalled carbon nanotube/carbon paste‐modified graphite sheet electrode (MWCNT/CP/GSE) providing the strongest overall
Jixin Shang, Zhuoya Liao, Qianxi Zhao, Huizi Zhang, Toru Nohgi, Jun Kameoka   +5 more
wiley   +1 more source

The Human Urate Transportosome: Evolutionary Dynamics, Molecular Mechanisms, and Pharmacogenetic Perspectives. [PDF]

Med Sci (Basel)
Dzhemileva LU, D'yakonov VA, Marshala SN, Khusnutdinova E, Deviatkin AA, Shipulin GA.   +5 more
europepmc   +1 more source

Plant‐Derived Probiotics From Fermented Foods: Current Evidence on Antiviral Mechanisms and Gut–Lung Axis Modulation

Food Frontiers, Volume 7, Issue 6, November 2026.
Plant‐derived probiotics from fermented foods exert anti‐respiratory virus effects via immune regulation, antiviral metabolites, and gut–lung axis, highlighting their advantages, key technologies, and application prospects. ABSTRACT Respiratory viral infections represent a major global public health threat, causing widespread morbidity, mortality, and ...
Yinghao Xing, Yaoyuan Hu, Yingying Ma, Peng Yao, Jingjing Jiang, Jiao Guo, Shuangmei Liu   +6 more
wiley   +1 more source

Mechanistic Study on the Therapeutic Effects of Juanbi Lijieqing Formula in a Rat Model of Gouty Arthritis with Hyperuricemia

Journal of Pain Research
Yifan Lu,1– 3,* Chengyin Lu,1– 3,* Gonghui Jian,2 Hui Xiong,1– 3 Yang Shu1,2 1Orthopedics Department, The First Affiliated Hospital of Hunan University of Chinese Medicine, Changsha, Hunan, 410000, People’s Republic of China; 2Graduate ...
Lu Y, Lu C, Jian G, Xiong H, Shu Y
doaj  

Oral L-carnitine supplementation lowers serum uric acid and is associated with renal and intestinal urate-handling responses in hyperuricemic mice. [PDF]

Front Nutr
Jin F, Huang Y, Zhang F, He J, Zheng J, Jiang M, Jiao J, Zhao Y, Liu J, Zhang J, Wang L.   +10 more
europepmc   +1 more source

Dietary Interventions May Mitigate Health Risks of Per‐ and Polyfluoroalkyl Substances (PFAS) Exposure Through Modulation of the Gut Microbiota: A Review

Food Frontiers, Volume 7, Issue 6, November 2026.
Dietary interventions, including probiotics, prebiotics, and synbiotics, may modulate gut microbiota to regulate PFAS accumulation and elimination. Specific microbial taxa facilitate PFAS removal through adsorption and bioaccumulation, potentially reducing internal PFAS burden and mitigating PFAS‐related health risks.
Jiahui Xia, Xueqing Li, Mingluan Xing, Huixia Niu, Lizhi Wu, Xin Gong, Longxiao Liu, Zhijian Chen, Xiaoming Lou, Pengcheng Tu   +9 more
wiley   +1 more source

Glycemic burden-adjusted urinary glucose excretion deficit is associated with hyperuricemia in patients with type 2 diabetes. [PDF]

Front Endocrinol (Lausanne)
Wang L, Wang Y, Gong Y, Geng H.
europepmc   +1 more source

Gene‐Guided Therapy in Type 2 Diabetes Mellitus: An Integrative Review of the Pharmacogenetics of Metformin and Sodium‐Glucose Cotransporter‐2 Inhibitors [PDF]

Endocrinol Diabetes Metab
Genetic variation influences the pharmacological response to metformin and SGLT2 inhibitors in patients with type 2 diabetes mellitus. Pharmacogenetic biomarkers affecting drug transport, metabolism and target activity contribute to inter‐individual differences in treatment efficacy and adverse effects, supporting the implementation of personalized ...
Hossain I, Haidar M, Ratul M, Sumona J, Shabnaz S, Nokib A, Fatema‐Tuz‐Zohora.   +6 more
europepmc   +2 more sources