Results 1 to 10 of about 197,247 (118)
Chicken serum uric acid level is regulated by glucose transporter 9 [PDF]
Objective Glucose transporter 9 (GLUT9) is a uric acid transporter that is associated with uric absorption in mice and humans; but it is unknown whether GLUT9 involves in chicken uric acid regulation.
Xuedong Ding +9 more
doaj +2 more sources
Glucose Transporter 9 (GLUT9) Plays an Important Role in the Placental Uric Acid Transport System [PDF]
Background: Hyperuricemia is a common laboratory finding in pregnant women compromised by preeclampsia. A growing body of evidence suggests that uric acid is involved in the pathogenesis of preeclampsia.
Benjamin P. Lüscher +4 more
doaj +2 more sources
This work aimed to investigate the effect of fucoidan (FPS) on urate transporters induced by uric acid (UA). The results showed that UA stimulated the expression of glucose transporter 9 (GLUT9) and urate transporter 1 (URAT1) in HK-2 cells, and FPS ...
Yu Zhang +8 more
doaj +1 more source
Hyperuricemia during Pregnancy Leads to a Preeclampsia-Like Phenotype in Mice
Hyperuricemia is a common feature in pregnancies compromised by pre-eclampsia, a pregnancy disease characterized by hypertension and proteinuria. The role of uric acid in the pathogenesis of pre-eclampsia remains largely unclear.
Benjamin P. Lüscher +3 more
doaj +1 more source
Targeting tumour metabolism through glucose transporters is an attractive approach. However, the role these transporters play through interaction with other signalling proteins is not yet defined. The glucose transporter SLC2A3 (GLUT3) is a member of the
Reem Ali +9 more
doaj +1 more source
PPAR-γ regulates the effector function of human T helper 9 cells by promoting glycolysis
T helper 9 (TH9) cells promote allergic tissue inflammation and express the type 2 cytokines, IL-9 and IL-13, as well as the transcription factor, PPAR-γ. However, the functional role of PPAR-γ in human TH9 cells remains unknown.
Nicole L. Bertschi +19 more
doaj +1 more source
Context Lycium barbarum L. (Solanaceae) polysaccharides (LBPs) are important active constituents that have demonstrated kidney protection. Objective This study investigated the effect of LBPs on hyperuricaemia and explored the underlying mechanism in ...
Xin Yu +5 more
doaj +1 more source
THERAPEUTIC PHARMACOLOGICAL PROPERTIES OF CITRULLUS COLOCYNTHIS FRUIT PULPS METHANOLIC CRUDE EXTRACT AGAINST POTASSIUM OXONATE-INDUCED HYPERURICEMIC GOUT RAT MODEL [PDF]
This study was carried out to study the anti-hyperuricemic and antioxidant properties of C. colocynthis fruit pulps methanolic crude extract. The intra-peritoneal injection with 250 mg/kg/day potassium oxonate (PO) was used to develop hyperuricemic gout ...
Hosny Hassan +4 more
doaj +1 more source
Ontogenic Changes of Villus Growth, Lactase Activity, and Intestinal Glucose Transporters in Preterm and Term Born Calves with or without Prolonged Colostrum Feeding. [PDF]
Oral glucose supply is important for neonatal calves to stabilize postnatal plasma glucose concentration. The objective of this study was to investigate ontogenic development of small intestinal growth, lactase activity, and glucose transporter in calves
Julia Steinhoff-Wagner +5 more
doaj +1 more source
The present study aimed to determine the effects of polysaccharides-riched Prunus mume fruit juice concentrate (PFC) on uric acid (UA) excretion and the gut microbiota in mice with chronic kidney disease (CKD).
Yan Huang +4 more
doaj +1 more source

