Pharmaceutical Biology, 2019 Context: Eucommia ulmoides Oliver (Eucommiaceae) has various medicinal properties. Our previous studies revealed that Eucommia ulmoides has a protective effect on hyperuricaemia.
Cong Fang +8 more
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Hypouricemic Effects of Ganoderma applanatum in Hyperuricemia Mice through OAT1 and GLUT9
Frontiers in Pharmacology, 2018 Ganoderma applanatum (G. applanatum) dispels wind to eliminate dampness and exhibited nephron- and liver-protective effects as noted in Chinese herbal classic literature; it might also affect hyperuricemia. Therefore, we examined the hypouricemia effects
Tianqiao Yong +10 more
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Scientific Reports, 2021 The apelin receptor (Aplnr) and its ligands, Apelin and Apela, contribute to metabolic control. The insulin resistance associated with pregnancy is accommodated by an expansion of pancreatic β-cell mass (BCM) and increased insulin secretion, involving ...
Brenda Strutt +6 more
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The embryonic blood-CSF barrier has molecular elements for specific glucose transport and for the general transport of molecules via transcellular routes. [PDF]
, 2010 In vertebrates, early brain development takes place at the expanded anterior end of the neural tube, which is filled with embryonic cerebrospinal fluid (E-CSF).
Bueno i Torrens, David, 1965- +3 more
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Xanthene derivatives increase glucose utilization through activation of LKB1-dependent AMP-activated protein kinase. [PDF]
PLoS ONE, 2014 5' AMP-activated protein kinase (AMPK) is a highly conserved serine-threonine kinase that regulates energy expenditure by activating catabolic metabolism and suppressing anabolic pathways to increase cellular energy levels.
Yonghoon Kwon +11 more
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Sodium-glucose co-transporter 2 (SGLT2) inhibitors: a growing class of anti-diabetic agents [PDF]
, 2014 Although several treatment options are available to reduce hyperglycemia, only about half of individuals with diagnosed diabetes mellitus (DM) achieve recommended glycemic targets.
Eva M Vivian
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The sugar transporter ZmSUGCAR1 of the Nitrate Transporter 1/Peptide Transporter family is critical for maize grain filling. [PDF]
, 2022 Maternal-to-filial nutrition transfer is central to grain development and yield. Nitrate Transporter 1/Peptide Transporter (NRT1-PTR)-type transporters typically transport nitrate, peptides and ions.
Yu, Miao +22 more
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Functional characterization of a highly specific l-arabinose transporter from Trichoderma reesei
Microbial Cell Factories, 2021 Background Lignocellulose biomass has been investigated as a feedstock for second generation biofuels and other value-added products. Some of the processes for biofuel production utilize cellulases and hemicellulases to convert the lignocellulosic ...
Sami Havukainen +4 more
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Structural basis of urate transport by glucose transporter 9
Cell ReportsSummary: Glucose transporter 9 (GLUT9) is a critical urate transporter involved in renal reabsorption, playing a pivotal role in regulating physiological urate levels and representing a potential therapeutic target for gout.
Daiki Matsushita +6 more
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The sodium-dependent D-glucose transport protein of Helicobacter pylori [PDF]
, 2008 Helicobacter pylori is a gram-negative pathogenic microaerophile with a particular tropism for the mucosal surface of the gastric epithelium. Despite its obligatory microaerophilic character, it can metabolize D-glucose and/or D-galactose in both ...
Kim E. Bettaney +21 more
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