Results 201 to 210 of about 114,454,660 (263)

Oleanolic Acid‐Enriched Olive Oil Attenuates Kidney Function Decline in Patients With Type 2 Diabetes: Results From the OLTRAD Randomised Controlled Trial

Diabetes, Obesity and Metabolism, Volume 28, Issue 11, Page 10195-10209, November 2026.
ABSTRACT Aims Chronic kidney disease (CKD) is a major complication of type 2 diabetes mellitus (T2DM), driven in part by oxidative stress and the accumulation of advanced glycation end products (AGEs). Oleanolic acid (OA), a natural triterpene present in olive‐derived matrices, may modulate AGE metabolism.
Aída García‐González, Alejandro Matamoros‐Domínguez, Juan Manuel Espinosa‐Cabello, Gisela Pérez‐Muñoz, Manuel Jesús León Aranda, María Del Carmen Roque‐Cuellar, Silvia García‐Rey, Andrés Jiménez‐Sánchez, Antonio Jesús Martínez‐Ortega, Miguel Ángel Mangas‐Cruz, Isabel Cerrillo, Javier S. Perona, Pedro Pablo García‐Luna, Elena María Yubero‐Serrano, José María Castellano   +14 more
wiley   +1 more source

Gut microbiota: a novel key player in urinary stone formation - from oxalate metabolism to systemic regulation. [PDF]

Gut Microbes
Wang K, Fan W, Tang Q, Su Q.
europepmc   +1 more source

Novel Amino Acid Changes Increase Phosphoenolpyruvate Carboxylase Output in planta

Plant, Cell &Environment, Volume 49, Issue 11, Page 8306-8321, November 2026.
ABSTRACT Characterization of previously reported Arabidopsis mutants with increased aluminum (Al) resistance (alr) resulting from greater release of Al‐chelating malate identified three unique amino acid substitutions that each impacts PHOSPHOENOLPYRUVATE CARBOXYLASE 1, a key anaplerotic carbon fixation enzyme.
Jinrui Sheng, Kevin Frausto, Sarah Haesaerts, Taylor J. Meyer, Maruša Prolič‐Kalinšek, Seán E. O'Leary, Remy Loris, Paul B. Larsen   +7 more
wiley   +1 more source

Multi-omics insights into uric acid metabolism in cardiometabolic disease: from genetics to metabolomics. [PDF]

Biomed J
Ali N.
europepmc   +1 more source

Hirudin Attenuates Uric Acid-Induced Renal Tubular Injury via TNFRSF6B-Mediated Suppression of NF-κB Signaling. [PDF]

Pharmacol Res Perspect
Zhao Y, Qin Y, He L, Luo H, Mo Y, Zhou W, He H, Zhou G, Liu X.   +8 more
europepmc   +1 more source

Association of Neutrophil Percentage‐to‐Albumin Ratio (NPAR) With Pathological Features and Long‐Term Prognosis in Diabetic Kidney Disease: A Cohort Study

The FASEB Journal, Volume 40, Issue 19, 15 October 2026.
This graphical abstract summarizes the association between the neutrophil percentage‐to‐albumin ratio (NPAR), renal pathology, and prognosis in biopsy‐confirmed diabetic kidney disease. Higher NPAR was associated with increased renal MPO‐positive neutrophil infiltration, more severe histopathological injury, and poorer renal outcomes.
Yang Li, Hongyu Wang, Wendi He, Yi Fang, Shi Jin, Hong Liu, Jie Li, Nana Song, Xiaoqiang Ding, Yan Dai   +9 more
wiley   +1 more source

Uric Acid and Chronic Kidney Disease. [PDF]

Kidney Med
Yadlapalli S, Nekkalapudi DK, Wish JB.
europepmc   +1 more source

One Hundred Years of Sulfido Ligand in the Molybdenum Cofactor: New Perspectives

ChemBioChem, Volume 27, Issue 19, 14 October 2026.
The terminal sulfido ligand in mononuclear molybdoenzymes has been appreciated for almost 125 years, with the characterization of Schardinger's enzyme in cow's milk, now known to be xanthine oxidase, that was isolated in 1902 in Vienna, Austria. The ligand is found in molybdoenzymes identified across all kingdoms of life.
Silke Leimkühler, Benjamin R. Duffus, Carola Schulzke   +2 more
wiley   +1 more source

SGLT2 Inhibitors in Nephrolithiasis: Emerging Evidence and What Urologists Need to Know. [PDF]

Med Sci (Basel)
Ivănuță M, Puia D, Ivănuță AM, Haută A, Nistor I, Pricop C.   +5 more
europepmc   +1 more source

Epigenetic Mechanism of Heart Failure with Preserved Ejection Fraction (HFpEF). [PDF]

J Cardiovasc Dev Dis
Tyagi SC, Ovechkin AV.
europepmc   +1 more source