Glucokinase Variant Proteins Are Resistant to Fasting-Induced Uridine Diphosphate Glucose-Dependent Degradation in Maturity-Onset Diabetes of the Young Type 2 Patients. [PDF]
Int J Mol Sci, 2023 Cho J +5 more
europepmc +1 more source
ChemBioChem, Volume 26, Issue 11, June 3, 2025.In the nascent processes of the beginnings and evolution of life, nucleobases and especially purines, ribonucleos(t)ides and primitive RNAs have been continuously modified. A RNA‐peptide world and key metabolic pathways probably have emerged from the corresponding chemical modifications resulting from adenine deamination, purine alkylation and ...
Jean‐Luc Décout +1 more
wiley +1 more source
ATP binding cassette transporters and uridine diphosphate glycosyltransferases are ancient protein families that evolved roles in herbicide resistance through exaptation. [PDF]
PLoS One, 2023 Caygill S, Dolan L.
europepmc +1 more source
Identification of Genetic Variants Associated with Pravastatin and Pitavastatin Pharmacokinetics
Clinical Pharmacology &Therapeutics, Volume 117, Issue 6, Page 1763-1774, June 2025.A clinical trial was carried out to investigate the pharmacogenetics of single‐dose pravastatin and pitavastatin pharmacokinetics in 173 and 164 healthy participants. Additionally, 96 participants were included from previous pharmacogenetic studies with pravastatin. In a genome‐wide meta‐analysis of pravastatin including all 269 participants, SLCO1B1 c.
Anssi J. H. Mykkänen +9 more
wiley +1 more source
Uridine Diphosphate Glycosyltransferases (UGTs) Involved in the Carotenoid-Based Body Color Difference between Tetranychus cinnabarinus (Red) and Tetranychus urticae (Green). [PDF]
Insects, 2023 Xu Z +7 more
europepmc +1 more source
Beyond Conventional Approaches: The Revolutionary Role of Nanoparticles in Breast Cancer
MedComm – Biomaterials and Applications, Volume 4, Issue 2, June 2025.This review explores integrated approach of nanotechnology to breast cancer diagnosis and treatment. We highlight imaging techniques for tumor detection and biomarker analysis in biological samples for early diagnosis. Advanced therapies, including targeted drug delivery and antibody‐drug conjugates, enable precise medication transport to cancer cells,
Mohan Liu +7 more
wiley +1 more source
The Uridine diphosphate (UDP)-glycosyltransferases (UGTs) superfamily: the role in tumor cell metabolism. [PDF]
Front Oncol, 2022 Liu W, Li J, Zhao R, Lu Y, Huang P.
europepmc +1 more source
Functional 31P Magnetic Resonance Spectroscopy at 9.4 T
NMR in Biomedicine, Volume 38, Issue 6, June 2025.Functional 31P MRS in healthy subjects at 9.4 T was applied to investigate changes in the energy metabolism of the brain during visual stimulation. Stimulation and rest spectra from the visual cortex only differed in a small but highly significant shift in the chemical shift of anorganic phosphate.
Rolf Pohmann +2 more
wiley +1 more source
5'-nucleotidases, nucleosides and their distribution in the brain: pathological and therapeutic implications [PDF]
, 2013 Elements of the nucleoside system (nucleoside levels, 5'-nucleotidases (5'NTs) and other nucleoside metabolic enzymes, nucleoside transporters and nucleoside receptors) are unevenly distributed in the brain, suggesting that nucleosides have region ...
Dobolyi, Árpád +3 more
core
Biosynthesis of uridine diphosphate N-Acetylglucosamine: An underexploited pathway in the search for novel antibiotics? [PDF]
IUBMB Life, 2022 Wyllie JA +3 more
europepmc +1 more source