Microbial exopolysaccharide production by polyextremophiles in the adaptation to multiple extremes
FEBS Letters, Volume 599, Issue 23, Page 3417-3443, December 2025.Polyextremophiles are microorganisms that endure multiple extreme conditions by various adaptation strategies that also include the production of exopolysaccharides (EPSs). This review provides an integrated perspective on EPS biosynthesis, function, and regulation in these organisms, emphasizing their critical role in survival and highlighting their ...
Tracey M Gloster, Ebru Toksoy Öner
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The Concise Guide to PHARMACOLOGY 2025/26: Transporters
British Journal of Pharmacology, Volume 182, Issue S1, Page S404-S496, December 2025.The Concise Guide to Pharmacology 2025/26 marks the seventh edition in this series of biennial publications in the British Journal of Pharmacology. Presented in landscape format, the guide provides a comparative overview of the pharmacology of drug target families. The concise nature of the Concise Guide refers to the style of presentation, being clear,
Stephen P. H. Alexander +28 more
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ChemSusChem, Volume 18, Issue 20, October 23, 2025.Developing a process to produce glycosylated natural products involves many decisions, and given the current climate crisis, the environmental impact of the various processes must be a major consideration. This review provides an overview of the various processes and a framework for which metrics should be quantified to select processes that are both ...
Felipe Mejia‐Otalvaro +3 more
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Macrophage Efferocytosis as a Therapeutic Strategy in Intervertebral Disc Degeneration
Cell Proliferation, Volume 58, Issue 10, October 2025.Macrophages, integral to degenerated intervertebral discs, play a critical role in disc degeneration. By performing efferocytosis, they clear apoptotic cells. This article explores the process of efferocytosis, its molecular mechanisms, potential therapeutic implications for intervertebral disc degeneration and future strategies for targeted treatments.
Shijie Chen +9 more
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Unveiling the catalytical roles of three glycosyltransferases in triterpenoid saponins in quinoa
Plant Biotechnology Journal, Volume 23, Issue 10, Page 4214-4227, October 2025.Summary Saponins constitute a class of characteristic compounds within quinoa grains. In this study, metabolomic analysis identified 20 triterpene saponins, the majority of which were exclusively localized within the pericarp. Furthermore, three crucial glycosyltransferases were identified in quinoa.
Yiming Zhang +14 more
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Beyond FimH: Diversity and Relevance of Carbohydrate‐Binding Fimbrial Proteins in Escherichia coli
ChemBioChem, Volume 26, Issue 17, September 15, 2025.This review discusses fimbrial lectins found in Escherichia coli (E. coli) other than FimH, which could be targeted to treat E. coli pathogenicity as an alternative to antibiotic treatment. Escherichia coli (E. coli) is responsible for multiple diseases in humans and animals.
Oliwier R. Dulawa +3 more
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Bleeding, Thrombosis and Vascular BiologyBackground and Aims: Evaluation of platelet morphology is a cornerstone of the diagnostic work-up of patients with suspected inherited platelet disorders (IPD).
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Galactosaemia: a new severe variant due to uridine diphosphate galactose-4-epimerase deficiency. [PDF]
, 1981 J. B. Holton +3 more
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Studies on the thiol group of lactose synthetase A protein from human milk and on the binding of uridine diphosphate galactose to the enzyme [PDF]
, 1974 Barry J. Kitchen, P Andrews
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Bacteriophage Receptor Development and Synthesis of O-Specific Side Chains After Addition of
, 1970 Alf A. Lindberg +3 more
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