Results 51 to 60 of about 4,041 (175)

The human UDP-galactose 4'-epimerase (GALE) is required for cell-surface glycome structure and function.

open access: yes, 2020
Glycan biosynthesis relies on nucleotidesugars (NS), abundant metabolites that serve as monosaccharide donors for glycosyltransferases. In vivo, signal-dependent fluctuations in NS levels are required to maintain normal cell physiology and are ...
Desbiens, Chelsea   +8 more
core   +1 more source

Chondroitin Sulfate Proteoglycans in CNS Development and Pathophysiology

open access: yesJournal of Neuroscience Research, Volume 104, Issue 3, March 2026.
Chondroitin sulfate proteoglycans (CSPGs) are critical components of the extracellular matrix in the central nervous system (CNS). In the developing CNS, CSPGs regulate neural precursor cells, neuronal migration, axon guidance, synapse organization, and peri‐neuronal net assembly.
Seyed Mojtaba Hosseini   +1 more
wiley   +1 more source

Effect of galactose and glucose on the exopolysaccharide production and the activities of biosynthetic enzymes in Lactobacillus casei CRL 87 [PDF]

open access: yes, 2001
Aims: The objective of this work was to study the influence of the sugar source on exopolysaccharide (EPS) production and the activities of the enzymes involved in the synthesis of sugar nucleotides in Lactobacillus casei CRL 87. The relationship between
Font, Graciela Maria   +3 more
core   +1 more source

Metabolic Dynamics of Central Carbon Pathways in Green‐Lipped Mussels under Heat Stress and Subsequent Recovery

open access: yesNew Zealand Journal of Marine and Freshwater Research, Volume 60, Issue 1, March 2026.
Green‐lipped mussel (Perna canaliculus) aquaculture is vulnerable to environmental changes, which are increasingly being studied to pinpoint physiological, economic and ecological threats. This study utilised a targeted liquid chromatography‐mass spectrometry metabolomics approach, focusing on the central carbon metabolism, to examine the metabolic ...
Leonie Venter   +6 more
wiley   +1 more source

Mild Short‐Term Caloric Restriction Induces Coordinated Changes That Promote Lipid Deposition While Maintaining Thermogenesis Capacity in Interscapular Brown Adipose Tissue of Male Rats

open access: yesThe FASEB Journal, Volume 40, Issue 3, 15 February 2026.
Rats under mild caloric restriction (85% vs. ad libitum) for 2 weeks show metabolic and structural adaptations in iBAT. Caloric restriction increases glycolysis and triglyceride deposition in the tissue, leading to larger lipid droplets. It also reduces mitochondrial iBAT content, while maintaining iBAT thermogenic potential thanks to an increased ...
Giuliana Panico   +11 more
wiley   +1 more source

Enhancing Glycosylation of Flavonoids by Engineering the Uridine Diphosphate Glucose Supply in Escherichia coli

open access: yes
Glycosylation can enhance the solubility and stability of flavonoids. The main limitation of the glycosylation process is low intracellular uridine diphosphate glucose (UDPG) availability.
Jingwen Zhou (591817)   +4 more
core   +1 more source

Induced Reoxidation and Reactivation of a Reduced Uridine Diphosphate Galactose-4-epimerase Complex

open access: yesJournal of Biological Chemistry, 1974
Abstract An inactive reduced UDP-galactose-4-epimerase complex, which is prepared by reduction with NaBH4 in the presence of substrates and is known to contain DPNH and UDP-hexoses in tightly bound form, is largely reoxidized and partially reactivated in the presence of 0.02 to 0.4 m cyclohexanone or cyclohexanol.
T G, Wee, P A, Frey
openaire   +2 more sources

Distinct Metabolomic Alterations Are Associated With Physical Function, Weight Loss, and Muscle Mass in Men With Cancer

open access: yesJournal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 1, February 2026.
ABSTRACT Background Treatments for cancer cachexia, defined as involuntary weight and muscle mass loss leading to significant functional impairment, remain unavailable partly due to insufficient improvement of clinically meaningful outcomes in current trials.
Lindsey J. Anderson   +9 more
wiley   +1 more source

In situ localization of galactosyltransferase in surface mucous cells of the rat stomach.

open access: yes, 1977
Cryostate sections of the rat stomach fundus were incubated in the presence of uridine 5'-diphosphate-[3H]-galactose. The radioactivity in the surface mucous epithelial cells was shown by autoradiography to be specifically incorporated into a ...
C Poort
core   +1 more source

Biological examples of qORAC.

open access: yes, 2018
Four well-characterised metabolic pathways in which a metabolite binds to a transcription factor (TF) to influence gene expression. The qORAC framework applies to each of them: in each case, the qORAC formalism gives rise to the enzyme synthesis rates ...
Josephus Hulshof (5774216)   +4 more
core   +1 more source

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