Genome-wide analysis of the UDP-glucose dehydrogenase gene family in Arabidopsis, a key enzyme for matrix polysaccharides in cell walls [PDF]
, 2007 Arabidopsis cell walls contain large amounts of pectins and hemicelluloses, which are predominantly synthesized via the common precursor UDP-glucuronic acid.
Klinghammer, Michaela, Tenhaken, Raimund
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Enzymatic studies of glucuronide formation in impaired liver. II. Activating effect of boiled liver extract on liver glucuronide formation [PDF]
, 1962 The effect of the boiled liver extract on the velocity of 4-methyl umbelliferone lucuronide formation by mouse liver homogenate was studied. The results were as follows: 1.
Taketa, Kazuhisa
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Metabolic Control of Cardiomyocyte Cell Cycle
Methodist DeBakey Cardiovascular Journal, 2023 Current therapies for heart failure aim to prevent the deleterious remodeling that occurs after MI injury, but currently no therapies are available to replace lost cardiomyocytes.
Ivan Menendez-Montes +3 more
doaj +1 more source
Metabolic processes sustaining the reviviscence of lichen Xanthoria elegans (Link) in high mountain environments. [PDF]
, 2007 International audienceTo survive in high mountain environments lichens must adapt themselves to alternating periods of desiccation and hydration. Respiration and photosynthesis of the foliaceous lichen, Xanthoria elegans, in the dehydrated state were ...
Aubert, Serge +4 more
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UPLC-QE-MS Analysis of the Differences in Milk Metabolites from Guanzhong Dairy Goats at the Peak and Late Lactation Stages [PDF]
Shipin KexueIn order to explore the dynamic changes of metabolites in goat milk during different lactation periods, the differential metabolites in milk from Guanzhong dairy goats at the peak and late lactation stages were investigated by ultra-high performance ...
YU Mengqi, YUAN Yuxin, CHEN Lu, SHARI Akang, REN Xinyang, QU Yingxin, LI Guang
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Antitoxin ε Reverses Toxin ζ-Facilitated Ampicillin Dormants
Toxins, 2020 Toxin-antitoxin (TA) modules are ubiquitous in bacteria, but their biological importance in stress adaptation remains a matter of debate. The inactive ζ-ε2-ζ TA complex is composed of one labile ε2 antitoxin dimer flanked by two stable ζ toxin monomers ...
María Moreno-del Álamo +2 more
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Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Nationwide patient registry for GNE myopathy in Japan [PDF]
, 2014 BACKGROUND: GNE myopathy is a slowly progressive autosomal recessive myopathy caused by mutations in the GNE (glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase) gene.
En Kimura +7 more
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A Synergistic Inhibitor Development Strategy Against Human UDP‐Galactose‐4‐Epimerase
Angewandte Chemie International Edition, EarlyView.The epimerase GalE is crucial for the biosynthesis of cancer‐relevant O‐GalNAc glycans. Here, we employ orthogonal, structurally enabled small molecule fragment screens to yield both covalent and non‐covalent inhibitors against GalE within no more than 22 elaborated compounds.
William M. Browne +22 more
wiley +1 more source
Effects of exercise on the hexosamine biosynthetic pathway and glycosylation
Journal of Physical Fitness and Sports Medicine, 2012 Minor amounts of glucose incorporated into the cells is metabolized via the hexosamine biosynthetic pathway, resulting in the production of uridine-5’-diphosphate-N-acetylglucosamine (UDP-GlcNAc), which is utilized as a donor substrate for the N- and O ...
Ken Shirato +3 more
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