Results 61 to 70 of about 7,626 (203)

An Untargeted Metabolomics Approach to Study the Variation between Wild and Cultivated Soybeans

open access: yesMolecules, 2023
The differential metabolite profiles of four wild and ten cultivated soybeans genotypes were explored using an untargeted metabolomics approach. Ground soybean seed samples were extracted with methanol and water, and metabolic features were obtained ...
Fakir Shahidullah Tareq   +4 more
doaj   +1 more source

Regulatory role of hexosamine biosynthetic pathway on hepatic cancer stem cell marker CD133 under low glucose conditions [PDF]

open access: yes, 2016
published_or_final_versio
Cai, Z   +8 more
core   +1 more source

Determinants of Phage Host Range in Staphylococcus Species. [PDF]

open access: yes, 2019
Bacteria in the genus Staphylococcus are important targets for phage therapy due to their prevalence as pathogens and increasing antibiotic resistance.
Lindsay, JA, Moller, AG, Read, TD
core   +1 more source

Fibroblasts from patients with I-cell disease and pseudo-Hurler polydystrophy are deficient in uridine 5'-diphosphate-N-acetylglucosamine: glycoprotein N-acetylglucosaminylphosphotransferase activity. [PDF]

open access: yesJournal of Clinical Investigation, 1981
Newly synthesized acid hydrolases, destined for transport to lysosomes, acquire a phosphomannosyl targeting signal by the transfer of N-acetylglucosamine 1-phosphate from uridine 5'-diphosphate (UDP)-N-acetylglucosamine to a mannose residue of the acid hydrolase followed by removal of the outer, phosphodiester-linked N-acetylglucosamine to expose 6 ...
M L, Reitman, A, Varki, S, Kornfeld
openaire   +2 more sources

Selectively improving nikkomycin Z production by blocking the imidazolone biosynthetic pathway of nikkomycin X and uracil feeding in [PDF]

open access: yes, 2009
Background Nikkomycins are a group of peptidyl nucleoside antibiotics and act as potent inhibitors of chitin synthases in fungi and insects. Nikkomycin X and Z are the main components produced by Streptomyces ansochromogenes.
Yang Haihua   +5 more
core   +1 more source

Efficient chemoenzymatic synthesis of uridine 5′-diphosphate N-acetylglucosamine and uridine 5′-diphosphate N-trifluoacetyl glucosamine with three recombinant enzymes

open access: yesPreparative Biochemistry & Biotechnology, 2017
Uridine 5′-diphosphate N-acetylglucosamine (UDP-GlcNAc) is a natural UDP-monosaccharide donor for bacterial glycosyltransferases, while Uridine 5′-diphosphate N-trifluoacetyl glucosamine (UDP-GlcNTFA) is its synthetic mimic. The chemoenzymatic synthesis of UDP-GlcNAc and UDP-GlcNTFA was attempted by three recombinant enzymes.
Xiaoyan, Li   +5 more
openaire   +2 more sources

Genetic basis for hyper production of hyaluronic acid in natural and engineered microorganisms [PDF]

open access: yes, 2016
Hyaluronic acid, or HA, is a rigid and linear biopolymer belonging to the class of the glycosaminoglycans, and composed of repeating units of the monosaccharides glucuronic acid and N-acetylglucosamine.
Carvalho, Lucas Silva   +5 more
core   +2 more sources

In Silico Screening and Analysis of Broad-Spectrum Molecular Targets and Lead Compounds for Diarrhea Therapy

open access: yesBioinformatics and Biology Insights, 2019
Diarrhoeal disease kills about 1.5 million human beings per year across the continents. The enterotoxigenic Escherichia coli (ETEC) pathotype has been noted as a major cause of diarrheal disease in human and livestock.
Harriet U Ugboko   +5 more
doaj   +1 more source

Systematic analyses of glutamine and glutamate metabolisms across different cancer types

open access: yesChinese Journal of Cancer, 2017
Background Glutamine and glutamate are known to play important roles in cancer biology. However, no detailed information is available in terms of their levels of involvement in various biological processes across different cancer types, whereas such ...
Yuan Tian   +6 more
doaj   +1 more source

Tisp40 prevents cardiac ischemia/reperfusion injury through the hexosamine biosynthetic pathway in male mice

open access: yesNature Communications, 2023
The hexosamine biosynthetic pathway (HBP) produces uridine diphosphate N-acetylglucosamine (UDP-GlcNAc) to facilitate O-linked GlcNAc (O-GlcNAc) protein modifications, and subsequently enhance cell survival under lethal stresses.
Xin Zhang   +9 more
doaj   +1 more source

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