Molecular Weight of Urokinase [PDF]
Nature, 1965 UROKINASE is a proteolytic enzyme in human urine1. Its ability to activate plasminogen has stimulated interest in its potential clinical use as a thrombolytic agent.
Roger A. Burges +2 more
openalex +4 more sources
Journal of Biological Chemistry, 1986 Urokinase-related proteins were purified from 60-liter batches of human urine collected into the protease inhibitor aprotinin to prevent proteolytic degradation. Three homogeneous species were obtained by chromatography on zinc chelate-Sepharose, SP-Sephadex C-50, Sephadex G-100, benzamidine-Sepharose, and immunoadsorption on a murine anti-human ...
D C Stump, M Thienpont, Désiré Collen
openalex +4 more sources
Numerical study of cancer cell invasion dynamics using adaptive mesh refinement: the urokinase model [PDF]
arXiv, 2014 In the present work we investigate the chemotactically and proteolytically driven tissue invasion by cancer cells. The model employed is a system of advection-reaction-diffusion equations that features the role of the serine protease urokinase-type plasminogen activator.
Hellmann, Nadja +4 more
arxiv +2 more sources
Safety and efficacy of tirofiban after intravenous thrombolysis with urokinase in patients with acute ischemic stroke. [PDF]
Front NeurolIntroductionTirofiban combined with alteplase thrombolysis or endovascular therapy has been proven to improve the prognosis of patients with acute ischemic stroke (AIS).
Qu D +7 more
europepmc +2 more sources
Efficacy of YL-1 hematoma crushing needle combined with hematoma drainage in intracerebral hemorrhage treatment. [PDF]
Front Med (Lausanne)ObjectiveEarly craniotomy evacuation in hematoma surgery does not significantly improve the prognosis of patients with spontaneous intracerebral hemorrhage (ICH).
Chen X +5 more
europepmc +2 more sources
Treatment with urokinase. [PDF]
British Journal of Ophthalmology, 1977 Wc H, Tavistock Square, London
openalex +4 more sources
Intravenous Thrombolysis with Urokinase for Acute Ischemic Stroke. [PDF]
Brain SciBackground: Intravenous thrombolysis is one of the most effective therapies for the treatment of acute ischemic stroke (AIS), with urokinase offering a cost-effective alternative to newer agents like alteplase and tenecteplase, especially in resource ...
Qiao Y +5 more
europepmc +2 more sources
Non-Surgical Bleeding and Transurethral Resection of the Prostate (TURP) Syndrome after TURP Surgery: A Case Report and Literature Review. [PDF]
PathophysiologyPatients undergoing transurethral resection of the prostate (TURP) surgery can develop TURP syndrome and post-TURP bleeding. Post-TURP bleeding can be surgical, from arteries or venous sinuses, or non-surgical, due to coagulopathy preventing clot ...
Eraky AM +4 more
europepmc +2 more sources
Efficacy and safety of catheter-directed thrombolytic therapy of alteplase and urokinase for the treatment of deep vein thrombosis: a Meta-analysis [PDF]
Yixue xinzhi zazhi, 2023 Objective To systematically review the effectiveness and safety of cathe-ter-directed thrombolytic therapy (CDT) using alteplase and urokinase in the treatment of deep vein thrombosis (DVT) in the lower extremities.Method PubMed, The Cochrane Library ...
Hong-Yan LI +6 more
doaj +1 more source
Fibrinolysis with Lower Dose Urokinase in Patients with Complicated Parapneumonic Effusion [PDF]
Tuberculosis and Respiratory Diseases, 2021 Background Intrapleural urokinase is one of the most widely used fibrinolytic agents in the treatment of complicated parapneumonic effusion (CPPE). However, little research has been performed on the optimal urokinase dosage.
Seul Lee +8 more
doaj +1 more source