A matters arising: discussion on urokinase dosing and individualized treatment strategies in the TRUST trial [PDF]
BMC MedicineThis matters arising addresses the recently published article in BMC Medicine by Tao Y et al., entitled “Effect of intravenous urokinase vs best medicine treatment on functional outcome for patients with acute minor stroke (TRUST): a randomized ...
Yue Qiao, Xunming Ji, Wenbo Zhao
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A case of complicated parapneumonic pleural effusion caused by paragonimus infection in a child was successfully treated by intrapleural injection of urokinase: a case report and literature review [PDF]
Frontiers in PediatricsObjectiveThe clinical data of a child with complex parapneumonic effusion (PPE) caused by pneumofluke infection were analyzed, and the diagnosis and treatment of the disease were discussed through literature review.
Yangyi Shi, Yan Li, Yu Hu
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Safety and efficacy of tirofiban after intravenous thrombolysis with urokinase in patients with acute ischemic stroke [PDF]
Frontiers in NeurologyIntroductionTirofiban combined with alteplase thrombolysis or endovascular therapy has been proven to improve the prognosis of patients with acute ischemic stroke (AIS).
Dian Qu +7 more
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Efficacy and safety of catheter-directed thrombolytic therapy of alteplase and urokinase for the treatment of deep vein thrombosis: a Meta-analysis [PDF]
Yixue xinzhi zazhi, 2023 Objective To systematically review the effectiveness and safety of cathe-ter-directed thrombolytic therapy (CDT) using alteplase and urokinase in the treatment of deep vein thrombosis (DVT) in the lower extremities.Method PubMed, The Cochrane Library ...
Hong-Yan LI +6 more
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Fibrinolysis with Lower Dose Urokinase in Patients with Complicated Parapneumonic Effusion [PDF]
Tuberculosis and Respiratory Diseases, 2021 Background Intrapleural urokinase is one of the most widely used fibrinolytic agents in the treatment of complicated parapneumonic effusion (CPPE). However, little research has been performed on the optimal urokinase dosage.
Seul Lee +8 more
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Neurologia Medico-Chirurgica, 2022 Delayed cerebral vasospasms after subarachnoid hemorrhage (SAH) are a risk factor for poor prognosis after successful treatment of ruptured intracranial aneurysms.
Arata NAGAI +5 more
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Fibrinolysis regulation by platelets retaining plasminogen and tissue-type plasminogen activator on their surface [PDF]
The Ukrainian Biochemical Journal, 2019 Platelets play a key role in hemostasis as cofactors of thrombin generation, fibrin polymerization centers, and initiators of clot retraction, while their ability to modulate clot dissolution remains less understood.
T. Grinenko +4 more
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Frontiers in Neurology, 2021 Background: Intravenous thrombolysis with alteplase benefits eligible patients with acute ischemic stroke. However, in some countries such as China, alteplase may be too expensive for low-income patients, and also for regions with low economic ...
Rongrong Zhang +11 more
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Frontiers in Neurology, 2021 Background: Current clinical guidelines recommend systemic anticoagulation as the initial treatment for severe cerebral venous sinus thrombosis (CVST).
Jiansheng Yang +5 more
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Sequential intrapleural administration of fibrinolytic drugs and dornase alfa for empyema management. Treatment protocol based on its physicochemical stability [PDF]
Farmacia Hospitalaria, 2020 Objective: Intrapleural administration of fibrinolytics and dornase alfa has been shown in randomized studies to be able to reduce both the need for surgical debridement of empyema and the average hospital stay.
Carla Bastida +5 more
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