Results 91 to 100 of about 78,313 (276)

Activation of the Urokinase Plasminogen Activator/Urokinase Plasminogen Activator Receptor System in Periodontitis: A Case–Control Study

open access: yesInternational Journal of Dental Hygiene, EarlyView.
ABSTRACT Introduction The plasminogen activating (PA) system has a multitude of functions such as wound healing, proteolytic activity, collagen degradation and cell growth, and the role of the urokinase plasminogen activator/urokinase plasminogen activator receptor (uPA/uPAR) system has been studied in many disease states.
Ahmed Khudhur   +6 more
wiley   +1 more source

Urokinase gene 3'-UTR T/C polymorphism is not associated with bladder cancer

open access: yesGenetics and Molecular Biology, 2004
Urokinase degrades basement proteins and is hypothesized to play a role in cancer progression. We investigated the hypothesis of C/T polymorphism in the 3'-untranslated region (3'-UTR) of the urokinase gene being associated with the development of ...
Wu Hsi-Chin   +4 more
doaj   +1 more source

Effects of natto extract on endothelial injury in a rat model [PDF]

open access: yes, 2010
Vascular endothelial damage has been found to be associated with thrombus formation, which is considered to be a risk factor for cardiovascular disease. A diet of natto leads to a low prevalence of cardiovascular disease. The aim of the present study was
Chang, Chin-Hsien   +8 more
core   +1 more source

Distinct ligand binding sites in integrin alpha3beta1 regulate matrix adhesion and cell-cell contact. [PDF]

open access: yes, 2003
The integrin alpha3beta1 mediates cellular adhesion to the matrix ligand laminin-5. A second integrin ligand, the urokinase receptor (uPAR), associates with alpha3beta1 via a surface loop within the alpha3 beta-propeller (residues 242-246) but outside ...
Chapman, Harold A   +6 more
core  

Selection Of A Novel Aptamer Against Vitronectin Using Capillary Electrophoresis And Next Generation Sequencing [PDF]

open access: yes, 2016
Breast cancer (BC) results in ≃40,000 deaths each year in the United States and even among survivors treatment of the disease may have devastating consequences, including increased risk for heart disease and cognitive impairment resulting from the toxic ...
Boyacioglu, O.   +8 more
core   +3 more sources

Excessive hypercholesterolaemia during pregnancy as a risk factor for endothelial dysfunction in pre‐eclampsia

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Excessive hypercholesterolaemia during pregnancy impairs maternal endothelial function, which, in turn, drives the development of pre‐eclampsia and may also contribute to the increased risk of later‐life cardiovascular disease in women.
Amanda A. de Oliveira   +3 more
wiley   +1 more source

Comparación de la activación y la cinética de la plasmina bufalina con la humana Ativação e cinética comparativa da plasmina bufalina e a humana Comparative activation and kinetic of plasmin bufaline with the human one

open access: yesRevista Colombiana de Ciencias Pecuarias, 2010
El plasminógeno es el zimógeno de la plasmina, enzima activada a nivel fisiológico por el activador tisular del plasminógeno y la urokinasa, la plasmina es la enzima encargada de disolver el coágulo sanguíneo.
Omaira Cañas Bermúdez   +2 more
doaj  

Induction of Urokinase Activity by Retinoic Acid in Two Cell Lines of Neuronal Origin

open access: yesBiomedicines, 2019
Retinoic acid is one of the most well-known agents able to induce differentiation in several types of tumours. Unfortunately, most of the tumours are refractive to the differentiation cues.
Luka Horvat   +4 more
doaj   +1 more source

Obesity Biomarkers: Exploring Factors, Ramification, Machine Learning, and AI‐Unveiling Insights in Health Research

open access: yesMedComm, Volume 6, Issue 7, July 2025.
The graphical abstract emphasizes the complex nature of obesity, focusing on the interaction of behavioral, sociodemographic, genetic, and biomarker factors. It illustrates how lifestyle habits, demographics, and genetic predispositions influence obesity risk.
Ankita Awari   +8 more
wiley   +1 more source

Fibrinolysis protease receptors promote activation of astrocytes to express pro-inflammatory cytokines. [PDF]

open access: yes, 2019
BACKGROUND:Astrocytes contribute to the crosstalk that generates chronic neuro-inflammation in neurological diseases; however, compared with microglia, astrocytes respond to a more limited continuum of innate immune system stimulants.
Azmoon, Pardis   +8 more
core   +1 more source

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