Results 91 to 100 of about 78,313 (276)
ABSTRACT Introduction The plasminogen activating (PA) system has a multitude of functions such as wound healing, proteolytic activity, collagen degradation and cell growth, and the role of the urokinase plasminogen activator/urokinase plasminogen activator receptor (uPA/uPAR) system has been studied in many disease states.
Ahmed Khudhur+6 more
wiley +1 more source
Urokinase gene 3'-UTR T/C polymorphism is not associated with bladder cancer
Urokinase degrades basement proteins and is hypothesized to play a role in cancer progression. We investigated the hypothesis of C/T polymorphism in the 3'-untranslated region (3'-UTR) of the urokinase gene being associated with the development of ...
Wu Hsi-Chin+4 more
doaj +1 more source
Effects of natto extract on endothelial injury in a rat model [PDF]
Vascular endothelial damage has been found to be associated with thrombus formation, which is considered to be a risk factor for cardiovascular disease. A diet of natto leads to a low prevalence of cardiovascular disease. The aim of the present study was
Chang, Chin-Hsien+8 more
core +1 more source
Distinct ligand binding sites in integrin alpha3beta1 regulate matrix adhesion and cell-cell contact. [PDF]
The integrin alpha3beta1 mediates cellular adhesion to the matrix ligand laminin-5. A second integrin ligand, the urokinase receptor (uPAR), associates with alpha3beta1 via a surface loop within the alpha3 beta-propeller (residues 242-246) but outside ...
Chapman, Harold A+6 more
core
Selection Of A Novel Aptamer Against Vitronectin Using Capillary Electrophoresis And Next Generation Sequencing [PDF]
Breast cancer (BC) results in ≃40,000 deaths each year in the United States and even among survivors treatment of the disease may have devastating consequences, including increased risk for heart disease and cognitive impairment resulting from the toxic ...
Boyacioglu, O.+8 more
core +3 more sources
Abstract figure legend Excessive hypercholesterolaemia during pregnancy impairs maternal endothelial function, which, in turn, drives the development of pre‐eclampsia and may also contribute to the increased risk of later‐life cardiovascular disease in women.
Amanda A. de Oliveira+3 more
wiley +1 more source
El plasminógeno es el zimógeno de la plasmina, enzima activada a nivel fisiológico por el activador tisular del plasminógeno y la urokinasa, la plasmina es la enzima encargada de disolver el coágulo sanguíneo.
Omaira Cañas Bermúdez+2 more
doaj
Induction of Urokinase Activity by Retinoic Acid in Two Cell Lines of Neuronal Origin
Retinoic acid is one of the most well-known agents able to induce differentiation in several types of tumours. Unfortunately, most of the tumours are refractive to the differentiation cues.
Luka Horvat+4 more
doaj +1 more source
The graphical abstract emphasizes the complex nature of obesity, focusing on the interaction of behavioral, sociodemographic, genetic, and biomarker factors. It illustrates how lifestyle habits, demographics, and genetic predispositions influence obesity risk.
Ankita Awari+8 more
wiley +1 more source
Fibrinolysis protease receptors promote activation of astrocytes to express pro-inflammatory cytokines. [PDF]
BACKGROUND:Astrocytes contribute to the crosstalk that generates chronic neuro-inflammation in neurological diseases; however, compared with microglia, astrocytes respond to a more limited continuum of innate immune system stimulants.
Azmoon, Pardis+8 more
core +1 more source