Results 101 to 110 of about 43,123 (212)

Bone Metastasis: Molecular Mechanisms, Clinical Management, and Therapeutic Targets

MedComm, Volume 7, Issue 2, February 2026.
This figure emphasizes current understanding of the regulatory networks, approach of diagnose, available preclinical models and clinical management of bone metastasis. to guide future therapeutic development. A deep understanding of these aspects enables the prevention of bone metastasis and the implementation of effective therapeutic strategies ...
Jingyuan Wen, Binghua Li, Shengjia Wang, Yongzhong Yao, Zhao Huang, Decai Yu   +5 more
wiley   +1 more source

Plasma Soluble Urokinase-Type Plasminogen Activator Receptor Is Not Associated with Neurological Outcome in Patients with Aneurysmal Subarachnoid Hemorrhage [PDF]

, 2017
Heikki Kiiski, Ville Jalkanen, Marika Ala-Peijari, Mari Hämäläinen, Eeva Moilanen, Jukka Peltola, Jyrki Tenhunen   +6 more
openalex   +1 more source

Isoquercetin and Zafirlukast Cooperatively Suppress Tumor Growth and Thromboinflammatory Signaling in a Xenograft Model of Ovarian Cancer

The FASEB Journal, Volume 40, Issue 1, 15 January 2026.
Treatment using either the thiol isomerase inhibitor isoquercetin or zafirlukast lowers tissue factor levels, decreases VEGF, inhibits PD‐L1, and TMEM176B in a xenograft model of ovarian cancer. A combination of the two agents, at threefold lower concentrations than either drug, significantly enhanced the inhibition further, suggesting a dual action of
Justine A. Keovilay, Jason W. Hoskins, Jean‐Pierre Kinet, Thomas C. Lines, Daniel R. Kennedy   +4 more
wiley   +1 more source

The Urokinase-Type Plasminogen Activator Contributes to cAMP-Induced Steroidogenesis in MA-10 Leydig Cells [PDF]

, 2022
Zoheir B. Demmouche, Jacques Tremblay
openalex   +1 more source

Urokinase prophylactic anticoagulation in children with nephrotic syndrome: a multicenter retrospective cohort study

BMC Nephrology
Objective To analyze the clinical effect of urokinase on the prevention of thrombosis in children with primary nephrotic syndrome. Methods A total of 370 children diagnosed with primary nephrotic syndrome (PNS) in the Children’s Hospital of Soochow ...
Zhen Wang, Nan Wang, Ruyue Chen, Hanyun Tang, Qiang Lin, Xiaozhong Li   +5 more
doaj   +1 more source

Efficacy of YL-1 hematoma crushing needle combined with hematoma drainage in intracerebral hemorrhage treatment

Frontiers in Medicine
ObjectiveEarly craniotomy evacuation in hematoma surgery does not significantly improve the prognosis of patients with spontaneous intracerebral hemorrhage (ICH).
Xianyong Chen, Danhong Chen, Shaonan Sun, Zhenyong Huang, Weipeng Hu, Qiangbin Zhu   +5 more
doaj   +1 more source

Human Sprouty1 Suppresses Urokinase Receptor-Stimulated Cell Migration and Invasion [PDF]

, 2013
Ahmed H. Mekkawy, David L. Morris
openalex   +1 more source

Safety and efficacy of tirofiban after intravenous thrombolysis with urokinase in patients with acute ischemic stroke

Frontiers in Neurology
IntroductionTirofiban combined with alteplase thrombolysis or endovascular therapy has been proven to improve the prognosis of patients with acute ischemic stroke (AIS).
Dian Qu, Huanhuan Liu, Zhongming Wei, Yao Cheng, Yutong Fei, Jinghan Xu, Xiuyu Lv, Wendi Li   +7 more
doaj   +1 more source

Probing Cholesterol-Dependence of Integrin-Urokinase Receptor Complex Formation using Confocal Dual-Color Fluorescence Intensity Analysis [PDF]

, 2017
Yifan Ge, Jiayun Gao, Rainer Jordan, Christoph Naumann   +3 more
openalex   +1 more source

Affinity Maturation of Novel Genetically-Encoded Bicyclic Peptide Inhibitors of Urokinase-Type Plasminogen Activator

, 2023
Ylenia Mazzocato, Stefano Perin, Julia Morales‐Sanfrutos, Stefano Pluda, Zhanna Romanyuk, Giuseppe Borsato, Alessandro Scarso, Alessandro Angelini   +7 more
openalex   +1 more source