Results 101 to 110 of about 78,313 (276)

Identification of a Novel Mutation in the SERPINE1 Gene Causing Clinical Hyperfibrinolysis in English Springer Spaniel Dogs

Journal of Veterinary Internal Medicine, Volume 39, Issue 4, July/August 2025.
ABSTRACT Background A 7‐month‐old female spayed English Springer Spaniel (ESS) was evaluated for spontaneous hemoperitoneum. Hyperfibrinolysis was identified on thromboelastography. Hypothesis/Objectives To identify a genetic mutation causing congenital hyperfibrinolysis in the proband and evaluate the prevalence of the mutation in the ESS breed ...
Kelley Kilpatrick, Jonah N. Cullen, Farah F. Almeer, LeeAnn Higgins, Todd Markowski, Marjory Brooks, Steven G. Friedenberg, Molly Racette   +7 more
wiley   +1 more source

Temporary inferior vena cava filter combined with catheter contact thrombolysis in the treatment of acute pulmonary embolism secondary to pelvic vein thrombosis

Zhongguo linchuang yanjiu
Objective To investigate the treatment methods and efficacy of acute pulmonary embolism. Methods The diagnosis and treatment information of 8 patients with APE secondary to pelvic vein thrombosis admitted by the Changsha First Hospital from 2020 to 2021 ...
LIU Yangzhen, YAN Peng
doaj   +1 more source

Development of immunoassays for human urokinase [PDF]

Radioimmune assays (RIA) and enzyme linked immune assays for measurement of pro-urokinase and the two active forms of the enzyme were developed. Polyclonal and monoclonal antibodies, with desired specificities against preselected synthetic regions of ...
Atassi, M. Zouhair
core   +1 more source

Barnes Hospital Bulletin [PDF]

, 1967
https://digitalcommons.wustl.edu/bjc_barnes_bulletin/1024/thumbnail ...

core   +1 more source

Prognostic Value of the TLM3 Biomarker Panel for Early Fibrosis Development in MASLD Within the General Population

Liver International, Volume 45, Issue 7, July 2025.
ABSTRACT Background & Aims Fibrotic MASLD is associated with increased morbidity and mortality, often remaining asymptomatic until advanced stages of disease. Predicting fibrosis onset and progression would improve risk stratification and treatment allocation.
Koen C. van Son, Jelle C. B. C. de Jong, Serdar Özsezen, Martien P. M. Caspers, Quinten J. J. Augustijn, Jessica Snabel, Henrike Galenkamp, Henrike M. Hamer, Anne‐Marieke van Dijk, Arianne van Koppen, Anne Linde Mak, Bert‐Jan van den Born, Max Nieuwdorp, Joost P. H. Drenth, Lise Lotte Gluud, Maarten E. Tushuizen, Roeland Hanemaaijer, Lars Verschuren, Adriaan G. Holleboom   +18 more
wiley   +1 more source

Urokinase-type Plasminogen Activator and Plasminogen Activator Inhibitor Induction by Etoposide in a Glioblastoma Cell Strain

Food Technology and Biotechnology, 2002
Urokinase plasminogen activator (uPA) and its inhibitors (PAI) are elements of plasminogen activation system, a proteolytic system involved in many physiological and patological processes.
Branko Brdar, Maja Matulić
doaj  

Non-Surgical Bleeding and Transurethral Resection of the Prostate (TURP) Syndrome after TURP Surgery: A Case Report and Literature Review

Pathophysiology
Patients undergoing transurethral resection of the prostate (TURP) surgery can develop TURP syndrome and post-TURP bleeding. Post-TURP bleeding can be surgical, from arteries or venous sinuses, or non-surgical, due to coagulopathy preventing clot ...
Akram M. Eraky, Sidney C. Rubenstein, Adnan Khan, Yasser Mokhtar, Nicole M. Gregorich   +4 more
doaj   +1 more source

SerpinB2 regulates stromal remodelling and local invasion in pancreatic cancer [PDF]

, 2017
Pancreatic cancer has a devastating prognosis, with an overall 5-year survival rate of ~8%, restricted treatment options and characteristic molecular heterogeneity.
A H Allam, A Neesse, A Neesse, A V Biankin, A Xue, AB Seymour, AD Rhim, AK Witkiewicz, AM LeBeau, AR Shekouh, AV Biankin, B Hinz, BC Ozdemir, BJ Cochran, BJ Cochran, C Gaggioli, C Vennin, D Croucher, D Goldstein, D Herrmann, D Herrmann, D Mahadevan, D N Saunders, D Telgenhoff, DD Von Hoff, DR Croucher, DR Croucher, E Cerami, F Al-Ejeh, G Finak, H Shiomi, HW Smith, I Garrido-Laguna, J Condeelis, J Gao, J Gore, J Lee, J Li, J P Morton, J R W Conway, JA Lee, JJ Lee, JP Morton, K Kessenbrock, K L Vine, L Harris, M C Lucas, M J Cowley, M Nobis, M Pajic, M Pinese, M Ranson, MJ Duffy, ML Nyström, N L E Harris, N Waddell, P Bailey, P Carmeliet, P Timpson, P Timpson, R Cicchi, R F Shearer, R Kalluri, R Smith, RF Shearer, RG Rowe, RL Siegel, S Nurmenniemi, S Ulisse, SC Barry, SR Hingorani, SR Hingorani, TK Stutchbury, WA Schroder, Y Takeuchi, ZS Boyd, Ö Babur   +76 more
core   +1 more source

Growth Arrest and DNA Damage Protein 45A Promotes PPRV Replication via the Downregulation of TBK1 Expression to Inhibit IFN‐β Signaling Pathway

The FASEB Journal, Volume 39, Issue 12, 30 June 2025.
A working model of host protein GADD45A regulation of PPRV replication. During PPRV infection, the viral protein V forms a complex with GADD45A in the cytoplasm. GADD45A interacts with TBK1 and inhibits its expression. Similarly, V also interacts with TBK1 and inhibits TBK1 expression.
Haiyan Ding, Wenping Yang, Jinyan Wu, Junhuang Wu, Mengyi Wang, Jijun He, Ligang Yuan, Haixue Zheng, Youjun Shang, Dan Li   +9 more
wiley   +1 more source

Cardiovascular Disease Biomarkers and suPAR in Predicting Decline in Renal Function: A Prospective Cohort Study

Kidney International Reports, 2017
Soluble urokinase-type plasminogen activator receptor (suPAR) strongly predicts outcomes and incident chronic kidney disease (CKD) in patients with cardiovascular disease (CVD). Whether the association between suPAR and CKD is a reflection of its overall
Salim S. Hayek, Yi-An Ko, Mosaab Awad, Hina Ahmed, Brandon Gray, Kareem Mohammed Hosny, Hiroshi Aida, Melissa J. Tracy, Changli Wei, Sanja Sever, Jochen Reiser, Arshed A. Quyyumi   +11 more
doaj   +1 more source