Results 21 to 30 of about 43,123 (212)

Balloon-Assisted Thrombectomy and Intrasinus Urokinase Thrombolysis for Severe Cerebral Venous Sinus Thrombosis

Frontiers in Neurology, 2021
Background: Current clinical guidelines recommend systemic anticoagulation as the initial treatment for severe cerebral venous sinus thrombosis (CVST).
Jiansheng Yang, Hongyang Wang, Yanxing Chen, Minjian Qiu, Baorong Zhang, Zhicai Chen   +5 more
doaj   +1 more source

Sequential intrapleural administration of fibrinolytic drugs and dornase alfa for empyema management. Treatment protocol based on its physicochemical stability [PDF]

Farmacia Hospitalaria, 2020
Objective: Intrapleural administration of fibrinolytics and dornase alfa has been shown in randomized studies to be able to reduce both the need for surgical debridement of empyema and the average hospital stay.
Carla Bastida, Carlota Salazar-Santander, Dolors Soy, David Sánchez, Carmen Díez, Joan Ramón Badia   +5 more
doaj   +1 more source

Malignant progression of liver cancer progenitors requires lysine acetyltransferase 7–acetylated and cytoplasm‐translocated G protein GαS

Hepatology, EarlyView., 2022
KAT7‐acetylated and cytoplasm‐translocated G‐protein GαS enhances IL‐6 effect and drives HCC progenitor cell progression. Abstract Background and Aims Hepatocarcinogenesis goes through HCC progenitor cells (HcPCs) to fully established HCC, and the mechanisms driving the development of HcPCs are still largely unknown.
Ye Zhou, Kaiwei Jia, Suyuan Wang, Zhenyang Li, Yunhui Li, Shan Lu, Yingyun Yang, Liyuan Zhang, Mu Wang, Yue Dong, Luxin Zhang, Wannian Zhang, Nan Li, Yizhi Yu, Xuetao Cao, Jin Hou   +15 more
wiley   +1 more source

Case report: Ultrasound-guided percutaneous drainage combined with lavage using urokinase: An economical and effective treatment for muscular hematomas in hemophiliacs

Frontiers in Surgery, 2023
This was an initial effort to treat hemophiliac hematoma by ultrasound-guided intratumoral drainage and lavage with urokinase after adequate supplementation of coagulation factors.
Hao Liu, Cong Xu, Weizhen Wang, Bin Chen, Jing Sun, Xiaoqin Feng, Yaru Zhang, Fei Ma, Lingli Du, Yang Gao, Yingjia Li   +10 more
doaj   +1 more source

Intrapleural Fibrinolysis with Urokinase versus Alteplase in Complicated Pleural Effusions and Empyema: A Prospective Randomized Controlled Trial [PDF]

Tuberculosis and Respiratory Diseases
Background Intrapleural fibrinolytic therapy (IPFT) has been used as an effective agent since 1949 for managing complicated pleural effusion and empyema. Several agents, such as streptokinase, urokinase (UK), and recombinant tissue plasminogen activator (
Sudipt Adhikari, Vikas Marwah, Robin Choudhary, Indermani Pandey, Tentu Ajai Kumar, Virender Malik, Arpita Pemmaraju, Shrinath Vasudevan, Suraj Kapoor   +8 more
doaj   +1 more source

Fibrinolysis versus thoracoscopy: Comparison of results in empyema management in the child

Annals of Thoracic Medicine, 2022
OBJECTIVE: The objective of this study is to compare the outcome of treatment with drainage and urokinase (UK) versus thoracoscopy (TS) in pleural empyema secondary to complicated pneumonia.
Maria Rosa Ibarra Rodriguez, Jose Ignacio Garrido Pérez, Fernando Vázquez Rueda, Francisco Javier Murcia Pascual, Sandra Rocio Wiesner Torres, Rosa Maria Paredes Esteban   +5 more
doaj   +1 more source

Role of multidomain structure of urokinase in regulation of growth and remodeling of vessels [PDF]

The Ukrainian Biochemical Journal, 2013
Urokinase type plasminogen activator, or urokinase (uPA), is a multifunctional protein which plays special regulatory role in the vascular wall and can actuate the proteolytic and signal cascades.
V. A. Tkachuk, O. S. Plekhanova, I. B. Beloglazova, E. V. Parfenova   +3 more
doaj   +1 more source

The role of the host—Neutrophil biology

Periodontology 2000, EarlyView., 2023
Abstract Neutrophilic polymorphonuclear leukocytes (neutrophils) are myeloid cells packed with lysosomal granules (hence also called granulocytes) that contain a formidable antimicrobial arsenal. They are terminally differentiated cells that play a critical role in acute and chronic inflammation, as well as in the resolution of inflammation and wound ...
Iain L. C. Chapple, Josefine Hirschfeld, Alpdogan Kantarci, Asaf Wilensky, Lior Shapira   +4 more
wiley   +1 more source

Bridging a Century-Old Problem: The Pathophysiology and Molecular Mechanisms of HA Filler-Induced Vascular Occlusion (FIVO)—Implications for Therapeutic Interventions

Molecules, 2022
Biocompatible hyaluronic acid (HA, hyaluronan) gel implants have altered the therapeutic landscape of surgery and medicine, fostering an array of innovative products that include viscosurgical aids, synovial supplements, and drug-eluting nanomaterials ...
Danny J. Soares
doaj   +1 more source

Minimally Invasive Technique for Spontaneous Intraparenchymal Hemorrhage

Indian Journal of Neurosurgery
Objective The aim of this study was to introduce a cost-effective and less invasive method for the evacuation of intraparenchymal hemorrhage (IPH).
Himanshu Raval, Kalpesh Shah, Mona Bhatt
doaj   +1 more source