Results 71 to 80 of about 1,484,561 (230)

The Roles of Fibrinolytic Factors in Bone Destruction Caused by Inflammation

Cells
Chronic inflammatory diseases, such as rheumatoid arthritis, spondyloarthritis, systemic lupus erythematosus, Crohn’s disease, periodontitis, and carcinoma metastasis frequently result in bone destruction.
Yosuke Kanno
doaj   +1 more source

Circulating Soluble Urokinase-Type Plasminogen Activator Receptor in Obstructive Sleep Apnoea

Medicina, 2020
Background and Objectives: Obstructive sleep apnoea (OSA) is associated with heightened systemic inflammation and a hypercoagulation state. Soluble urokinase-type plasminogen activator receptor (suPAR) plays a role in fibrinolysis and systemic ...
Renata Marietta Bocskei, Martina Meszaros, Adam Domonkos Tarnoki, David Laszlo Tarnoki, Laszlo Kunos, Zsofia Lazar, Andras Bikov   +6 more
doaj   +1 more source

Periodontitis and Diabetes: Mechanistic Evidence of a Circular Relationship

Journal of Periodontal Research, EarlyView.
This narrative review aimed to explore the underlying mechanisms that connect periodontitis to diabetes (and vice versa) and that influence disease susceptibility, progression and response to treatment. ABSTRACT The circular relationship between periodontitis and diabetes mellitus is one of the most established oral‐systemic links.
Philip M. Preshaw, Ren Jie Jacob Chew, Charlene Enhui Goh, Ali A. Abdulkareem, Dana T. Graves   +4 more
wiley   +1 more source

Ligand Binding Regions in the Receptor for Urokinase-type Plasminogen Activator [PDF]

Journal of Biological Chemistry, 2001
The interaction between urokinase plasminogen activator (uPA) and its cellular receptor (uPAR) is a key event in cell surface-associated plasminogen activation, relevant for cell migration and invasion. In order to define receptor recognition sites for uPA, we have expressed uPAR fragments as fusion products with the minor coat protein on the surface ...
O D, Liang, T, Chavakis, S M, Kanse, K T, Preissner   +3 more
openaire   +2 more sources

Soluble urokinase plasminogen activator receptor (suPAR) (ng/ml) in blood donors according to sex and age.

, 2014
Soluble urokinase plasminogen activator receptor (suPAR) (ng/ml) in blood donors according to sex and age.
Christian Thorball (569556), Eva Haastrup (423039), Lars Vedel Kessing (176727), Jesper Eugen-Olsen (39433), Henrik Ullum (308103), Katrine Grau (349910)   +5 more
core   +1 more source

Soluble Urokinase Plasminogen Activator Receptor: A Risk Factor for Carotid Plaque, Stroke, and Coronary Artery Disease

, 2014
Recent studies indicate that the urokinase system could have an important role in atherogenesis and plaque rupture. The relationships among the soluble urokinase plasminogen activator receptor (suPAR), carotid plaque, and incidence of ischemic stroke and
Persson, Margaretha,, Engström, Gunnar,, Hamrefors, Viktor,, Hedblad, Bo,, Östling, Gerd,, Smith, Gustav,, Melander, Olle,, Lund University.   +7 more
core   +2 more sources

Rhenium‐Based β‐Galactosidase Probe Allows Senescence Profiling by Mass Cytometry

Angewandte Chemie, Volume 138, Issue 42, 12 October 2026.
Senescence‐associated β‐galactosidase (SA‐β‐Gal) activity is a widely accepted biomarker of cellular senescence, yet its integration with other senescence markers has been limited by available detection methods. Here, we introduce ReGal, a mass cytometry‐compatible SA‐β‐Gal activity probe that can be multiplexed with established markers of senescence ...
Adam Tam, Kris Elbein, Aleida G. Gonzalez, Edgar A. Arriaga, Mark Nitz   +4 more
wiley   +2 more sources

Predicting Mortality in African Americans With Type 2 Diabetes Mellitus: Soluble Urokinase Plasminogen Activator Receptor, Coronary Artery Calcium, and High‐Sensitivity C‐Reactive Protein

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2018
BackgroundType 2 diabetes mellitus is a major risk factor for cardiovascular disease; however, outcomes in individual patients vary. Soluble urokinase plasminogen activator receptor (suPAR) is a bone marrow–derived signaling molecule associated with ...
Salim S. Hayek, Jasmin Divers, Mohamad Raad, Jianzhao Xu, Donald W. Bowden, Melissa Tracy, Jochen Reiser, Barry I. Freedman   +7 more
doaj   +1 more source

How I Investigate Bleeding Disorders of Unknown Cause: Current Diagnostic Pathways and Gaps in Laboratory Investigation

International Journal of Laboratory Hematology, Volume 48, Issue 6, Page 1289-1297, December 2026.
ABSTRACT Bleeding disorder of unknown cause (BDUC) constitutes the largest group of patients presenting with a mild‐to‐moderate bleeding tendency in tertiary care settings. Their clinical bleeding phenotype is characterized by mucocutaneous bleeding, as well as bleeding following surgical challenges or childbirth, and is associated with impaired health‐
Dino Mehic, Faris Karaselimovic, Tim Dreier, Johanna Gebhart   +3 more
wiley   +1 more source

Video from Structure-based design of an urokinase-type plasminogen activator receptor–derived peptide inhibiting cell migration and lung metastasis

, 2009
Video from Structure-based design of an urokinase-type plasminogen activator receptor–derived peptide inhibiting cell migration and lung ...
Mario De Rosa (15040481), Liliana Lista (2709868), Giuseppina Votta (2141533), Maria Vincenza Carriero (8713431), Renato Franco (184143), Maria Teresa Masucci (15040478), Maria Patrizia Stoppelli (133653), Katia Bifulco (133627), Vincenzo Pavone (133641), Claudio Arra (133331), Antonio Barbieri (458558), Immacolata Longanesi-Cattani (133632), Ornella Maglio (4379920)   +12 more
core   +1 more source