Results 91 to 100 of about 1,484,561 (230)

A Single Smart Nanomaterial for Near‐Infrared‐Switchable Theranostics of Hemorrhage and Thrombosis via Photoacoustic Imaging

Small Science, Volume 6, Issue 11, November 2026.
A smart nanomaterial integrating Ag single atoms and nanoparticles on NiFe‐layered double hydroxides enables NIR‐switchable hemostasis and thrombolysis via photoelectric and photothermal effects. This platform allows real‐time photoacoustic imaging of active bleeding and exhibits rapid in vivo clearance, offering a dynamic theranostic strategy for ...
Yi Ye, Zhilu Sun, Daofu Wu, Jun’an Lai, Mingyue Yang, Zhiqiong Luo, Sha Cheng, Suwen Yang, Hong Zeng, Yinghui Li, Faguang Kuang, Baofei Sun, Wenxia Zhang, Xiaosheng Tang, Heng Luo, Guofeng Wu   +15 more
wiley   +1 more source

Akhirin Preserves Hemostatic Wound Repair Through Non-Hematopoietic Regulation of the Vascular Injury Microenvironment

Journal of Developmental Biology
Hemostasis and wound healing are highly coordinated processes that involve rapid clot formation followed by controlled remodeling of the injured tissue microenvironment.
Mohammad Badrul Anam, Mikiko Kudo, Terumasa Umemoto, Keisuke Yamashita, Rie Kawano, Kunimasa Ohta   +5 more
doaj   +1 more source

A covalent peptide engager approach to equip immunotherapeutic monoclonal and pan IgG serum antibodies with new tumour‐targeting function

British Journal of Pharmacology, Volume 183, Issue 22, Page 6685-6703, November 2026.
Abstract Background and Purpose Site‐specific antibody modification is a useful chemical strategy to elaborate antibody therapeutic function. Conventional lysine‐ or cysteine‐based conjugation methods generate heterogeneous products, while protein engineering approaches are resource‐intensive.
Karolina Krygier, Sandra Szu‐Wei Hwang, Anthony F. Rullo   +2 more
wiley   +1 more source

Abstract 17717: Association of Depression with Soluble Urokinase- Type Plasminogen Activator Receptor and Other Markers of Inflammation and Immunity

, 2012
Background: Depression, coronary artery disease (CAD), and inflammation may share pathophysiological links. Soluble urokinase-type plasminogen activator receptor (suPAR) is a biomarker of inflammat..
Al Kassem, Hatem, Ghasemzadeh, Nima, Vaccarino, Viola, Manocha, Pankaj, Kumar, Saket, Shah, Amit J., Thorball, Christian W., Sher, Salman, Hammadah, Muhammad, Garcia-Bengochea, Youssef O, Niaz, Adil, Patel, Riyaz S., Syed, Hamid, Veledar, Emir, Tahhan, Ayman Samman, Eapen, Danny J., Kelli, Heval M., Farook, Naureen, Le, Ngoc-Anh, Pimple, Pratik, Nanjundappa, Ravi, Obideen, Malik, Quyyumi, Arshed A., Kabani, Sarah S, Raison, Charles L, Zafari, Rostam, Sperling, Laurence S., Pielak, Tomasz   +27 more
core   +1 more source

Hemostatic balance on the surface of leukemic cells: the role of tissue factor and urokinase plasminogen activator receptor

Haematologica, 2005
BACKGROUND AND OBJECTIVES: The frequency of thrombotic complications is increased in patients with acute leukemia. Since coagulation processes take place on cell membranes, we hypothesized that expression of coagulation proteins on blast membrane could ...
Y Nadir, T Katz, G Sarig, R Hoffman, A Oliven, JM Rowe, B Brenner   +6 more
doaj  

Effect of Plasma Soluble Urokinase-Type Plasminogen Activator Receptor and Plasminogen Activator Inhibitor-1 Levels in the Plasma of Babylon Women with Breast Cancer

Medical Journal of Babylon
Background: Worldwide, the occurrence of breast cancer is elevated as well as the number of mortality in women cancers. The movement of cancer cells from the first stage and invasion of the surrounding tissue are called cancer metastasis.
Sheerin H. Abbas, Zinah Abbass Ali, Alaa Sadiq Alaawad   +2 more
doaj   +1 more source

Surface α-enolase promotes extracellular matrix degradation and tumor metastasis and represents a new therapeutic target.

PLoS ONE, 2013
In previous research, we found α-enolase to be inversely correlated with progression-free and overall survival in lung cancer patients and detected α-enolase on the surface of lung cancer cells.
Kuan-Chung Hsiao, Neng-Yao Shih, Hsun-Lang Fang, Tze-Sing Huang, Ching-Chuan Kuo, Pei-Yi Chu, Yi-Mei Hung, Shao-Wen Chou, Yi-Yuan Yang, Gee-Chen Chang, Ko-Jiunn Liu   +10 more
doaj   +1 more source

Interleukin‐12: Central Roles in Immune Regulation and Disease Therapy

Immunology &Cell Biology, Volume 104, Issue 10, Page 996-1014, November‐December 2026.
IL‐12 levels are tightly regulated to balance effective protective immunity against infections and cancer with the risk of excessive inflammation and autoimmune disease. Both insufficient and excessive IL‐12 activity can therefore be detrimental, highlighting the importance of precisely controlling its production and signaling. ABSTRACT Interleukin‐12 (
Anthi Psoma, Geert van den Bogaart
wiley   +1 more source

Urokinase-type plasminogen activator receptor

, 2003
A polypeptide presenting an epitope cross-reactive with an epitope of urokinase-type plasminogen activator receptor, and/or having uPA binding activity, is described.
Pollanen,, Jari, Vaheri,, Antti, Dano, Keld, Pyke, Charles, Masucci, Maria, Teresa, Roldan, Ann, Louring, Behrendt, Niels, Ploug, Michael, Cubellis, Maria, Vittoria, Ronne, Ebbe, Tapiovaara,, Hannele, Lund Leif, Roge, Patthy, Laszlo, Salonen,, Eeva-Marjatta, Moller Lisbeth, Birk, Ellis, Vincent, Stephens, Ross, W, Blasi, Francesco, Appella,, Ettore, Schleuning,, Wolf-Dieter, Kristensen, Peter   +20 more
core  

Lipoprotein(a), Endothelial Dysfunction and Cardiovascular Disease

Journal of Cellular and Molecular Medicine, Volume 30, Issue 21, November 2026.
ABSTRACT Lipoprotein(a) (Lp(a)) is a particle similar to low‐density lipoprotein cholesterol and is associated with apolipoprotein (A). High Lp(a) levels are a genetic, independent risk factor for atherosclerotic cardiovascular disease (ASCVD). Endothelial cells, which form the continuous lining of the cardiovascular system, are crucial for vascular ...
Xianghui Zhou, Xiyuan Fang, Xin Zhou, Zhao Zhang, Yu Hu, Zhipeng Cheng   +5 more
wiley   +1 more source