Results 111 to 120 of about 25,610 (245)

The physiological and pathological effects of sphingolipid metabolism and signaling in the central nervous system

open access: yesBrain Pathology, Volume 36, Issue 1, January 2026.
Sphingolipids are vital components of cell membranes. Metabolic disruptions of sphingolipids, including ceramide and sphingosine‐1‐phosphate, are linked to neurological disorders. This article summarizes the classification, structure, and metabolic processes of sphingolipids, and the physiological and pathological effects of sphingolipid metabolism and
Tian Li   +7 more
wiley   +1 more source

BIOCHEMICAL MARKERS OF ENDOTHELIAL DYSFUNCTION AND HEMOSTASIS IN ATHEROSCLEROSIS AND THE GENES RESPONSIBLE FOR THEIR REGULATION

open access: yesАтеросклероз, 2017
The review systematized modern concepts of markers of endothelial dysfunction and disorders of hemostasis (asymmetric dimethylarginine, endothelin 1, adhesive ICAM and VCAM molecules, apolipoproteins, antithrombin III, receptor of urokinase plasminogen ...
E. V. Stryukova   +2 more
doaj  

Expression of urokinase plasminogen activator and its receptor during acute renal allograft rejection [PDF]

open access: bronze, 2003
Joris J. T. H. Roelofs   +7 more
openalex   +1 more source

UK Biobank: Transforming drug discovery and precision medicine

open access: yesBritish Journal of Pharmacology, Volume 183, Issue 2, Page 234-248, January 2026.
UK Biobank is a large‐scale, prospective study with extensive genetic and phenotypic data on half a million individuals. Volunteers, aged between 40 and 69 years, were recruited between 2006 and 2010 from the general population of the United Kingdom.
Jelena Bešević   +11 more
wiley   +1 more source

Soluble Urokinase Receptor as a Promising Marker for Early Prediction of Outcome in COVID-19 Hospitalized Patients. [PDF]

open access: yesJ Clin Med, 2021
Napolitano F   +11 more
europepmc   +1 more source

Principal mechanisms of extracellular matrix‐mediated cell–cell communication in physiological and tumor microenvironments

open access: yesThe FEBS Journal, Volume 293, Issue 1, Page 26-41, January 2026.
Intracellular communication controls the processing of generated signals so that every cell type can successfully respond. The extracellular matrix (ECM) is a fundamental regulator of cell communication and signaling through the strict orchestration and functions of its bioactive components.
Zoi Piperigkou   +6 more
wiley   +1 more source

From Neuron‐Centric to Glia‐Centric: How Aging Glial Networks Drive Neurodegenerative Disease

open access: yesJournal of Neurochemistry, Volume 170, Issue 1, January 2026.
During aging, progressive alterations in glial networks reshape intercellular communication within the central nervous system. In the young brain, astrocytes and microglia actively regulate metabolic, immune, and synaptic processes that sustain neural circuit stability.
Lívia de Sá Hayashide   +5 more
wiley   +1 more source

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