Results 131 to 140 of about 25,610 (245)

Inhibition of Growth and Induction of Apoptosis of Human Prostate Cancer Cells by Enzymatic Blockage of Kallikreins

Prostate Cancer, Volume 2026, Issue 1, 2026.
Background Most therapy options for castration‐resistant prostate cancer (CRPCa) target the androgen axis. Human kallikrein–related peptidase (KLK) 2, a serine protease, is a downstream target gene of the androgen receptor (AR) involved in cancer progression, but also known to have an AR‐independent function. Tissue KLKs, especially KLK2, are promising
Fabienne Lehner, Souzan Salemi, Christopher Millan, Christoph Kündig, Daniel Eberli, Harleen Khatra   +5 more
wiley   +1 more source

SAMP14, a Novel, Acrosomal Membrane-associated, Glycosylphosphatidylinositol-anchored Member of the Ly-6/Urokinase-type Plasminogen Activator Receptor Superfamily with a Role in Sperm-Egg Interaction [PDF]

, 2003
Jagathpala Shetty, Michael J. Wolkowicz, Laura Digilio, Kenneth L. Klotz, Friederike L. Jayes, Alan B. Diekman, V. Anne Westbrook, Erin M. Farris, Zhonglin Hao, Scott A. Coonrod, Charles J. Flickinger, John C. Herr   +11 more
openalex   +1 more source

Data from A Urokinase Receptor–Derived Peptide Inhibiting VEGF-Dependent Directional Migration and Vascular Sprouting

, 2023
Katia Bifulco, Immacolata Longanesi-Cattani, Eleonora Liguori, Claudio Arra, Domenica Rea, Maria Teresa Masucci, Mario De Rosa, Vincenzo Pavone, Maria Patrizia Stoppelli, Maria Vincenza Carriero   +9 more
openalex   +1 more source

Supplementary Figure 1 from A Urokinase Receptor–Derived Peptide Inhibiting VEGF-Dependent Directional Migration and Vascular Sprouting

, 2023
Katia Bifulco, Immacolata Longanesi-Cattani, Eleonora Liguori, Claudio Arra, Domenica Rea, Maria Teresa Masucci, Mario De Rosa, Vincenzo Pavone, Maria Patrizia Stoppelli, Maria Vincenza Carriero   +9 more
openalex   +1 more source

Targeting the urokinase plasminogen activator receptor enhances gene transfer to human airway epithelia [PDF]

, 2000
Paola T. Drapkin, Catherine R. O’Riordan, Su Yi, John A. Chiorini, Jonathan Cardella, Joseph Zabner, Michael J. Welsh   +6 more
openalex   +1 more source

Cancer cells overexpress mRNA of urokinase-type plasminogen activator, its receptor and inhibitors in human non-small-cell lung cancer tissue: Analysis by Northern blotting andin situ hybridization [PDF]

, 1998
Sumihito Morita, Atsuhiko Sato, Hiroshi Hayakawa, Hayato Ihara, Tetsumei Urano, Yumiko Takada, Akikazu Takada   +6 more
openalex   +1 more source

Supplemental Figure S1 from A Urokinase Receptor–Bim Signaling Axis Emerges during EGFR Inhibitor Resistance in Mutant EGFR Glioblastoma

, 2023
Jill Wykosky, Jingjing Hu, German G. Gomez, Tiffany Taylor, Genaro R. Villa, Donald Pizzo, Scott R. VandenBerg, Amy Haseley Thorne, Clark C. Chen, Paul S. Mischel, Steven L. Gonias, Webster K. Cavenee, Frank B. Furnari   +12 more
openalex   +1 more source

Bispecific Targeting of EGFR and Urokinase Receptor (uPAR) Using Ligand-Targeted Toxins in Solid Tumors. [PDF]

Biomolecules, 2020
Oh F, Modiano JF, Bachanova V, Vallera DA.   +3 more
europepmc   +1 more source

Helicobacter pylori Colonization Drives Urokinase Receptor (uPAR) Expression in Murine Gastric Epithelium During Early Pathogenesis. [PDF]

Microorganisms, 2020
Alpízar-Alpízar W, Skindersoe ME, Rasmussen L, Kriegbaum MC, Christensen IJ, Lund IK, Illemann M, Laerum OD, Krogfelt KA, Andersen LP, Ploug M.   +10 more
europepmc   +1 more source

The urokinase receptor/uPAR is a major effector of p53 gain-of-function mutations in gemcitabine-treated pancreatic ductal adenocarcinoma. [PDF]

J Biol Chem
Zampieri C, Kouhmareh K, Sartipdolagh P, Azmoon P, Klemke RL, Gonias SL.   +5 more
europepmc   +1 more source