Results 211 to 220 of about 2,335,681 (277)

Profibrinolytic Factors and Cancer Progression, Metastasis, and Survival. [PDF]

Arterioscler Thromb Vasc Biol
Hisada Y, Mackman N.
europepmc   +1 more source

WCN25-2746 Urokinase plasminogen activator receptor upregulation in lupus nephritis associates with distinct interferon hub genes in stressed podocytes

Björn Tampe, Michael Zeisberg
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Soluble Urokinase Plasminogen Activator Receptor (suPAR) Predicts 28-Day and 90-Day Mortality in Emergency Department Patients with Chest Pain, Dyspnoea, or Abdominal Pain. [PDF]

Diagnostics (Basel)
Gavelli F, Giolitti FM, Vidali M, Montersino M, Bertoli M, Molinari L, Baldrighi M, Beltrame M, Sainaghi PP, Bellan M, Patrucco F, Avanzi GC, Castello LM.   +12 more
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Circulating extracellular vesicles predict outcome in patient undergoing transjugular intrahepatic portosystemic shunt (TIPS) placement. [PDF]

Sci Rep
Loosen SH, Hansen FJ, Schatilow D, Wirtz T, Reuken PA, Bode J, Kunstein A, Vucur M, Reißing J, Flügen G, Castoldi M, Stallmach A, Luedde T, Bruns T, Roderburg C.   +14 more
europepmc   +1 more source

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The Urokinase Receptor Interactome

Current Pharmaceutical Design, 2011
The urokinase receptor (uPAR) was originally identified as the membrane receptor of the serine protease urokinase (uPA), thereby implicated in the plasminogen activation cascade and regulation of pericellular proteolysis. Later on, vitronectin was showed to be another major ligand providing uPAR with a role in cell adhesion.
Gabriele, Eden, Marco, Archinti, Federico, Furlan, Ronan, Murphy, Bernard, Degryse   +4 more
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The kringle stabilizes urokinase binding to the urokinase receptor

Blood, 2003
AbstractThe structural basis of the interaction between single-chain urokinase-type plasminogen activator (scuPA) and its receptor (uPAR) is incompletely defined. Several observations indicated the kringle facilitates the binding of uPA to uPAR. A scuPA variant lacking the kringle (ΔK-scuPA) bound to soluble uPAR (suPAR) with the similar “on-rate” but ...
Khalil, Bdeir, Alice, Kuo, Bruce S, Sachais, Ann H, Rux, Yasmina, Bdeir, Andrew, Mazar, Abd Al-Roof, Higazi, Douglas B, Cines   +7 more
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The receptor for urokinase‐plasminogen activator

Journal of Cellular Biochemistry, 1986
AbstractMany human cells and cell lines possess a specific receptor that binds urokinase plasminogen activator (uPA) with an affinity of about 10−10 M. Bound enzyme is not internalized, is slowly dissociated, and retains its enzymatic activity. The amino acid sequence of uPA responsible for receptor binding is located within the first 35 aminoterminal ...
Francesco Blasi, M. Patrizia Stoppelli, CUBELLIS, MARIA VITTORIA   +2 more
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