Results 51 to 60 of about 27,231 (235)
Исследования и практика в медицине, 2022 Purpose of the study. An analysis of the changes in components of the urokinase system in the brain of urokinase gene-knockout mice (uPA-/-) with B16/F10 melanoma growing alone and together with chronic neurogenic pain (CNP).Materials and methods.
E. M. Frantsiyants +7 more
doaj +1 more source
Fibrinolytics: from the thrombolysis to the processes of blood vessels growth and remodeling, neurogenesis, carcinogenesis and fibrosis [PDF]
Терапевтический архив, 2019 One of the most outstanding scientific achievements in the thrombolysis is the development and administration of fibrinolysin - the first Soviet drug that lyses blood clots.
V A Tkachuk +7 more
doaj +1 more source
Neural Regeneration Research, 2020 The last two decades have witnessed a rapid decrease in mortality due to acute cerebral ischemia that paradoxically has led to a rapid increase in the number of patients that survive an acute ischemic stroke with various degrees of disability ...
Manuel Yepes
doaj +1 more source
PLAUR (plasminogen activator, urokinase receptor) [PDF]
, 2010 Review on PLAUR (plasminogen activator, urokinase receptor), with data on DNA, on the protein encoded, and where the gene is ...
B Jacobsen +5 more
core +1 more source
Augmented Urokinase Receptor Expression in Atheroma [PDF]
Arteriosclerosis, Thrombosis, and Vascular Biology, 1995 Abstract Smooth muscle cell proliferation and migration into neointima are hallmarks of atherogenesis. However, mechanisms responsible have not yet been fully elucidated. One potential mediator of both smooth muscle cell proliferation and migration is activation of plasminogen by activators bound to receptors on cells within ...
H, Noda-Heiny, A, Daugherty, B E, Sobel
openaire +2 more sources
The role of soluble urokinase plasminogen activator receptor (suPAR) in patients with cancer: a review of the current literature [PDF]
Medicinski Glasnik, 2022 Aim Several biomarkers are currently used as diagnostic and prognostic tools in patients with cancer. Soluble urokinase plasminogen activator receptor (suPAR) is elevated in acute and chronic inflammatory procedures and several observational studies ...
Themistoklis Paraskevas +13 more
doaj +1 more source
Retro-inverso Urokinase Receptor Antagonists for the Treatment of Metastatic Sarcomas. [PDF]
Sci Rep, 2017 The development of metastases is a multistep process that requires the activation of physiological and biochemical processes that govern migration, invasion and entry of metastatic cells into blood vessels.
Carriero MV +13 more
europepmc +2 more sources
Urokinase receptor genotypes in colorectal cancer [PDF]
Carcinogenesis, 1998 A previous study has reported a high frequency of rare alleles of the urokinase-type plasminogen activator receptor (uPAR) in a set of 15 colorectal cancer (CRC) cell lines. Our study investigated uPAR gene variation in 92 CRC patients and in tumour DNA from a subset of 69 patients using the PLAUR-IVS3 marker located in an intron of this gene.
M, Kohonen-Corish +3 more
openaire +2 more sources
Advanced Biomedical Research, 2017 Background: The objective of this study is to indicate the role of urokinase plasminogen activator receptor (uPAR), soluble uPAR (suPAR), and β1 integrin in tumor growth and invasion of lymph nodes from Hodgkin's lymphoma (HL) patients.
Shirin Kouhpayeh +5 more
doaj +1 more source
New Pieces in the Puzzle of uPAR Role in Cell Migration Mechanisms
Cells, 2020 The urokinase (uPA) receptor (uPAR) plays a key role in cell migration. We previously showed that uPAR-negative HEK-293 cells efficiently migrate toward serum but, after uPAR ectopic expression, migrate only in a uPAR-dependent manner. In fact, migration
Anna Gorrasi +5 more
doaj +1 more source