Results 21 to 30 of about 3,612 (177)
Urolithin and Reduced Urolithin Derivatives as Potent Inhibitors of Tyrosinase and Melanogenesis: Importance of the 4-Substituted Resorcinol Moiety [PDF]
International Journal of Molecular Sciences, 2021 We previously reported (E)-β-phenyl-α,β-unsaturated carbonyl scaffold ((E)-PUSC) played an important role in showing high tyrosinase inhibitory activity and that derivatives with a 4-substituted resorcinol moiety as the β-phenyl group of the scaffold resulted in the greatest tyrosinase inhibitory activity.
Sanggwon Lee +13 more
openaire +2 more sources
Interactions between Gut Microbiota and Polyphenols: New Insights into the Treatment of Fatigue
Molecules, 2022 Fatigue seriously affects people’s work efficiency and quality of life and has become a common health problem in modern societies around the world. The pathophysiology of fatigue is complex and not fully clear.
Chuanhong Luo +8 more
doaj +1 more source
Tissue deconjugation of urolithin A glucuronide to free urolithin A in systemic inflammation
Food & Function, 2019 Urolithin A glucuronide is deconjugated to free urolithin A in systemic inflammation.
Ávila-Gálvez, María Ángeles +3 more
openaire +5 more sources
Journal of Chemical Research, 2023 Urolithins are the gut microbiota metabolites of ellagitannins which are found in natural plants such as pomegranate, strawberry, and raspberry, and in nuts.
Hecheng Wang +6 more
doaj +1 more source
Molecular Nutrition & Food Research, 2016 ScopeUrolithins (Uro) are ellagic acid (EA)‐derived metabolites produced by gut microbes. There is a growing interest in the biological activities of Uro. Our aim was to evaluate the impacts of Uro on regulating triglyceride (TG) accumulation using cultures of primary human adipocytes and hepatoma Huh7 cells.Methods and resultsUroA, UroB, UroC, UroD ...
Kang, Inhae +4 more
openaire +3 more sources
Biochemistry and Biophysics Reports, 2020 Mediated by the nuclear vitamin D receptor (VDR), the hormonally active vitamin D metabolite, 1,25-dihydroxyvitamin D3 (1,25D), is known to regulate expression of genes impacting calcium and phosphorus metabolism, the immune system, and behavior ...
Sarah Livingston +9 more
doaj +1 more source
Urolithins: The Colon Microbiota Metabolites as Endocrine Modulators: Prospects and Perspectives
Frontiers in Nutrition, 2022 Selective estrogen receptor modulators (SERMs) have been used in hormone related disorders, and their role in clinical medicine is evolving. Tamoxifen and raloxifen are the most commonly used synthetic SERMs, and their long-term use are known to create ...
Ravindran Vini +8 more
doaj +1 more source
Brazilian Journal of Medical and Biological Research, 2018 An abnormality in the Lin28/let-7a axis is relevant to the progression of hepatitis B virus (HBV)-positive hepatocellular carcinoma (HCC), which could be a novel therapeutic target for this malignant tumor.
Zhenpeng Qiu +5 more
doaj +1 more source
The Compound Specific Antibacterial Activities of Major Urolithins and Their Methyl Ethers
Journal of the Turkish Chemical Society, Section A: Chemistry, 2021 The investigation of biological activities of natural products, particularly considering the secondary metabolites, continuously receives attention.
Hayrettin Ozan GÜLCAN +4 more
doaj +1 more source
Molecules, 2016 The consumption of foodstuffs yielding circulating compounds able to maintain endothelial function by improving nitric oxide (NO) bioavailability can be considered as an effective strategy for cardiovascular disease prevention.
Valentina Spigoni +7 more
doaj +1 more source