Results 81 to 90 of about 4,446 (160)
Elucidating the Anti-Inflammatory and Anti-Diabetic Properties of Urolithin Bioactive Metabolites from Pecan [PDF]
, 2023 . Pecans are a rich source of ellagitannins which are not absorbed by humans, rather they are catabolized into urolithins by human gut microbiota and enterohepatic circulation.
Bhargava, Prerna
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, 2022 Urolithin A is an active compound of gut-microbiota-derived metabolites of polyphenol ellagic acid that has anti-aging, antioxidative, and anti-inflammatory effects.
Chao, Jane C-J +13 more
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Aging of Skeletal Muscle: From Molecular Mechanisms to Therapeutic Interventions
MedComm, Volume 7, Issue 10, October 2026.Skeletal muscle aging is driven by coordinated local breakdown across myofibers, stem and stromal cells, immune and vascular compartments, and neuromuscular control. These mechanisms promote mitochondrial dysfunction, inflammation, senescence, impaired regeneration, fibrosis, myosteatosis, denervation, and functional decline.
Ting Liu, Yaomin Hu
wiley +1 more source
, 2019 © 2019 by the authors.The metabolism of dietary polyphenols ellagitannins by the gut-microbiota allows the human stratification in urolithin metabotypes depending on the final urolithins produced.
Ana Rodríguez-Varela +13 more
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Polyphenol‐Rich Foods as a Healthy and Sustainable Strategy: Mental Health and Metabolomic Profiling
Molecular Nutrition &Food Research, Volume 70, Issue 19, 15 October 2026.A 12‐week nutritional intervention with cocoa flavanols and red‐berry anthocyanins in older adults improved emotional well‐being and identified metabolomic signatures associated with the intervention through urinary metabolome profiling. ABSTRACT The so‑called demographic transition has increased the prevalence of chronic diseases in adults over 65 ...
María Lucía Gómez Nieto +6 more
wiley +1 more source
The FASEB Journal, Volume 40, Issue 18, 30 September 2026.Ellagic acid potentiates RSL3‐induced ferroptosis in PANC‐1 by suppressing the Nrf2/HO‐1 antioxidant defense axis via p38 MAPK activation and Keap1 upregulation. In PDAC cells, constitutive Nrf2/HO‐1 signaling establishes a robust antioxidant shield (GPX4, HO‐1) that limits lipid ROS accumulation and confers ferroptosis resistance.
Jianhua Bai +9 more
wiley +1 more source
, 2014 A composition comprising a sufficient amount of urolithin B or a derivative thereof, for increasing muscle cell ...
Fauchet, Fabienne +3 more
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Cancer Medicine, Volume 15, Issue 9, September 2026.ABSTRACT Background Radiotherapy remains a cornerstone of cancer treatment, while its efficacy is often limited by tumor radioresistance and the risk of normal tissue toxicity. Conventional preclinical models, including two‐dimensional (2D) cell cultures and murine xenografts, exhibit significant limitations in recapitulating human tumor ...
Yixian Zhu +4 more
wiley +1 more source
A concise synthesis of glucuronide metabolites of urolithin-B, resveratrol, and hydroxytyrosol
, 2009 7 páginas, 1 figura, 1 tabla, 4 esquemasA simple and direct strategy to chemically synthesize O-β-d-glucuronides of urolithin-B 4, resveratrol 5, and the corresponding hydroxytyrosol derivatives 6, 7 (as a regioisomeric mixture), and 8 is described.
Alcántara, David +6 more
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Microbial method for reproducing the human urolithin metabotypes in vitro and in vivo
, 2022 The present invention relates to a new bacterial strain and a new urolithin named urolithin G. The new strain of the invention is Enterocloster bolteae CEBAS S4A9 DSM 34392 and can customize urolithin production to mimic metabotype A and metabotype B in ...
Beltrán Riquelme, David +4 more
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