Results 71 to 80 of about 4,446 (160)

Understanding extracellular vesicles in antiaging

Periodontology 2000, EarlyView.
Abstract Background Aging is a multifactorial process marked by gradual cellular dysregulation, regulated by hallmarks, including genomic instability, mitochondrial dysregulation, and chronic inflammation. Extracellular vesicles (EVs), especially exosomes, have emerged as pivotal mediators of cell‐to‐cell communication with potential roles in both ...
Paras Ahmad, Nathan E. Estrin, Anton Sculean, Richard J. Miron   +3 more
wiley   +1 more source

The effects of a (poly)phenol‐rich food intervention on markers of exercise‐induced inflammation and oxidative stress: A randomised controlled trial

Experimental Physiology, EarlyView.
Abstract This study examined whether consuming a (poly)phenol‐rich food before strenuous muscle‐damaging exercise can modify post‐exercise markers of inflammation and oxidative stress. Using a double‐blinded, randomised, placebo‐controlled, between‐subjects design, 26 recreationally active males (n = 15) and females (n = 11) consumed higher‐(poly ...
Abrar Al Hebshi, Josh Thorley, Ana Rodriguez‐Mateos, Zicheng Zhang, Lewis J James, Tom Clifford   +5 more
wiley   +1 more source

Urolithin C, a gut metabolite of ellagic acid, induces apoptosis in PC12 cells through a mitochondria-mediated pathway

, 2017
Urolithin C includes apoptosis in PC12 cells through a mitochondria-mediated pathway.
Chao Ma, Yujun Liu, Peipei Yin, Liwei Sun, Linlin Yan, Lingguang Yang, Jianwei Zhang, Lingling Shi   +7 more
core   +1 more source

Metabolomics Insights Into Nutritional Intervention With Polyphenols in Feedlot Beef Cattle

New Zealand Journal of Agricultural Research, Volume 69, Issue 6, December 2026.
Polyphenol‐based feed additives have been increasingly used in feedlot diets due to their potential to modulate rumen fermentation and systemic redox and inflammatory responses; however, mechanistic evidence at the systemic level in finishing cattle remains limited.
Lauro César Ferreira Beltrão, Vinicius Laerte Silva Herreira, Ana Laura dos Santos Munhoz Gôngora, Eduardo Solano Pina dos Santos, Brenda Santos de Oliveira, Alanne Tenório Nunes, Luiz Alberto Colnago, Fernanda Maria Marins Ocampos, Angelica Simone Cravo Pereira, Ana Julia Amaral Hayashida, Marcelo de Queiroz Manella, João Paulo Sigolo Teixeira Bastos, Nara Regina Brandão Cônsolo   +12 more
wiley   +1 more source

Beneficial Role of Natural Polyphenols Against Epilepsy: Greasing the Wheels of Pharmacotherapy Research for Epilepsy

Food Frontiers, Volume 7, Issue 6, November 2026.
ABSTRACT Epilepsy is the most disabling neurological disease that affects all economic classes, age groups, regions, and races. Although many antiseizure drugs are approved for epilepsy treatment, they fail to work in about 30%–40% of patients. Thus, there is a great need to identify better pharmacological agents to treat epilepsy.
Janakiraman Pillai Udaiyappan, Rengasamy Balakrishnan, Manivasagam Muthukumaran Tamilarasan, Subasri Pandian   +3 more
wiley   +1 more source

Investigating the Cytotoxic Effect of Urolithin B and Cerium Oxide Nanoparticles Synthesized from Aloe Vera Plant on Brain Cancer Cell Colony (U87MG) [PDF]

, 2023
Background: Brain cancer is one of the types of cancer that appears with the growth of cancer cells in the brain. In this experimental study, we investigated and compared the effect of cerium oxide nanoparticles synthesized by the green method from Aloe ...
Ghasem Rahimi kalateh shah mohammad, Rahele Zhiani, Majid Darrudi, Alireza Motavalizadeh kakhky, Jamshid Mehrzad   +4 more
core  

Programming Gut Microbiome Function Through Cross‐Feeding: From Ecological Mechanisms to Live Biotherapeutics

Advanced Science, Volume 13, Issue 55, 5 October 2026.
This graphical abstract presents gut microbial cross‐feeding through a Mechanism–Technology–Application framework. It summarizes major resource‐transfer modes, the experimental and computational tools used to establish causality, and potential interventions involving dietary substrates, live biotherapeutic products, and engineered microbes.
Chuankai Sun, Teng Ma, Hao Jin, Zelong Li, Yi Cheng, Jingjin Li, Lai‐Yu Kwok, Zhihong Sun   +7 more
wiley   +1 more source

Postbiotics Unveiled: The Next Emerging Trend in Functional Foods

Food Science &Nutrition, Volume 14, Issue 10, October 2026.
The graphical abstract shows different postbiotic production techniques, such as sonication, fermentation, heat inactivation, high‐pressure processing, dehydration, pH modification, and omic technologies. Additionally, it highlights the emerging health benefits and applications of postbiotics, including immune modulation, gut–brain axis regulation ...
Zoha Wahid, Abdul Momin Rizwan Ahmad, Farheen Zulfiqar, Syed Hassan Bin Usman Shah, Nilab Mohammadi   +4 more
wiley   +1 more source

Preclinical Evaluation of Oral Urolithin-A for the Treatment of Acute Campylobacteriosis in Campylobacter jejuni Infected Microbiota-Depleted IL-10−/− Mice [PDF]

, 2020
Human campylobacteriosis represents an infectious enteritis syndrome caused by Campylobacter species, mostly Campylobacter jejuni. Given that C. jejuni infections are rising worldwide and antibiotic treatment is usually not indicated, novel treatment ...
Mousavi, Soraya, Bereswill, Stefan, Heimesaat, Markus M., Weschka, Dennis   +3 more
core   +1 more source

Microbiome‐Derived Tryptophan Metabolites Regulate AhR Signaling to Restore Epithelial Barrier Integrity in Inflammatory Bowel Disease

MicrobiologyOpen, Volume 15, Issue 5, October 2026.
The graphical abstract illustrates how microbiome‐derived indoles activate the aryl hydrocarbon receptor to restore the intestinal barrier. The picture contrasts the “leaky gut” state with the restored homeostasis achieved through AMPK, Nrf2, and IL‐22 signaling.
Mohammad Ali Mahdiabadi, Asma Moghaddam, Nafiseh Erfanian   +2 more
wiley   +1 more source