Results 21 to 30 of about 5,657 (242)

Urolithin M5 from the Leaves of Canarium album (Lour.) DC. Inhibits Influenza Virus by Targeting Neuraminidase

Molecules, 2022
Ganlanye (GLY), the leaf of Canarium album (Lour.) DC., is a traditional Chinese medicinal herb for warm disease treatment. We found that its aqueous extract could inhibit the influenza A virus.
Mengjie Xiao, Fei Cao, Tao Huang, Yun-Sang Tang, Xin Zhao, Pang-Chui Shaw   +5 more
doaj   +2 more sources

Urolithin A Exerts Neuroprotective Effects Against Ischemic Stroke by Inhibiting Oxidative Stress and Neuroinflammation. [PDF]

CNS Neurosci Ther
Urolithin A (UA) treatment enhances the Nrf2/HO‐1‐mediated antioxidant capacity against ischemic injury postischemic stroke, while also effectively suppressing neuroinflammatory responses. Both of these regulatory effects are likely associated with the NF‐κB signaling pathway, which in turn inhibits neuronal apoptosis and contributes to the improvement
Shao Y, Feng L, Li Y, Cai Y, Yuan H, Tang Q, Yang M, Yang W, Shi H, Mao L.   +9 more
europepmc   +2 more sources

Insights Into the Mechanisms of Biological Aging That Guide Translational and Clinical Research. [PDF]

Aging Med (Milton)
Cellular NAD+ levels can be augmented through supplementation with precursors such as nicotinamide (NAM), nicotinamide riboside (NR), and nicotinamide mononucleotide (NMN). Accumulating preclinical and clinical evidence suggests that NAD+ repletion attenuates both pathological (premature or accelerated) and chronological aging, thereby extending ...
Fang EF, Nilsen H, Scheibye-Knudsen M, Bohr VA, Kang L.   +4 more
europepmc   +2 more sources

Potential impact of urolithin A on pathways relevant to sleep health: a mini review [PDF]

Frontiers in Nutrition
Sleep is vital to human health, and poor sleep health has been associated with numerous chronic conditions, including cardiovascular disease, obesity, depression, and type 2 diabetes. Recently, an emerging area of research has focused on the relationship
Ana Clara da C. Pinaffi-Langley, Faris M. Zuraikat, Faris M. Zuraikat, Marie-Pierre St-Onge, Andriy Yabluchanskiy   +4 more
doaj   +2 more sources

Urolithin-C Suppresses Inflammation by Blocking NF-κB Signaling Pathway in LPS-Induced RAW 264.7 Macrophages

Journal of Inflammation Research
Vani Karadi Manjappa,1,2,* Manjula Mavathuru Venkatappa,3,* Deepadarshan Urs,4 Suliphuldevara Mathada Basavarajaiah,5 Shivakumar Venkataramaiah,3 Sanjana Bai Shivramsingh Mahendranathsingh,1 Sushma Mohan,1 Hunase Rajaiah Pushpavathi,4 ...
Manjappa VK, Venkatappa MM, Urs D, Basavarajaiah SM, Venkataramaiah S, Mahendranathsingh SBS, Mohan S, Pushpavathi HR, Krishnappa DK, Sannaningaiah D   +9 more
doaj   +1 more source

Urolithin-A attenuates neurotoxoplasmosis and alters innate response towards predator odor

Brain, Behavior, & Immunity - Health, 2020
Neurotoxoplasmosis, also known as cerebral toxoplasmosis, is an opportunistic chronic infection caused by the persistence of parasite Toxoplasma gondii cysts in the brain.
Sijie Tan, Wen Han Tong, Ajai Vyas
doaj   +2 more sources

Targeting aging with urolithin A in humans: A systematic review.

Ageing Research Reviews
Urolithin A (UA) is a gut metabolite derived from ellagic acid. This systematic review assesses the potential geroprotective effect of UA in humans. In five studies including 250 healthy individuals, UA (10 - 1000mg/day) for a duration ranging from 28 ...
A. H. Kuerec, Xuan K. Lim, Anderson Khoo, E. Sandalova, L. Guan, Lei Feng, A. Maier   +6 more
semanticscholar   +4 more sources

Individual polyphenol metabotypes and longevity: microbial biotransformation and personalized nutrition interventions [PDF]

Frontiers in Nutrition
Gözde Çalışkan Akımal, Özlem Baran, Meryem Saban Güler, Beraat Dener, Bence Raposa, Duygu Aǧagündüz   +5 more
doaj   +2 more sources

The Metabolite Urolithin-A Ameliorates Oxidative Stress in Neuro-2a Cells, Becoming a Potential Neuroprotective Agent [PDF]

Antioxidants, 2020
Urolithin A is a metabolite generated from ellagic acid and ellagitannins by the intestinal microbiota after consumption of fruits such as pomegranates or strawberries.
Guillermo Cásedas, Francisco Les, Carmen Choya-Foces, Martín Hugo, Víctor López   +4 more
doaj   +2 more sources

UROLITHIN B FOR MUSCLE GROWTH

, 2014
A composition comprising a sufficient amount of urolithin B or a derivative thereof, for increasing muscle cell ...
PRIEM FABIAN, RODRIGUEZ JULIE, FRANCAUX MARC, FAUCHET FABIENNE   +3 more
openaire   +2 more sources