Results 31 to 40 of about 5,657 (242)

Urolithins and intestinal health

open access: yesDrug Discoveries & Therapeutics, 2022
There are trillions of microorganisms in the human intestine. They can react to the intestinal microenvironment by metabolizing food or producing small molecular compounds to affect the host's digestive ability and resist the risk of infection and autoimmune diseases.
Lu, Chunhua   +4 more
openaire   +2 more sources

Separation of Isomeric Forms of Urolithin Glucuronides Using Supercritical Fluid Chromatography [PDF]

open access: yes, 2023
Urolithins are gut microbiota metabolites produced in humans after consuming foods containing ellagitannins and ellagic acid. Three urolithin metabotypes have been reported for different individuals depending on the final urolithins produced.
José Bernal   +25 more
core   +1 more source

Correlation between intestinal microbiota and urolithin metabolism in a human walnut dietary intervention

open access: yesBMC Microbiology
This study is to investigate the relationship between the intestinal microbiota and urine levels of the ellagic acid-derived polyphenols, the urolithins, in a cohort of subjects following a three-week walnut dietary intervention.
Huijia Liu   +7 more
doaj   +2 more sources

Differential Role of Active Compounds in Mitophagy and Related Neurodegenerative Diseases

open access: yesToxins, 2023
Neurodegenerative diseases, such as Alzheimer’s disease or Parkinson’s disease, significantly reduce the quality of life of patients and eventually result in complete maladjustment. Disruption of the synapses leads to a deterioration in the communication
Mark Makarov, Eduard Korkotian
doaj   +1 more source

Ellagic acid and its fermentative derivative urolithin A show reverse effects on the gp91-phox gene expression, resulting in opposite alterations in all-trans retinoic acid-induced superoxide generating activity of U937 cells

open access: yesBiochemistry and Biophysics Reports, 2021
Ellagitannins (esters composed of glucose and ellagic acid) are hydrolyzed to generate ellagic acid in gut followed by conversion of ellagic acid to urolithins such as urolithin A by intestinal bacteria.
Hidehiko Kikuchi   +3 more
doaj   +1 more source

In vivo anti-inflammatory and antioxidant properties of ellagitannin metabolite urolithin A [PDF]

open access: yes, 2011
Urolithin A is a major metabolite produced by rats and humans after consumption of pomegranate juice or pure ellagitannin geraniin. In this study, we investigated the anti-inflammatory effect of urolithin A on carrageenan-induced paw edema in mice.
Tai, Akihiro   +6 more
core   +2 more sources

Pomegranate Juice Ameliorates Dopamine Release and Behavioral Deficits in a Rat Model of Parkinson’s Disease

open access: yesBrain Sciences, 2021
Pomegranate juice (PJ) is a rich source of ellagitannins (ETs), precursors of colonic metabolite urolithin A, which are believed to contribute to pomegranate’s neuroprotective effect.
Małgorzata Kujawska   +8 more
doaj   +1 more source

Sarcopenia and Muscle Aging: A Brief Overview [PDF]

open access: yesEndocrinology and Metabolism, 2020
The world is facing the new challenges of an aging population, and understanding the process of aging has therefore become one of the most important global concerns.
Tam Dao   +8 more
doaj   +1 more source

Isolation of Human Intestinal Bacteria Capable of Producing the Bioactive Metabolite Isourolithin A from Ellagic Acid

open access: yesFrontiers in Microbiology, 2017
Urolithins are intestinal microbial metabolites produced from ellagitannin- and ellagic acid-containing foods such as walnuts, strawberries, and pomegranates.
María V. Selma   +7 more
doaj   +1 more source

Constituents and Metabolites of a French Oak Wood Extract (Robuvit®) in Serum and Blood Cell Samples of Women Undergoing Hysterectomy

open access: yesFrontiers in Pharmacology, 2020
Ellagitannins are signature constituents of oak wood and their consumption has been associated with various health benefits. In vivo, they undergo metabolic degradation including gut microbial metabolism yielding urolithins.
Linda Volpp   +5 more
doaj   +1 more source

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