Results 111 to 120 of about 21,131,763 (241)

Patient empowerment and the Mediterranean diet as a possible tool to tackle prediabetes associated with overweight or obesity: a pilot study [PDF]

, 2019
AIM: The objective of this study was to investigate the effect of implementation of short-term patient empowerment as applied to Mediterranean diet (MD) adherence on metabolic and anthropometric parameters in prediabetic overweight or obese subjects.
Altieri, B., Barrea, L., Colao, A., Di Somma, C., Muscogiuri, G., Orio, F., Savastano, S., Spinosa, T., Vecchiarini, M.   +8 more
core   +1 more source

Mitochondria‐associated membranes (MAMs): molecular organization, cellular functions, and their role in health and disease

FEBS Open Bio, Volume 16, Issue 1, Page 11-24, January 2026.
Mitochondria‐associated membranes (MAMs) are contact sites between the endoplasmic reticulum and mitochondria that regulate calcium signaling, lipid metabolism, autophagy, and stress responses. This review outlines their molecular organization, roles in cellular homeostasis, and how dysfunction drives neurodegeneration, metabolic disease, cancer, and ...
Viet Bui, Maryline Santerre, Natalia Shcherbik, Bassel E Sawaya   +3 more
wiley   +1 more source

Promoting Drp1-mediated mitochondrial fission in midlife prolongs healthy lifespan of Drosophila melanogaster [PDF]

, 2017
The accumulation of dysfunctional mitochondria has been implicated in aging, but a deeper understanding of mitochondrial dynamics and mitophagy during aging is missing.
A Rana, A Tanaka, AC Poole, AC Poole, AM Pickrell, AS Rambold, B DuBoff, C Lopez-Otin, CC Yang, CQ Scheckhuber, D Mathur, D Ryu, DC Chan, DC David, DC Rubinsztein, DJ Klionsky, DP Narendra, DR Green, DW Walker, E Beregi, E Dambroise, E Lionaki, E Owusu-Ansah, E Smirnova, E Ziviani, ES Vincow, F Demontis, G Ashrafi, G Twig, G Twig, GD Cartee, H Abeliovich, H Deng, H Nakatogawa, I Pimenta de Castro, IP Castro de, J Durieux, J Park, J Yun, JM Copeland, JP Leduc-Gaudet, K Kavanagh, K Mao, K Palikaras, L Buhlman, L Partridge, L Poirier, M Frank, M Kaeberlein, M Manczak, M Rera, M Rera, M Schrader, MJ Drummond, N Sun, N Sun, N Thevaranjan, NC Chan, P Reis-Rodrigues, R Coleman, R Kandimalla, RH Houtkooper, RJ Youle, RJ Youle, S Geisler, S Gelino, S Hoppins, S Iqbal, SE Wohlgemuth, WW Ja, X Wang, Y Wang, Y Yang   +72 more
core   +6 more sources

Differential Effects of Whole Red Raspberry Polyphenols and Their Gut Metabolite Urolithin A on Neuroinflammation in BV-2 Microglia [PDF]

, 2020
Whole red raspberry polyphenols (RRW), including ellagic acid, and their gut-derived metabolite, urolithin A (UroA), attenuate inflammation and confer health benefits.
Albusharif, Mahaa, Chaidez, Virginia, Chung, Soonkyu, Polenz, Luke, Ramer-Tait, Amanda E., Schlange, Stacie, Toney, Ashley Mulcahy, Works, Duncan   +7 more
core   +5 more sources

Emerging Therapeutic Strategies in Anti‐Aging Medicine: A Comprehensive Review

Medicine Bulletin, Volume 2, Issue 1, Page 94-123, January 2026.
ABSTRACT Aging is orchestrated by interconnected hallmarks such as genomic instability, mitochondrial dysfunction, cellular senescence, and disrupted intercellular communication, which collectively drive chronic disease progression. Recent advances have expanded therapeutic opportunities to include pharmacological agents, gene and epigenome editing ...
Yundong Peng, Rui Li, Huan Li, Jun Zhou, Xuanshi Liu, Guilherme Valente, Tatiana de Campos Melo, Sifan Chen, Lei Gu   +8 more
wiley   +1 more source

Fermentation of Green Tea Extract by Streptococcus thermophilus FUA329 and Evaluation of Storage Characteristics

Shipin gongye ke-ji
In order to evaluate the effect of Streptococcus thermophilus fermentation on green tea extract and its storage characteristics, this study used Streptococcus thermophilus FUA329 and S.
Shuting HAN, Ziyan HUA, Yaowei FANG, Guang YANG, Xiaoyue HOU, Wenmei ZHOU, Ming TANG, Shu LIU   +7 more
doaj   +1 more source

Effects of pomegranate juice in circulating parameters, cytokines, and oxidative stress markers in endurance-based athletes: A randomized controlled trial [PDF]

, 2016
Objective: The aim of the present study was to assess the effects of pomegranate juice on the level of oxidative stress in the blood of endurance-based athletes.
Funes, Lorena, Fuster-Muñoz, Encarnación, Martínez-Peinado, Pascual, Roche, Enrique, Sempere Ortells, José Miguel, Vicente Salar, Nestor   +5 more
core   +2 more sources

An Integrated Engineering Approach to Creating Health‐Modulating Postbiotics

Molecular Nutrition &Food Research, Volume 70, Issue 1, January 2026.
Postbiotics have emerged as a promising alternative to live probiotics, offering comparable health benefits while overcoming challenges related to safety, stability, and shelf life. The review addresses current challenges in standardizing postbiotic definitions and production processes, and by outlining future research directions necessary to unlock ...
Michael Leonidas Chikindas, Diana E. Roopchand, Santosh Kumar Tiwari, Liubov S. Sichel, Mukund V. Karwe, Nitin Nitin, Vitor Luis Fagundes, Igor V. Popov, John R. Tagg, Xuanxuan Lu, Svetoslav Dimitrov Todorov   +10 more
wiley   +1 more source

Can Urolithin A Help in Curing COVID-19 Infection?

Qeios, 2023
Urolithin A (UA) is a natural gut microbiome-derived food metabolite that is synthesized after eating certain foods high in polyphenols. UA offers significant health benefits for our body, especially its antioxidant and anti-inflammatory roles, which lead us to wonder if UA can participate directly or indirectly in curing or, at the very least ...
openaire   +1 more source

TRANSLATING UROLITHIN A BENEFITS ON MUSCLE MITOCHONDRIA TO HUMANS [PDF]

Innovation in Aging, 2018
Urolithin A (UA) is a natural metabolite produced by the gut microflora upon ingestion of ellagitanins, a class of molecules that is abundant in pomegranates, nuts and berries. We have published a study demonstrating that UA induces mitophagy in vivo following oral consumption in worms and in rodents (Ryu et al., Nat Med 2016).
A Singh, P Andreux, W Blanco-Bose, P Aebischer, J Auwerx, C Rinsch   +5 more
openaire   +1 more source