Results 121 to 130 of about 21,131,763 (241)

Urolithin A alleviates schizophrenic-like behaviors and cognitive impairment in rats through modulation of neuroinflammation, neurogenesis, and synaptic plasticity

Scientific Reports
Cognitive impairment in schizophrenia occurs in the early stages of the disease and is closely associated with prognosis. Alleviation of cognitive impairment in schizophrenia faces major challenges owing to the lack of preventive and therapeutic drugs ...
Zhengyuan Huang, Zhongyu Ren, Sanwang Wang, Ling Xiao, Yipeng Ling, Yinping Xie, Gaohua Wang, Benhong Zhou   +7 more
semanticscholar   +1 more source

Optimization of Medium and Transcriptomic Analysis for Converting Ellagic Acid to Urolithin A by Limosilactobacillus fermentum FUA033

Shipin gongye ke-ji
This study aimed to establish a systematic framework for enhancing the bioconversion efficiency of ellagic acid to urolithin A by Limosilactobacillus fermentum FUA033 through rational medium engineering, while deciphering the molecular orchestration ...
Gewen ZHANG, Liangliang QIAN, Wenmei ZHOU, Yanyan GONG, Tao CHEN, Yingling LIU, Yaowei FANG, Shu LIU   +7 more
doaj   +1 more source

In vivo administration of urolithin A and B prevents the occurrence of cardiac dysfunction in streptozotocin-induced diabetic rats

Cardiovascular Diabetology, 2017
Background Emerging evidence suggests that specific (poly)phenols may constitute new preventative strategies to counteract cell oxidative stress and myocardial tissue inflammation, which have a key role in the patho-physiology of diabetic cardiomyopathy.
Monia Savi, Leonardo Bocchi, Pedro Mena, Margherita Dall’Asta, Alan Crozier, Furio Brighenti, Donatella Stilli, Daniele Del Rio   +7 more
doaj   +1 more source

Amyloid Beta in Alzheimer's Disease: Mechanisms, Biomarker Potential, and Therapeutic Targets

CNS Neuroscience &Therapeutics, Volume 31, Issue 12, December 2025.
The limited clinical efficacy of anti‐Aβ antibodies has challenged the Aβ hypothesis, compelling the integration of key mechanisms—including neuroinflammation, mitochondrial dysfunction, oxidative stress, and post‐translational modifications of Aβ—into a revised model of Alzheimer's disease.
Shamseddin Ahmadi, Shiler Khaledi, Kimia Ahmadi, Kambiz Hassanzadeh   +3 more
wiley   +1 more source

Modulatory Effects of Bifidobacterium longum Subsp. Longum BL21 on Intestinal Barrier Impairment and Metabolic Dysregulation in a Low‐Dose Dextran Sulfate Sodium‐Induced Chronic Inflammation Model

Food Bioengineering, Volume 4, Issue 4, Page 447-461, December 2025.
Abstract Chronic low‐grade intestinal inflammation is closely linked to gut barrier dysfunction and metabolic disturbance. This study established a low‐dose dextran sulfate sodium (DSS)‐induced chronic inflammation model and evaluated the protective effects of Bifidobacterium longum subsp.
Yue Huang, Yukun Sun, Yao Dong, Zhonghui Gai, Xia Gong, Qing Xia, Mei Han   +6 more
wiley   +1 more source

Pomegranate (Punica granatum L.): A medicinal plant with myriad biological properties - A short review [PDF]

, 2010
The pomegranate, Punica granatum L., which can be found throughout the Mediterranean region, in Southeast Asia, California and Arizona in USA was in ancient times referred as possessing powers of fertility, abundance and good luck (fruit). The biological
Antunes, Maria Dulce, Miguel, Maria Graça, Neves, M. A.   +2 more
core  

Alcohol‐Related Liver Disease and Metabolic Dysfunction‐Associated Steatotic Liver Disease: Molecular Pathogenesis and Therapeutic Interventions

MedComm, Volume 6, Issue 12, December 2025.
Alcohol‐related (ALD) and metabolic dysfunction‐associated (MASLD) steatotic liver disease, while initiated by distinct etiologies (ethanol vs. metabolic stress), converge on shared core pathogenic pathways that drive progression. These include dysregulated lipid metabolism, programmed cell death, cellular senescence, gut dysbiosis, and immune ...
Yupin Tan, Yirui Hu, Ye Yang, Huikuan Chu   +3 more
wiley   +1 more source

Randomised controlled pilot study to assess the feasibility of a Mediterranean Portfolio dietary intervention for cardiovascular risk reduction in HIV dyslipidaemia:A study protocol [PDF]

, 2016
Introduction: HIV drug treatment has greatly improved life expectancy, but increased risk of cardiovascular disease remains, potentially due to the additional burdens of infection, inflammation and antiretroviral treatment.
Frost, Gary, Garcia-Perez, Isabel, Hemming, Karla, Redwood, Sabi, Stradling, Clare, Taheri, Shahrad, Thomas, G. Neil   +6 more
core   +4 more sources

Potential of Urolithin A to improve joint health

Aging, 2023
D’Amico, Davide, Lotz, Martin
openaire   +2 more sources

Anti-inflammatory activity of Punica granatum L. (Pomegranate) rind extracts applied topically to ex vivo skin [PDF]

, 2016
Coadministered pomegranate rind extract (PRE) and zinc (II) produces a potent virucidal activity against Herpes simplex virus (HSV); however, HSV infections are also associated with localised inflammation and pain.
Bugert, Joachim, Denyer, Stephen P., Heard, Charles M., Houston, David   +3 more
core   +1 more source