Results 111 to 120 of about 2,467 (216)
Hydrolysable tannin-based diet rich in gallotannins has a minimal impact on pig performance but significantly reduces salivary and bulbo-urethral gland size [PDF]
Tannins have long been considered ‘anti-nutritional’ factors in monogastric nutrition, shown to reduce feed intake and palatability. However, recent studies revealed that compared to condensed tannins, hydrolysable tannins (HT) appear to have far less ...
Ampuero-Kragten, S. +7 more
core +1 more source
This study reveals that Urolithin A (UA) counteracts alcohol‐induced cognitive and social dysfunction (AICSD) via a gut microbiome‐dependent mechanism. UA‐enriched Bacteroids sartorii and Parabacteroids distasonis elevate anandamide (AEA), which activates the CB1R‐DRD2‐Rap1 signaling cascade to drive synaptic repair and reduce neuroinflammation ...
Hongbo Zhang +9 more
wiley +1 more source
The glycosyltransferase GALNT10 facilitates ovarian cancer metastasis through the induction of tumor cell EMT and tumor vascular dysfunction. GALNT10 enhanced the extracellular secretion of IGFBP7 through O‐GalNAc glycosylation modification at the T188 site, which subsequently interacts with CD93 on endothelial cells, leading to vascular remodeling ...
Yanan Zhang +9 more
wiley +1 more source
Gut microbiota modulation of chemotherapy efficacy and toxicity [PDF]
Evidence is growing that the gut microbiota modulates the host response to chemotherapeutic drugs, with three main clinical outcomes: facilitation of drug efficacy; abrogation and compromise of anticancer effects; and mediation of toxicity.
Alexander, James L. +5 more
core +1 more source
ABSTRACT The rising incidence of chronic diseases globally has drawn widespread attention to phytochemicals, which exert targeted preventive and alleviating effect by modulating gut microbiota; thus, a potential strategy for precision nutritional interventions is offered.
Shiqi Bai +6 more
wiley +1 more source
Multiclass methods in the analysis of metabolomic datasets: the example of raspberry cultivar volatile compounds detected by GC-MS and PTR-MS [PDF]
Multiclass sample classification and marker selection are cutting-edge problems in metabolomics. In the present study we address the classification of 14 raspberry cultivars having different levels of gray mold (Botrytis cinerea) susceptibility.
Aprea, Eugenio +5 more
core +1 more source
Mitochondria and the Actin Cytoskeleton in Neurodegeneration
ABSTRACT Mitochondrial dysfunction and cytoskeletal disorganization are widely recognized hallmarks of neurodegenerative diseases such as Alzheimer's disease (AD), Parkinson's disease (PD), Huntington's disease (HD), and amyotrophic lateral sclerosis (ALS).
Shivani Tuli +3 more
wiley +1 more source
The maternal-infant transmission of several urolithins through breast milk and the gut colonization of infants by the urolithin-producing bacterium Gordonibacter during their first year of life were explored. Two trials (proof-of-concept study: n = 11; validation study: n = 30) were conducted, where breastfeeding mothers consumed walnuts as a dietary ...
Cortés-Martín, Adrian +8 more
openaire +4 more sources
Bioavailable constituents/metabolites of pomegranate ( L) preferentially inhibit COX2 activity and IL-1beta-induced PGE production in human chondrocytes [PDF]
Several recent studies have documented that supplementation with pomegranate fruit extract inhibits inflammatory symptoms in vivo. However, the molecular basis of the observed effects has not been fully revealed. Although previous studies have documented
Meenakshi Shukla +4 more
core +1 more source
Potential of Urolithin A to improve joint health
D’Amico, Davide, Lotz, Martin
openaire +2 more sources

