Results 31 to 40 of about 23,614 (207)
Frontiers in Physiology, 2022 Prior studies suggest that urothelium-released adenosine 5′-triphosphate (ATP) has a prominent role in bladder mechanotransduction. Urothelial ATP regulates the micturition cycle through activation of purinergic receptors that are expressed in many cell ...
Mafalda S. L. Aresta Branco +4 more
doaj +1 more source
Fibroblast growth factor receptor 3 activation plays a causative role in urothelial cancer pathogenesis in cooperation with Pten loss in mice [PDF]
, 2014 Although somatic mutations and overexpression of the tyrosine kinase fibroblast growth factor receptor 3 (FGFR3) are strongly associated with bladder cancer, evidence for their functional involvement in the pathogenesis remains elusive.
Ahmad +48 more
core +1 more source
Free ureteral replacement in rats: regeneration of ureteral wall components in the acellular matrix graft. [PDF]
, 1997 ObjectivesTo evaluate ureteral replacement by a free homologous graft of acellular matrix in a rat model.MethodsIn 30 male Sprague-Dawley rats, a 0.3 to 0.8-cm midsegment of the left ureter was resected and replaced with an acellular matrix graft of ...
Dahiya, R +5 more
core +1 more source
European Journal of Histochemistry, 2020 Lectin histochemistry (LHC) and immunohistochemistry (IHC), which demonstrate the composition and localisation of sugar residues and proteins in cell membranes, respectively, are generally used separately.
Daša Zupančič +3 more
doaj +1 more source
TRPA1 channel mediates methylglyoxal-induced mouse bladder dysfunction
Frontiers in Physiology, 2023 Introduction: The transient receptor potential ankyrin 1 channel (TRPA1) is expressed in urothelial cells and bladder nerve endings. Hyperglycemia in diabetic individuals induces accumulation of the highly reactive dicarbonyl compound methylglyoxal (MGO),
Akila L. Oliveira +6 more
doaj +1 more source
Frontiers in Immunology, 2019 Inherited Primary Immunodeficiency (PID) disorders are associated with increased risk of malignancy that may relate to impaired antitumor immune responses or a direct role for PID germline mutations in tumorigenesis.
Vanessa Daza-Cajigal +16 more
doaj +1 more source
Indian Journal of Pathology and Microbiology, 2023 Mixed epithelial and stromal tumor of the kidney (MESTK) occurs almost exclusively in perimenopausal women while rarely in children. Only five pediatric patients have been described previously. Herein, we report a girl and a boy with MESTK, aged 3- and 4-
Xia Wei +3 more
doaj +1 more source
Purinergic receptor mediated calcium signalling in urothelial cells [PDF]
, 2019 Non-neuronal ATP released from the urothelium in response to bladder stretch is a key modulator of bladder mechanosensation. Whilst non-neuronal ATP acts on the underlying bladder afferent nerves to facilitate sensation, there is also the potential for ...
Brierley, Stuart M +4 more
core +3 more sources
TUMORS OF THE UPPER UROTHELIUM [PDF]
American Journal of Roentgenology, 1975 Forty-two cases of malignant tumors of renal pelvis were reviewed: 28 were transitional cell carcinomas; and 14 were squamous cell carcinomas.The natural history and spread of the disease is discussed in detail. Transitional cell carcinomas spread primarily to the ureter (40 per cent), followed closely by the renal bed (33 per cent) and bladder (30 per
openaire +2 more sources
Invasive Bladder Cancer With Peritoneal Invasion and Rectal Involvement Causing Rectal, Bilateral Ureteral, and Common Bile Duct Obstruction Without a Retroperitoneal Mass: A Case Report. [PDF]
IJU Case RepABSTRACT Introduction Bladder cancer (BC) is rarely associated with common bile duct (CBD) obstruction. We report a case of BC with peritoneal invasion and rectal involvement complicated by bilateral ureteral and biliary obstruction. Case Presentation A 77‐year‐old man presented with abdominal pain.
Imai K +6 more
europepmc +2 more sources