Prospective study to compare antibiosis versus the association of N-acetylcysteine, D-mannose and morinda citrifolia fruit extract in preventing urinary tract infections in patients submitted to urodynamic investigation [PDF]
, 2017 BACKGROUND: The abuse of antimicrobical drugs has increased the resistance of microorganisms to treatments, thus to make urinary tract infections (UTIs) more difficult to eradicate.
Al Rawashdah, S +12 more
core +2 more sources
Update on cellular expression and function of ANO1 channels in urethral smooth muscle
The Journal of Physiology, EarlyView.Abstract figure legend Activation of ANO1 channels and resulting Cl− efflux are suggested to modulate urethral smooth muscle contractility by enhancing Ca2+ influx via voltage‐dependent Ca2+ entry and resulting contraction in urethral smooth muscle cells.
Bernard T. Drumm, Neha Gupta
wiley +1 more source
Utility of a dual immunostain cocktail comprising of p53 and CK20 to aid in the diagnosis of non-neoplastic and neoplastic bladder biopsies [PDF]
, 2009 Background Distinction between non-neoplastic and neoplastic bladder lesions is therapeutically and prognostically important. Our objective is to describe the use of double immunohistochemistry (DIHC) for p53+CK20 as a tool for diagnosing neoplasia in ...
Isil Z Yildiz +5 more
core +2 more sources
The FASEB Journal, Volume 40, Issue 7, 15 April 2026.Abnormal extracellular ATP levels cause lower urinary tract symptoms (LUTS). Here, we demonstrate that overexpression of ENTPD1 (CD39TG)—an ATP/ADP converting enzyme—reduces voiding frequency while increasing void volume. Conversely, ENTPD1 deficiency results in frequent, small‐volume voiding.
Zhaobo Luo +7 more
wiley +1 more source
A study of cytokeratin 20 immunostaining in the urothelium of neuropathic bladder of patients with spinal cord injury [PDF]
, 2002 Background Normal urothelium is characterised by terminally differentiated superficial cells, which express cytokeratin 20 in the cytoplasm. In contrast, cultured human stratified urothelium, which does not undergo complete terminal differentiation of ...
Soni Bakul M +6 more
core +1 more source
The Botulinum Treatment of Neurogenic Detrusor Overactivity: The Double-Face of the Neurotoxin
Toxins, 2019 Botulinum neurotoxin (BoNT) can counteract the highly frequent involuntary muscle contractions and the uncontrolled micturition events that characterize the neurogenic detrusor overactivity (NDO) due to supra-sacral spinal cord lesions.
Chiara Traini, Maria Giuliana Vannucchi
doaj +1 more source
Shed urinary ALCAM is an independent prognostic biomarker of three-year overall survival after cystectomy in patients with bladder cancer. [PDF]
, 2016 Proteins involved in tumor cell migration can potentially serve as markers of invasive disease. Activated Leukocyte Cell Adhesion Molecule (ALCAM) promotes adhesion, while shedding of its extracellular domain is associated with migration. We hypothesized
Arnold Egloff, Shanna A +14 more
core +2 more sources
Advanced Science, Volume 13, Issue 18, 27 March 2026.This study presents an intravesical delivery strategy of ferroptosis‐ and immunity‐inducing nanozyme‐loaded thermoresponsive hydrogels (FMCC@PNH) for enhanced bladder cancer therapy. Abstract Current intravesical therapies for bladder cancer after resection are limited by poor tissue penetration, off‐target effects, and insufficient efficacy.
Yongnan Jiang +11 more
wiley +1 more source
Immunocytochemical characterisation of cultures of human bladder mucosal cells [PDF]
, 2011 Background The functional role of the bladder urothelium has been the focus of much recent research. The bladder mucosa contains two significant cell types: urothelial cells that line the bladder lumen and suburothelial interstitial cells or ...
Jacqueline R Woodman +5 more
core +2 more sources
Food Science &Nutrition, Volume 14, Issue 3, March 2026.Higher dietary ketogenic ratio was associated with lower prevalence of overactive bladder, partially mediated by dietary inflammation and central adiposity in U.S. adults (NHANES 2009–2018). ABSTRACT Overactive bladder (OAB) is characterized by urinary urgency, often accompanied by increased frequency and nocturia, and is associated with impaired ...
Xuefeng Jin +12 more
wiley +1 more source