Results 101 to 110 of about 5,130,717 (259)

Effect of Ursodeoxycholic Acid on the Biodistribution and Excretion of Technetium-99m Radiopharmaceuticals in Rat: A Potential Image Quality Enhancer

, 2021
Yeon‐Hee Han, Hwan‐Jeong Jeong, Eun‐Mi Kim, Fatima Boud, Seok Tae Lim, Sun Young Lee, Myung‐Hee Sohn   +6 more
openalex   +1 more source

Ursodeoxycholic acid induces sarcopenia associated with decreased protein synthesis and autophagic flux [PDF]

, 2023
Josué Orozco-Aguilar, Franco Tacchi, Francisco Aguirre, Mayalen Valero‐Breton, Mauricio Castro‐Sepúlveda, Felipe Simón, Claudio Cabello‐Verrugio   +6 more
openalex   +1 more source

Efficacy, Safety and Tolerability of Volixibat, an IBAT Inhibitor, in Patients With Intrahepatic Cholestasis of Pregnancy

Liver International, Volume 46, Issue 3, March 2026.
ABSTRACT Intrahepatic cholestasis of pregnancy (ICP) presents with cholestatic pruritus, elevated sBA and increased risk of adverse perinatal outcomes. Volixibat is a minimally absorbed IBAT inhibitor that interrupts enterohepatic recirculation. We describe four patients with ICP with pruritus and sBA > ULN treated with volixibat (20 or 80 mg BID ...
Caroline Ovadia, Sophia Stone, Baha Sibai, Tiago Nunes, Douglas B. Mogul, Jayshree Krishnaswami, Jennifer Kahng, Furong Li, Qurratul Ann Warsi, Elaine Chien, Pamela Vig, Catherine Williamson   +11 more
wiley   +1 more source

Prevention of N‐Methylnitrosourea‐induced Colon Tumorigenesis by Ursodeoxycholic Acid in F344 Rats [PDF]

, 1998
Tomio Narisawa, Yoko Fukaura, Kunihiko Terada, Hideaki Sekiguchi   +3 more
openalex   +1 more source

IGFBP4 is a Metric for Primary Biliary Cholangitis and Attenuates Biliary Epithelial Cell Injury

Liver International, Volume 46, Issue 3, March 2026.
ABSTRACT Background and Aims Immune‐mediated bile duct injury is the primary histological feature of autoimmune cholestatic liver diseases. Macrophages, the most abundant immune cell population in the liver, have been postulated to play a critical role in biliary repair. However, it is unclear whether activated macrophages interact with injured biliary
Xing Zhou, Shuyu Shao, Danning Yang, Ziyan Cheng, Toshihiro Tanaka, Patrick S. C. Leung, Koichi Tsuneyama, Aftab A. Ansari, William M. Ridgway, Pietro Invernizzi, Christopher L. Bowlus, M. Eric Gershwin, Weici Zhang   +12 more
wiley   +1 more source

Ursodeoxycholic acid in intrahepatic cholestasis of pregnancy: a systematic review and individual participant data meta-analysis

The Lancet Gastroenterology and Hepatology, 2021
Caroline Ovadia, J. Sajous, Paul Townsend Seed, Kajol Patel, Nicholas J Williamson, G. Attilakos, F. Azzaroli, Y. Bacq, L. Batsry, K. Broom, Romana Brun-Furrer, L. Bull, J. Chambers, Yue Cui, Min Ding, P. Dixon, M. Estiù, F. Gardiner, V. Geenes, M. Grymowicz, B. Günaydın, W. Hague, C. Haslinger, Yayi Hu, U. Indraccolo, A. Juusela, S. Kane, A. Kebapcilar, L. Kebapçılar, K. Kohari, J. Kondrackienė, M. Koster, R. Lee, Xiaohua Liu, A. Locatelli, R. Macías, R. Madazlı, Agata Majewska, K. Maksym, J. Marathe, A. Morton, M. Oudijk, D. Öztekin, M. Peek, A. Shennan, R. Tribe, V. Tripodi, Naciye Türk Özterlemez, T. Vasavan, L. Wong, Y. Yinon, Qianwen Zhang, K. Zloto, H. Marschall, J. Thornton, L. Chappell, C. Williamson   +56 more
semanticscholar   +1 more source

Effect of Ursodeoxycholic Acid Alone Verses Ursodeoxycholic Acid and Rifampicin in Obstetric Cholestasis

Pakistan Journal of Medicine and Dentistry
Background: Intrahepatic cholestasis of pregnancy (ICP) is a common liver disorder in pregnancy, associated with pruritus, elevated bile acids, and increased risk of adverse perinatal outcomes.
Ayesha Amjad, Sadia Aftab, Tahreem Sehar, Samana Haider, Tehmina Aziz Qureshi, Kainaat Kanwal   +5 more
doaj   +1 more source

Comparative effects of cholic, chenodeoxycholic, and ursodeoxycholic acids on micellar solubilization and intestinal absorption of cholesterol

Journal of Lipid Research, 1981
Cholesterol absorption was studied in mice receiving cholic, chenodeoxycholic, or ursodeoxycholic acids (0.2% of the diet) for 2 months. Cholesterol absorption was greater with cholic acid (79%) than with chenodeoxycholic acid feeding (60%) and the ...
M O Reynier, J C Montet, A Gerolami, C Marteau, C Crotte, A M Montet, S Mathieu   +6 more
doaj   +1 more source

Bile Acid Binding Resins Improve Glucagon Receptor Agonist‐Mediated Weight Loss in Diet‐Induced Obese Mice

Obesity, Volume 34, Issue 2, Page 428-438, February 2026.
ABSTRACT Objective Glucagon‐receptor (GCGR) agonism reguglates bile acid (BA) metabolism and promotes weight loss in diet‐induced obese (DIO) mice. Thus, we hypothesized that BA signaling contributes to GCGR‐stimulated weight loss. Methods To test this hypothesis, we utilized BA‐binding resins (BARs; colesevelam [Colsv] and cholestyramine [Cstyr]) to ...
Teayoun Kim, Mackenzie J. Pearson, Huixian Hong, Shelly Nason, Khadija Seck, Jessica Antipenko, Natalie Presedo, Richard DiMarchi, William C. Roell, Kirk Habegger   +9 more
wiley   +1 more source

Nutritional approach in a growing Jack Russell terrier with gall bladder agenesis

Veterinary Record Case Reports, Volume 14, Issue 1, February 2026.
Abstract An asymptomatic male Jack Russell terrier diagnosed at the age of 18 weeks with congenital gall bladder agenesis, confirmed by computed tomography scan, after finding abnormally high values for liver enzymes in a routine blood count. Treatment with liver‐protective agents S‐adenosylmethionine and ursodeoxycholic acid was initiated. At 6 months
Tamara Seghers, Matthias Dennler, Brigitta Wichert, Annette Liesegang   +3 more
wiley   +1 more source