Results 131 to 140 of about 5,130,717 (259)

Altered Serum Bile Acid Pattern as an Independent Factor for Covert and Overt Hepatic Encephalopathy in Patients With Cirrhosis

open access: yesHepatology Research, Volume 56, Issue 1, Page 60-69, January 2026.
ABSTRACT Aim Bile acid (BA) signaling plays an important role in the pathogenesis of hepatic encephalopathy (HE), including covert (CHE) and overt HE (OHE). However, few studies have examined its clinical impact in patients with cirrhosis. Methods This retrospective study included patients with cirrhosis who underwent CHE assessment using a computer ...
Takao Miwa   +8 more
wiley   +1 more source

Ursodeoxycholic Acid Therapy in Pediatric Patients With Progressive Familial Intrahepatic Cholestasis [PDF]

open access: bronze, 1997
E. Jacquemin   +7 more
openalex   +1 more source

New cases of δ‐aminolevulinic acid dehydratase deficiency: Functional insights into gene variants using an innovative mouse liver model

open access: yesJournal of Internal Medicine, Volume 299, Issue 1, Page 126-142, January 2026.
Abstract Background Dysfunction of δ‐aminolevulinic acid dehydratase (ALAD), the second enzyme involved in heme biosynthesis, leads to two pathologies: genetic and acquired. The genetic form is an ultrarare, severe childhood‐onset disease inherited in an autosomal recessive manner, whereas the acquired form usually affects adults due to enzyme ...
Elena Di Pierro   +22 more
wiley   +1 more source

Are Postprandial Bile Acid Levels Helpful in Predicting Perinatal Complications in Patients with Intrahepatic Cholestasis of Pregnancy?

open access: yesÇukurova Üniversitesi Tıp Fakültesi Dergisi, 2015
Purpose: To determine the outcomes of Iintrahepatic cholestasis of pregnancy and the role of postprandial serum bile acid levels in the prediction of perinatal complications.
Kudret Erkenekli   +5 more
doaj  

Medical Management of Polycystic Liver Disease: A Position Statement From the European Reference Network on Hepatological Diseases

open access: yesLiver International, Volume 46, Issue 1, January 2026.
ABSTRACT Polycystic liver disease (PLD) is a rare genetic disorder characterised by progressive liver enlargement due to multiple cysts. The main symptoms are liver volume‐related. Although randomised controlled trials have shown that somatostatin analogues (SSAs) reduce liver volume as well as symptoms, specific guidance on when and how to use SSAs in
Sophia Heinrich   +16 more
wiley   +1 more source

StAR Protein Deficiency in Clinical Practice: A Case Series From Saudi Arabia

open access: yesCase Reports in Endocrinology, Volume 2026, Issue 1, 2026.
Objectives Steroidogenic acute regulatory (StAR) protein deficiency is a rare autosomal recessive disorder that disrupts steroid hormone biosynthesis, resulting in congenital adrenal hyperplasia (CAH) and variations in sexual development. However, limited data is available in Saudi Arabia.
Abeer Alabduljabbar   +6 more
wiley   +1 more source

Mild intrahepatic cholestasis of pregnancy—A call to redefine diagnostic criteria and consider a new management paradigm

open access: yes
Pregnancy, Volume 2, Issue 1, January 2026.
Minhazur Sarker   +9 more
wiley   +1 more source

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