Results 71 to 80 of about 5,130,717 (259)

Vedolizumab for extraintestinal manifestations in pediatric inflammatory bowel disease: Results from the VedoKids study

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Extraintestinal manifestations (EIMs) manifest in 6%‐47% of patients with inflammatory bowel disease (IBD). Here, we characterize the course of EIMs in pediatric patients receiving vedolizumab included in the VedoKids cohort study. This was a subgroup analysis of the pediatric VedoKids cohort, a multicenter, prospective study of children (aged
Giulia D'Arcangelo, Dan Turner, Oren Ledder, Esther Orlanski‐Meyer, Efrat Broide, Maya Granot, Manar Matar, Seamus Hussey, Anat Yerushalmy‐Feler, Christoph Norden, Erasmo Miele, Marina Aloi   +11 more
wiley   +1 more source

Optimizing the Treatment of Atopic Dermatitis in Infants Using Ursodeoxycholic Acid

Zdorovʹe Rebenka, 2016
We have determined the advisability of including a suspension of ursodeoxycholic acid into the treatment of atopic dermatitis in infants. It is proved that taking a suspension of ursodeoxycholic acid in 25 infants with atopic dermatitis leads to a ...
O.H. Shadrin, H.A. Haiduchyk
doaj   +3 more sources

Pharmacotherapy for primary biliary cholangitis: an assessment of medication candidacy and rates of treatment

BMC Gastroenterology
Background Ursodeoxycholic acid is the preferred first-line therapy for primary biliary cholangitis. Alternative therapies, such as obeticholic acid, are recommended for patients who cannot tolerate ursodeoxycholic acid or who have an inadequate response
Nicholas MacDonald, Rebecca Loh, Jonathan M. Fenkel, David A. Sass, Dina Halegoua-DeMarzio   +4 more
doaj   +1 more source

The Neuroprotective Effect of Ursodeoxycholic-acid in Comparison with Carbamazepine in Pilocarpine Induced Status Epilepticus in Experimental Rats

مجله كليه طب الكندي
Background: An epileptic seizure was defined as a transient occurrence of signs and symptoms due to abnormal excessive neuronal activity in the brain. A seizure lasting 30 minutes or longer or a series of seizures in which the patient did not regain
Zainab Adel Omran, Ahmed Hamed Jwied
doaj   +1 more source

Enzymatic quantification of total serum bile acids as a monitoring strategy for women with intrahepatic cholestasis of pregnancy receiving ursodeoxycholic acid treatment: a cohort study

BJOG: an International Journal of Obstetrics and Gynaecology, 2019
To evaluate enzymatic total serum bile acid quantification as a monitoring strategy for women with intrahepatic cholestasis of pregnancy (ICP) treated with ursodeoxycholic acid (UDCA).
Luiza Borges Manna, Caroline Ovadia, A. Lövgren-Sandblom, J. Chambers, S. Begum, P. Seed, Ian A. L. Walker, L. Chappell, H. Marschall, C. Williamson   +9 more
semanticscholar   +1 more source

A case of autoimmune hepatitis in a patient with inflammatory bowel disease and significant lymphadenopathy in the porta hepatis

JPGN Reports, EarlyView.
Abstract The diagnosis of autoimmune hepatitis (AIH) is supported by the presence of elevated transaminases, hypergammaglobulinemia, liver biopsy consistent with AIH, and the presence of AIH autoantibodies. In this case presentation, we highlight the challenges associated with diagnosing AIH in a patient with inflammatory bowel disease (IBD) who ...
Benjamin J. Malamet, Shannon Joerger, Karen Caudill, Mai He, Juan Reyes Genere, Janis Stoll   +5 more
wiley   +1 more source

Thin-layer chromatographic separation of conjugates of ursodeoxycholic acid from those of litho-, chenodeoxy-, deoxy-, and cholic acids.

Journal of Lipid Research, 1981
Separation of the glycine and taurine conjugates of ursodeoxycholic acid from those of lithocholic acid, chenodeoxycholic acid, deoxycholic acid, and cholic acid by thin-layer chromatography is described.
A K Batta, S Shefer, G Salen
doaj   +1 more source

Maralixibat for the treatment of severe xanthomas in two children with Alagille syndrome: Case reports

JPGN Reports, EarlyView.
Abstract Alagille syndrome (ALGS) is a rare, autosomal dominant disorder which presents with a broad range of clinical manifestations, including cholestatic pruritus. A unique manifestation of ALGS is the presence of xanthomas in 24%–42% of patients, which can lead to liver transplantation.
Geetanjali Bora, Ruben E. Quiros‐Tejeira, Bernadette Vitola   +2 more
wiley   +1 more source

Clinical efficasy of L-arginine and ursodeoxycholic acid in the complex treatment of rosacea

Vestnik Dermatologii i Venerologii, 2017
Under clinical observation were 77 patients suffered from different clinical forms of acne rosacea that using L-arginin and Ursodeoxycholic acid had treated All patients have functional and organic disturbances of hepatobiliary system before treatment ...
M. K. Baltabaev, A. T. Shakirova, A. M. Baltabaev   +2 more
doaj   +1 more source

Ursodeoxycholic acid: A promising therapeutic target for inflammatory bowel diseases?

American Journal of Physiology - Gastrointestinal and Liver Physiology, 2019
The secondary bile acid, ursodeoxycholic acid (UDCA), has long been known to have medicinal properties. As the therapeutically active component of bear bile, it has been used for centuries in traditional Chinese Medicine to treat a range of conditions ...
S. Keely, C. Steer, Natalia K. Lajczak-McGinley   +2 more
semanticscholar   +1 more source