Results 201 to 210 of about 61,926,370 (366)

Molecular bases of circadian magnesium rhythms across eukaryotes

FEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Usability Evaluation of the Karafs Application: A Qualitative Study Using the Think-Aloud Method. [PDF]

Health Sci Rep
Bohlouly F, Kheirdoust A, Ghaddaripouri K, Sheibani R, Mazaheri Habibi MR.   +4 more
europepmc   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

Comprehensive usability evaluation of electronic prescription systems: integrating expert and user perspectives. [PDF]

BMC Med Inform Decis Mak
Arabian S, Hajesmaeel-Gohari S, Zarei AH, Alizadeh Savareh B, Bashiri A.   +4 more
europepmc   +1 more source

Measuring the Conformation and Persistence Length of Single-Stranded DNA Using a DNA Origami Structure [PDF]

, 2018
Efrat Roth, Alex Glick Azaria, Olga Girshevitz, Arkady Bitler, Yuval Garini   +4 more
openalex   +1 more source

The Factor Structure of the System Usability Scale

Interacción, 2009
James R. Lewis, Jeff Sauro
semanticscholar   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

FEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang, Grace Du, Charity Yongo‐Luwawa, Angelina Lu, Brett Kinrade, Kim Munro, Karl E. Klose, William D. Lubell, Peter Davies, Shuaiqi Guo   +9 more
wiley   +1 more source

Engineering therapeutic bispecific antibodies using CrossMab technology

, 2018
Christian Klein, Wolfgang Schaefer, Jörg T. Regula, Charles Dumontet, Ulrich Brinkmann, Marina Bacac, Pablo Umaña   +6 more
openalex   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

A structured framework to improve usability in EHR implementation: a user-centered case study in Brazilian mental healthcare. [PDF]

Front Digit Health
Gaspary FP, Amaral DB, Fagundes CV, Lopes LFD, Gaspary JFP.   +4 more
europepmc   +1 more source