Results 141 to 150 of about 9,578 (166)

Abstract 3665: Insilco evaluation of multiple ubiquitin-specific protease 1 (USP1) inhibitors and selectivity profiling over other USPs using Alphafold

Cancer Research
Abstract DNA damage triggers cell signaling cascades that mediate repair. This signaling is frequently dysregulated in cancers. The proteins that mediate this signaling are potential targets for therapeutic intervention. Ubiquitin-specific protease 1 (USP1) is one such target, with small-molecule inhibitors already in clinical trials ...
Prashant Kashinath Bhavar, Uday Kumar Surampudi, Appaji Baburao Mandhare, Rupesh Chikhale   +3 more
openaire   +1 more source

Corrigendum to “Subquinocin, a small molecule inhibitor of CYLD and USP-family deubiquitinating enzymes, promotes NF-κB signaling” [Biochem. Biophys. Res. Commun. 524 (1) (2020) 1–7]

Biochemical and Biophysical Research Communications, 2021
Satoshi Yamanaka, Yusuke Sato, Daisuke Oikawa, Eiji Goto, Shuya Fukai, Fuminori Tokunaga, Hirotaka Takahashi, Tatsuya Sawasaki   +7 more
openaire   +1 more source

USP INHIBITOR, PREPARATION METHOD THEREFOR, AND APPLICATION

2023
LIU XIAOHUI, WANG YUXUN, ZHANG WEI
openaire   +1 more source

Review for "The deubiquitinating enzyme <scp>USP</scp> 8 promotes tyrosine kinase inhibitors resistance in chronic myeloid leukemia by stabilizing <scp>EIF</scp> 2 <scp>S</scp> 1 protein"

  +5 more sources

A novel USP apparatus 4 based release testing method for dispersed systems

International Journal of Pharmaceutics, 2010
Diane Burgess
exaly  

Systematic Error Associated with Apparatus 2 of the USP Dissolution Test III: Limitations of Calibrators and the USP Suitability Test

Journal of Pharmaceutical Sciences, 1983
Terry W Moore
exaly  

Evaluation of USP apparatus 3 for dissolution testing of immediate-release products

AAPS PharmSci, 2015
Lawrence X Yu, Ajaz S Hussain
exaly  

20E-regulated USP expression and phosphorylation in Drosophila melanogaster

Insect Biochemistry and Molecular Biology, 2003
Qisheng Song
exaly  

PKC-Mediated USP Phosphorylation at Ser35 Modulates 20-Hydroxyecdysone Signaling in Drosophila

Journal of Proteome Research, 2012
Qisheng Song, Sheng Li, Sheng Wang
exaly  

Typical variability in drug dissolution testing: study with USP and FDA calibrator tablets and a marketed drug (glibenclamide) product

European Journal of Pharmaceutical Sciences, 1999
Saeed A Qureshi, I J Mcgilveray
exaly