Results 51 to 60 of about 9,578 (166)

Unravelling the role of ubiquitin-specific proteases in breast carcinoma: insights into tumour progression and immune microenvironment modulation

open access: yesWorld Journal of Surgical Oncology
Breast cancer is a prevalent malignancy worldwide, and its treatment has increasingly shifted towards precision medicine, with immunotherapy emerging as a key therapeutic strategy.
Huiyuan Yang   +7 more
doaj   +1 more source

Effects of Asymmetric Auditory Deprivation in Sequential Cochlear Implant

open access: yesOtolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective To evaluate the influence of auditory deprivation on sequential cochlear implants in postlingual patients, comparing the ear with shorter deprivation (ESAD), longer deprivation (ELAD), and the bilateral condition (BIL). Study design Retrospective study. Setting A tertiary referral center.
Eduardo S. Farinazzo   +4 more
wiley   +1 more source

Main‐chain polyfullerenes: Taking fullerene to the next dimension

open access: yesPolymer International, EarlyView.
This short review appraises main‐chain polyfullerenes. Their slow development over 30 years has suddenly boomed with a rapid growth due to exciting developments in solar energy. Abstract This mini‐review gives an overview of the development, chemistry, properties and applications of main‐chain polyfullerenes.
Marco Antônio GB Gomes   +4 more
wiley   +1 more source

Resistência da planta daninha capim-marmelada (Brachiaria plantaginea) aos herbicidas inibidores da enzima ACCase na cultura da soja Alexandergrass (Brachiaria plantaginea) resistance to ACCase inhibitor herbicides

open access: yesPlanta Daninha, 2000
Populações de capim-marmelada (Brachiaria plantaginea) infestantes da cultura da soja (Glycine max (L.) Merrill) no município de Mangueirinha, PR, controlada, ano após ano, com herbicidas inibidores da ACCase, apresentaram falhas de controle quando esses
Dionisio L. P. Gazziero   +4 more
doaj   +1 more source

Structural Insights Into the Function of Leishmania major Adenylosuccinate Lyase

open access: yesProteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT One of several intriguing aspects of kinetoplastid biochemistry is the complete dependence on host purines and purine recycling due to the lack of a de novo purine biosynthesis pathway. Adenylosuccinate lyase (ASL, EC 4.3.2.2) is a key enzyme in the purine synthesis pathway responsible for the conversion of adenylosuccinate into adenosine ...
Ivan R. e Silva   +10 more
wiley   +1 more source

Ashwagandha: Is It Safe? Part 1: A Regulatory Review

open access: yesPhytotherapy Research, EarlyView.
ABSTRACT Over the last decade, ashwagandha (Withania somnifera (L.) Dunal, AS) has been brought under increasing scrutiny by EU regulators regarding its safety for the use in food supplements, culminating in a recent recommendation for an Article 8 procedure according to Regulation (EC) No. 1925/2006 in the European Union (EU).
T. Brendler   +5 more
wiley   +1 more source

Ubiquitin-specific peptidases in lymphoma: a path to novel therapeutics

open access: yesFrontiers in Pharmacology
BackgroundUbiquitin-specific peptidases (USPs), also known as deubiquitinating enzymes (DUBs), play a crucial role in maintaining cellular homeostasis by selectively removing ubiquitin molecules from targeted proteins.
Maryam Samareh Salavatipour   +12 more
doaj   +1 more source

Seasonal Variation in Carbon Dynamics in the Lower Tocantins River: Influence of Discharge and Environmental Drivers

open access: yesRiver Research and Applications, EarlyView.
ABSTRACT Tropical rivers play a key role in regional carbon budgets, yet greenhouse gas (GHG) dynamics in regulated systems remain poorly understood. This study investigates the seasonal variability of carbon dioxide (CO2) and methane (CH4) concentrations, isotopic composition (δ13C), and river‐atmosphere fluxes in the lower Tocantins River, a ...
Maria Gabriella da S. Araújo   +5 more
wiley   +1 more source

Physiological and transcriptomic analyses reveal the molecular networks of responses induced by exogenous trehalose in plant.

open access: yesPLoS ONE, 2019
It is well known that exogenous trehalose can improve resistances of plants to some abiotic and biotic stresses. Nonetheless, information respecting the molecular responses of tobacco leaves to Tre treatment is limited.
Yongchun Shi   +6 more
doaj   +1 more source

Presence of Nationally Banned Carbamates and Organophosphate Pesticides in Wild Carnivores, Southeastern Brazil

open access: yesEnvironmental Toxicology, EarlyView.
ABSTRACT As top predators, terrestrial carnivores face great risk of pesticide exposure and serve as sentinels of environmental contamination. Additionally, terrestrial carnivores are frequently threatened by intentional or secondary poisoning with highly toxic compounds, such as carbamates and organophosphates.
Marina Pellegrino da Silva   +10 more
wiley   +1 more source

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